Scores & Fixtures 2015-2016 Eredivisie
| Wk | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sat | 2015-08-08 | 19:45 | Roda JC | 3–1 | Heracles Almelo | 13,472 | Parkstad Limburg Stadion | Ed Janssen | Match Report | |
| 1 | Sat | 2015-08-08 | 20:45 | Feyenoord | 3–2 | Utrecht | 47,500 | Stadion Feijenoord | Kevin Blom | Match Report | |
| 1 | Sun | 2015-08-09 | 12:30 | AZ Alkmaar | 0–3 | Ajax | 16,673 | AFAS Stadion | Björn Kuipers | Match Report | |
| 1 | Sun | 2015-08-09 | 16:45 | Willem II | 1–1 | Vitesse | 14,000 | Koning Willem II Stadion | Jochem Kamphuis | Match Report | |
| 1 | Tue | 2015-08-11 | 18:30 | ADO Den Haag | 2–2 | PSV Eindhoven | 13,125 | Cars Jeans Stadion | Richard Liesveld | Match Report | |
| 1 | Tue | 2015-08-11 | 20:45 | Heerenveen | 3–1 | De Graafschap | 20,000 | Abe Lenstra Stadion | Edwin van de Graaf | Match Report | |
| 1 | Wed | 2015-08-12 | 18:30 | Groningen | 1–1 | Twente | 22,241 | Hitachi Capital Mobility Stadion | Ed Janssen | Match Report | |
| 1 | Wed | 2015-08-12 | 19:45 | Zwolle | 2–2 | Cambuur | 11,650 | MAC³PARK Stadion | Dennis Higler | Match Report | |
| 1 | Wed | 2015-08-12 | 20:45 | NEC Nijmegen | 1–0 | Excelsior | 10,240 | Goffertstadion | Jeroen Manschot | Match Report | |
| 2 | Fri | 2015-08-14 | 20:00 | Vitesse | 3–0 | Roda JC | 13,212 | GelreDome | Eric Braamhaar | Match Report | |
| 2 | Sat | 2015-08-15 | 18:30 | De Graafschap | 0–3 | Zwolle | 8,100 | Stadion De Vijverberg | Allard Lindhout | Match Report | |
| 2 | Sat | 2015-08-15 | 19:45 | Ajax | 3–0 | Willem II | 48,494 | Johan Cruyff ArenA | Bas Nijhuis | Match Report | |
| 2 | Sat | 2015-08-15 | 19:45 | Twente | 1–4 | ADO Den Haag | 24,900 | De Grolsch Veste | Serdar Gözübüyük | Match Report | |
| 2 | Sat | 2015-08-15 | 20:45 | Excelsior | 2–2 | AZ Alkmaar | 3,394 | Van Donge & De Roo Stadion | Martin van den Kerkhof | Match Report | |
| 2 | Sun | 2015-08-16 | 12:30 | PSV Eindhoven | 2–0 | Groningen | 32,000 | Philips Stadion | Danny Makkelie | Match Report | |
| 2 | Sun | 2015-08-16 | 14:30 | Cambuur | 0–2 | Feyenoord | 10,000 | Cambuurstadion | Pol van Boekel | Match Report | |
| 2 | Sun | 2015-08-16 | 14:30 | Utrecht | 1–1 | Heerenveen | 15,800 | Stadion Galgenwaard | Björn Kuipers | Match Report | |
| 2 | Sun | 2015-08-16 | 16:45 | Heracles Almelo | 3–0 | NEC Nijmegen | 12,084 | Polman Stadion | Jochem Kamphuis | Match Report | |
| 3 | Fri | 2015-08-21 | 20:00 | Groningen | 2–0 | Excelsior | 19,277 | Hitachi Capital Mobility Stadion | Edwin van de Graaf | Match Report | |
| 3 | Sat | 2015-08-22 | 18:30 | Roda JC | 1–0 | De Graafschap | 13,130 | Parkstad Limburg Stadion | Bas Nijhuis | Match Report | |
| 3 | Sat | 2015-08-22 | 19:45 | Heerenveen | 1–1 | PSV Eindhoven | 24,645 | Abe Lenstra Stadion | Eric Braamhaar | Match Report | |
| 3 | Sat | 2015-08-22 | 20:45 | Cambuur | 1–6 | Heracles Almelo | 9,630 | Cambuurstadion | Richard Liesveld | Match Report | |
| 3 | Sun | 2015-08-23 | 12:30 | Zwolle | 2–1 | Twente | 12,123 | MAC³PARK Stadion | Kevin Blom | Match Report | |
| 3 | Sun | 2015-08-23 | 14:30 | ADO Den Haag | 1–1 | Utrecht | 12,293 | Cars Jeans Stadion | Pol van Boekel | Match Report | |
| 3 | Sun | 2015-08-23 | 14:30 | AZ Alkmaar | 0–0 | Willem II | 14,144 | AFAS Stadion | Ed Janssen | Match Report | |
| 3 | Sun | 2015-08-23 | 14:30 | NEC Nijmegen | 0–2 | Ajax | 12,321 | Goffertstadion | Dennis Higler | Match Report | |
| 3 | Sun | 2015-08-23 | 16:45 | Feyenoord | 2–0 | Vitesse | 47,500 | Stadion Feijenoord | Serdar Gözübüyük | Match Report | |
| 4 | Fri | 2015-08-28 | 20:00 | Willem II | 0–1 | NEC Nijmegen | 10,500 | Koning Willem II Stadion | Martin van den Kerkhof | Match Report | |
| 4 | Sat | 2015-08-29 | 18:30 | Utrecht | 2–0 | Groningen | 14,507 | Stadion Galgenwaard | Richard Liesveld | Match Report | |
| 4 | Sat | 2015-08-29 | 19:45 | Heerenveen | 1–1 | Zwolle | 24,200 | Abe Lenstra Stadion | Pol van Boekel | Match Report | |
| 4 | Sat | 2015-08-29 | 19:45 | Excelsior | 3–0 | De Graafschap | 3,300 | Van Donge & De Roo Stadion | Jochem Kamphuis | Match Report | |
| 4 | Sat | 2015-08-29 | 20:45 | Heracles Almelo | 2–0 | Twente | 12,100 | Polman Stadion | Dennis Higler | Match Report | |
| 4 | Sun | 2015-08-30 | 12:30 | Ajax | 4–0 | ADO Den Haag | 43,578 | Johan Cruyff ArenA | Danny Makkelie | Match Report | |
| 4 | Sun | 2015-08-30 | 14:30 | AZ Alkmaar | 0–1 | Roda JC | 14,226 | AFAS Stadion | Jeroen Manschot | Match Report | |
| 4 | Sun | 2015-08-30 | 14:30 | Vitesse | 4–1 | Cambuur | GelreDome | Allard Lindhout | Match Report | ||
| 4 | Sun | 2015-08-30 | 16:45 | PSV Eindhoven | 3–1 | Feyenoord | 35,000 | Philips Stadion | Björn Kuipers | Match Report | |
| 5 | Sat | 2015-09-12 | 18:30 | De Graafschap | 1–3 | AZ Alkmaar | 8,564 | Stadion De Vijverberg | Dennis Higler | Match Report | |
| 5 | Sat | 2015-09-12 | 18:30 | Roda JC | 0–0 | NEC Nijmegen | 13,967 | Parkstad Limburg Stadion | Björn Kuipers | Match Report | |
| 5 | Sat | 2015-09-12 | 19:45 | Twente | 2–2 | Ajax | 29,000 | De Grolsch Veste | Pol van Boekel | Match Report | |
| 5 | Sat | 2015-09-12 | 20:45 | Zwolle | 3–0 | Excelsior | 11,800 | MAC³PARK Stadion | Danny Makkelie | Match Report | |
| 5 | Sat | 2015-09-12 | 20:45 | Cambuur | 0–6 | PSV Eindhoven | 9,821 | Cambuurstadion | Kevin Blom | Match Report | |
| 5 | Sun | 2015-09-13 | 12:30 | Groningen | 3–1 | Heerenveen | 19,000 | Hitachi Capital Mobility Stadion | Serdar Gözübüyük | Match Report | |
| 5 | Sun | 2015-09-13 | 14:30 | Feyenoord | 1–0 | Willem II | 47,500 | Stadion Feijenoord | Richard Liesveld | Match Report | |
| 5 | Sun | 2015-09-13 | 14:30 | ADO Den Haag | 0–1 | Heracles Almelo | 10,071 | Cars Jeans Stadion | Jeroen Manschot | Match Report | |
| 5 | Sun | 2015-09-13 | 16:45 | Utrecht | 2–1 | Vitesse | 16,056 | Stadion Galgenwaard | Bas Nijhuis | Match Report | |
| 6 | Fri | 2015-09-18 | 20:00 | NEC Nijmegen | 2–0 | Heerenveen | 10,118 | Goffertstadion | Allard Lindhout | Match Report | |
| 6 | Sat | 2015-09-19 | 18:30 | Cambuur | 0–0 | Twente | 9,714 | Cambuurstadion | Jochem Kamphuis | Match Report | |
| 6 | Sat | 2015-09-19 | 19:45 | Zwolle | 2–1 | ADO Den Haag | 12,150 | MAC³PARK Stadion | Ed Janssen | Match Report | |
| 6 | Sat | 2015-09-19 | 19:45 | Heracles Almelo | 2–1 | PSV Eindhoven | 12,034 | Polman Stadion | Serdar Gözübüyük | Match Report | |
| 6 | Sat | 2015-09-19 | 20:45 | Willem II | 3–1 | Utrecht | 11,600 | Koning Willem II Stadion | Siemen Mulder | Match Report | |
| 6 | Sun | 2015-09-20 | 12:30 | Roda JC | 1–1 | Feyenoord | 17,142 | Parkstad Limburg Stadion | Pol van Boekel | Match Report | |
| 6 | Sun | 2015-09-20 | 14:30 | Excelsior | 0–2 | Ajax | 3,750 | Van Donge & De Roo Stadion | Kevin Blom | Match Report | |
| 6 | Sun | 2015-09-20 | 16:45 | Groningen | 2–0 | AZ Alkmaar | 19,389 | Hitachi Capital Mobility Stadion | Bas Nijhuis | Match Report | |
| 6 | Sun | 2015-09-20 | 16:45 | Vitesse | 3–0 | De Graafschap | 15,139 | GelreDome | Martin van den Kerkhof | Match Report | |
| 7 | Sat | 2015-09-26 | 18:30 | Utrecht | 3–3 | Cambuur | 16,073 | Stadion Galgenwaard | Edwin van de Graaf | Match Report | |
| 7 | Sat | 2015-09-26 | 18:30 | Heerenveen | 0–0 | Vitesse | 23,984 | Abe Lenstra Stadion | Dennis Higler | Match Report | |
| 7 | Sat | 2015-09-26 | 19:45 | Ajax | 2–0 | Groningen | 45,676 | Johan Cruyff ArenA | Richard Liesveld | Match Report | |
| 7 | Sat | 2015-09-26 | 20:45 | PSV Eindhoven | 2–1 | NEC Nijmegen | 32,500 | Philips Stadion | Danny Makkelie | Match Report | |
| 7 | Sat | 2015-09-26 | 20:45 | AZ Alkmaar | 3–1 | Heracles Almelo | 13,121 | AFAS Stadion | Pol van Boekel | Match Report | |
| 7 | Sun | 2015-09-27 | 12:30 | De Graafschap | 2–2 | Willem II | 9,183 | Stadion De Vijverberg | Ed Janssen | Match Report | |
| 7 | Sun | 2015-09-27 | 14:30 | ADO Den Haag | 3–3 | Excelsior | 10,667 | Cars Jeans Stadion | Siemen Mulder | Match Report | |
| 7 | Sun | 2015-09-27 | 14:30 | Feyenoord | 2–0 | Zwolle | 47,500 | Stadion Feijenoord | Björn Kuipers | Match Report | |
| 7 | Sun | 2015-09-27 | 16:45 | Twente | 2–1 | Roda JC | 24,700 | De Grolsch Veste | Serdar Gözübüyük | Match Report | |
| 8 | Fri | 2015-10-02 | 20:00 | Heracles Almelo | 2–0 | Heerenveen | 10,780 | Polman Stadion | Martin van den Kerkhof | Match Report | |
| 8 | Sat | 2015-10-03 | 18:30 | NEC Nijmegen | 4–1 | ADO Den Haag | 11,534 | Goffertstadion | Kevin Blom | Match Report | |
| 8 | Sat | 2015-10-03 | 19:45 | Roda JC | 1–1 | Cambuur | 14,489 | Parkstad Limburg Stadion | Jeroen Manschot | Match Report | |
| 8 | Sat | 2015-10-03 | 19:45 | Willem II | 0–1 | Zwolle | 11,500 | Koning Willem II Stadion | Richard Liesveld | Match Report | |
| 8 | Sat | 2015-10-03 | 20:45 | Excelsior | 1–0 | Utrecht | 3,430 | Van Donge & De Roo Stadion | Allard Lindhout | Match Report | |
| 8 | Sun | 2015-10-04 | 12:30 | De Graafschap | 1–2 | Feyenoord | 12,145 | Stadion De Vijverberg | Danny Makkelie | Match Report | |
| 8 | Sun | 2015-10-04 | 14:30 | Ajax | 1–2 | PSV Eindhoven | 51,154 | Johan Cruyff ArenA | Bas Nijhuis | Match Report | |
| 8 | Sun | 2015-10-04 | 14:30 | Vitesse | 5–0 | Groningen | 16,185 | GelreDome | Björn Kuipers | Match Report | |
| 8 | Sun | 2015-10-04 | 16:45 | AZ Alkmaar | 3–1 | Twente | 13,711 | AFAS Stadion | Ed Janssen | Match Report | |
| 9 | Sat | 2015-10-17 | 18:30 | Groningen | 2–1 | Willem II | 21,787 | Hitachi Capital Mobility Stadion | Dennis Higler | Match Report | |
| 9 | Sat | 2015-10-17 | 18:30 | Cambuur | 1–1 | AZ Alkmaar | 9,666 | Cambuurstadion | Siemen Mulder | Match Report | |
| 9 | Sat | 2015-10-17 | 19:45 | Heracles Almelo | 0–2 | Ajax | 12,080 | Polman Stadion | Kevin Blom | Match Report | |
| 9 | Sat | 2015-10-17 | 20:45 | Utrecht | 1–1 | Roda JC | 15,779 | Stadion Galgenwaard | Bas Nijhuis | Match Report | |
| 9 | Sat | 2015-10-17 | 20:45 | PSV Eindhoven | 1–1 | Excelsior | 32,800 | Philips Stadion | Jochem Kamphuis | Match Report | |
| 9 | Sun | 2015-10-18 | 12:30 | Twente | 1–0 | NEC Nijmegen | 24,500 | De Grolsch Veste | Jeroen Manschot | Match Report | |
| 9 | Sun | 2015-10-18 | 14:30 | Heerenveen | 2–5 | Feyenoord | 25,350 | Abe Lenstra Stadion | Serdar Gözübüyük | Match Report | |
| 9 | Sun | 2015-10-18 | 14:30 | ADO Den Haag | 1–1 | De Graafschap | 10,512 | Cars Jeans Stadion | Björn Kuipers | Match Report | |
| 9 | Sun | 2015-10-18 | 16:45 | Zwolle | 1–5 | Vitesse | 12,250 | MAC³PARK Stadion | Pol van Boekel | Match Report | |
| 10 | Fri | 2015-10-23 | 20:00 | Zwolle | 1–2 | Utrecht | 12,300 | MAC³PARK Stadion | Eric Braamhaar | Match Report | |
| 10 | Sat | 2015-10-24 | 18:30 | Willem II | 2–2 | Heerenveen | 13,500 | Koning Willem II Stadion | Jeroen Manschot | Match Report | |
| 10 | Sat | 2015-10-24 | 19:45 | De Graafschap | 0–1 | Heracles Almelo | 10,362 | Stadion De Vijverberg | Jochem Kamphuis | Match Report | |
| 10 | Sat | 2015-10-24 | 19:45 | Twente | 1–3 | PSV Eindhoven | 25,500 | De Grolsch Veste | Kevin Blom | Match Report | |
| 10 | Sat | 2015-10-24 | 20:45 | Roda JC | 1–2 | Excelsior | 13,907 | Parkstad Limburg Stadion | Martin van den Kerkhof | Match Report | |
| 10 | Sun | 2015-10-25 | 12:30 | Cambuur | 1–1 | ADO Den Haag | 9,519 | Cambuurstadion | Dennis Higler | Match Report | |
| 10 | Sun | 2015-10-25 | 14:30 | Vitesse | 1–3 | Ajax | 21,163 | GelreDome | Richard Liesveld | Match Report | |
| 10 | Sun | 2015-10-25 | 14:30 | NEC Nijmegen | 1–1 | Groningen | 11,630 | Goffertstadion | Ed Janssen | Match Report | |
| 10 | Sun | 2015-10-25 | 16:45 | Feyenoord | 3–1 | AZ Alkmaar | 47,500 | Stadion Feijenoord | Björn Kuipers | Match Report | |
| 11 | Fri | 2015-10-30 | 20:00 | Heracles Almelo | 2–1 | Willem II | 11,123 | Polman Stadion | Ed Janssen | Match Report | |
| 11 | Sat | 2015-10-31 | 18:30 | Groningen | 2–0 | Zwolle | 21,565 | Hitachi Capital Mobility Stadion | Jeroen Manschot | Match Report | |
| 11 | Sat | 2015-10-31 | 19:45 | Excelsior | 0–3 | Vitesse | 3,600 | Van Donge & De Roo Stadion | Jochem Kamphuis | Match Report | |
| 11 | Sat | 2015-10-31 | 19:45 | Ajax | 6–0 | Roda JC | 50,681 | Johan Cruyff ArenA | Björn Kuipers | Match Report | |
| 11 | Sat | 2015-10-31 | 20:45 | De Graafschap | 3–6 | PSV Eindhoven | 11,163 | Stadion De Vijverberg | Bas Nijhuis | Match Report | |
| 11 | Sun | 2015-11-01 | 12:30 | ADO Den Haag | 1–0 | Feyenoord | 14,261 | Cars Jeans Stadion | Kevin Blom | Match Report | |
| 11 | Sun | 2015-11-01 | 14:30 | Utrecht | 4–2 | Twente | 17,034 | Stadion Galgenwaard | Dennis Higler | Match Report | |
| 11 | Sun | 2015-11-01 | 14:30 | Heerenveen | 2–0 | Cambuur | 26,100 | Abe Lenstra Stadion | Richard Liesveld | Match Report | |
| 11 | Sun | 2015-11-01 | 16:45 | AZ Alkmaar | 2–4 | NEC Nijmegen | 15,555 | AFAS Stadion | Martin van den Kerkhof | Match Report | |
| 12 | Fri | 2015-11-06 | 20:00 | Roda JC | 1–1 | ADO Den Haag | 14,182 | Parkstad Limburg Stadion | Eric Braamhaar | Match Report | |
| 12 | Sat | 2015-11-07 | 18:30 | Twente | 1–4 | Heerenveen | 25,600 | De Grolsch Veste | Jochem Kamphuis | Match Report | |
| 12 | Sat | 2015-11-07 | 19:45 | Willem II | 2–3 | Excelsior | 11,200 | Koning Willem II Stadion | Pol van Boekel | Match Report | |
| 12 | Sat | 2015-11-07 | 19:45 | NEC Nijmegen | 2–0 | De Graafschap | 11,673 | Goffertstadion | Richard Liesveld | Match Report | |
| 12 | Sat | 2015-11-07 | 20:45 | Zwolle | 1–1 | Heracles Almelo | 12,420 | MAC³PARK Stadion | Dennis Higler | Match Report | |
| 12 | Sun | 2015-11-08 | 12:30 | PSV Eindhoven | 3–1 | Utrecht | 34,100 | Philips Stadion | Björn Kuipers | Match Report | |
| 12 | Sun | 2015-11-08 | 14:30 | Cambuur | 2–2 | Groningen | 9,813 | Cambuurstadion | Serdar Gözübüyük | Match Report | |
| 12 | Sun | 2015-11-08 | 14:30 | Feyenoord | 1–1 | Ajax | 47,500 | Stadion Feijenoord | Bas Nijhuis | Match Report | |
| 12 | Sun | 2015-11-08 | 16:45 | Vitesse | 0–2 | AZ Alkmaar | 15,327 | GelreDome | Ed Janssen | Match Report | |
| 13 | Sat | 2015-11-21 | 18:30 | AZ Alkmaar | 3–1 | Heerenveen | 15,521 | AFAS Stadion | Allard Lindhout | Match Report | |
| 13 | Sat | 2015-11-21 | 18:30 | Roda JC | 0–5 | Zwolle | 14,378 | Parkstad Limburg Stadion | Danny Makkelie | Match Report | |
| 13 | Sat | 2015-11-21 | 19:45 | Ajax | 5–1 | Cambuur | 47,932 | Johan Cruyff ArenA | Ed Janssen | Match Report | |
| 13 | Sat | 2015-11-21 | 20:45 | Willem II | 2–2 | PSV Eindhoven | 14,112 | Koning Willem II Stadion | Serdar Gözübüyük | Match Report | |
| 13 | Sat | 2015-11-21 | 20:45 | De Graafschap | 1–2 | Groningen | 10,083 | Stadion De Vijverberg | Edwin van de Graaf | Match Report | |
| 13 | Sun | 2015-11-22 | 12:30 | Heracles Almelo | 0–0 | Excelsior | 11,721 | Polman Stadion | Siemen Mulder | Match Report | |
| 13 | Sun | 2015-11-22 | 14:30 | NEC Nijmegen | 1–0 | Utrecht | 11,509 | Goffertstadion | Pol van Boekel | Match Report | |
| 13 | Sun | 2015-11-22 | 14:30 | Feyenoord | 5–0 | Twente | 47,500 | Stadion Feijenoord | Richard Liesveld | Match Report | |
| 13 | Sun | 2015-11-22 | 16:45 | ADO Den Haag | 2–2 | Vitesse | 12,113 | Cars Jeans Stadion | Bas Nijhuis | Match Report | |
| 14 | Fri | 2015-11-27 | 20:00 | Cambuur | 2–3 | De Graafschap | 10,000 | Cambuurstadion | Danny Makkelie | Match Report | |
| 14 | Sat | 2015-11-28 | 18:30 | Heerenveen | 3–0 | Roda JC | 22,850 | Abe Lenstra Stadion | Pol van Boekel | Match Report | |
| 14 | Sat | 2015-11-28 | 19:45 | Excelsior | 2–4 | Feyenoord | 3,750 | Van Donge & De Roo Stadion | Eric Braamhaar | Match Report | |
| 14 | Sat | 2015-11-28 | 20:45 | Twente | 1–3 | Willem II | 24,100 | De Grolsch Veste | Jeroen Manschot | Match Report | |
| 14 | Sun | 2015-11-29 | 12:30 | Vitesse | 1–0 | NEC Nijmegen | 19,212 | GelreDome | Björn Kuipers | Match Report | |
| 14 | Sun | 2015-11-29 | 14:30 | Groningen | 2–1 | ADO Den Haag | 19,480 | Hitachi Capital Mobility Stadion | Dennis Higler | Match Report | |
| 14 | Sun | 2015-11-29 | 14:30 | Zwolle | 0–2 | Ajax | 12,500 | MAC³PARK Stadion | Kevin Blom | Match Report | |
| 14 | Sun | 2015-11-29 | 14:30 | Utrecht | 4–2 | Heracles Almelo | 18,144 | Stadion Galgenwaard | Jochem Kamphuis | Match Report | |
| 14 | Sun | 2015-11-29 | 16:45 | PSV Eindhoven | 3–0 | AZ Alkmaar | 33,000 | Philips Stadion | Richard Liesveld | Match Report | |
| 15 | Fri | 2015-12-04 | 20:00 | AZ Alkmaar | 0–1 | ADO Den Haag | 13,743 | AFAS Stadion | Björn Kuipers | Match Report | |
| 15 | Sat | 2015-12-05 | 18:30 | Excelsior | 1–1 | Twente | 3,400 | Van Donge & De Roo Stadion | Martin van den Kerkhof | Match Report | |
| 15 | Sat | 2015-12-05 | 19:45 | De Graafschap | 0–1 | Utrecht | 10,175 | Stadion De Vijverberg | Siemen Mulder | Match Report | |
| 15 | Sat | 2015-12-05 | 19:45 | Vitesse | 0–1 | PSV Eindhoven | 16,879 | GelreDome | Kevin Blom | Match Report | |
| 15 | Sat | 2015-12-05 | 20:45 | Ajax | 5–2 | Heerenveen | 47,544 | Johan Cruyff ArenA | Danny Makkelie | Match Report | |
| 15 | Sun | 2015-12-06 | 12:30 | Willem II | 3–0 | Cambuur | 12,050 | Koning Willem II Stadion | Dennis Higler | Match Report | |
| 15 | Sun | 2015-12-06 | 14:30 | Feyenoord | 3–0 | Heracles Almelo | 47,500 | Stadion Feijenoord | Bas Nijhuis | Match Report | |
| 15 | Sun | 2015-12-06 | 14:30 | NEC Nijmegen | 2–2 | Zwolle | 10,503 | Goffertstadion | Serdar Gözübüyük | Match Report | |
| 15 | Sun | 2015-12-06 | 16:45 | Roda JC | 0–0 | Groningen | 13,171 | Parkstad Limburg Stadion | Ed Janssen | Match Report | |
| 16 | Fri | 2015-12-11 | 20:00 | Heerenveen | 2–1 | Excelsior | 22,150 | Abe Lenstra Stadion | Edwin van de Graaf | Match Report | |
| 16 | Sat | 2015-12-12 | 18:30 | ADO Den Haag | 1–1 | Willem II | 11,703 | Cars Jeans Stadion | Allard Lindhout | Match Report | |
| 16 | Sat | 2015-12-12 | 19:45 | Cambuur | 3–1 | NEC Nijmegen | 9,718 | Cambuurstadion | Jeroen Manschot | Match Report | |
| 16 | Sat | 2015-12-12 | 19:45 | PSV Eindhoven | 1–1 | Roda JC | 33,700 | Philips Stadion | Eric Braamhaar | Match Report | |
| 16 | Sat | 2015-12-12 | 20:45 | Twente | 2–1 | De Graafschap | 25,100 | De Grolsch Veste | Ed Janssen | Match Report | |
| 16 | Sun | 2015-12-13 | 12:30 | Utrecht | 1–0 | Ajax | 14,100 | Stadion Galgenwaard | Serdar Gözübüyük | Match Report | |
| 16 | Sun | 2015-12-13 | 14:30 | Zwolle | 2–1 | AZ Alkmaar | 12,120 | MAC³PARK Stadion | Jochem Kamphuis | Match Report | |
| 16 | Sun | 2015-12-13 | 14:30 | Groningen | 1–1 | Feyenoord | 22,091 | Hitachi Capital Mobility Stadion | Pol van Boekel | Match Report | |
| 16 | Sun | 2015-12-13 | 16:45 | Heracles Almelo | 1–1 | Vitesse | 10,821 | Polman Stadion | Richard Liesveld | Match Report | |
| 17 | Fri | 2015-12-18 | 20:00 | Vitesse | 5–1 | Twente | 15,987 | GelreDome | Serdar Gözübüyük | Match Report | |
| 17 | Sat | 2015-12-19 | 18:30 | AZ Alkmaar | 2–2 | Utrecht | 15,756 | AFAS Stadion | Bas Nijhuis | Match Report | |
| 17 | Sat | 2015-12-19 | 19:45 | PSV Eindhoven | 3–2 | Zwolle | 34,000 | Philips Stadion | Dennis Higler | Match Report | |
| 17 | Sat | 2015-12-19 | 20:45 | Heracles Almelo | 2–1 | Groningen | 10,622 | Polman Stadion | Danny Makkelie | Match Report | |
| 17 | Sun | 2015-12-20 | 12:30 | Excelsior | 1–4 | Cambuur | 3,750 | Van Donge & De Roo Stadion | Pol van Boekel | Match Report | |
| 17 | Sun | 2015-12-20 | 14:30 | NEC Nijmegen | 3–1 | Feyenoord | 12,500 | Goffertstadion | Eric Braamhaar | Match Report | |
| 17 | Sun | 2015-12-20 | 14:30 | Willem II | 3–2 | Roda JC | 13,000 | Koning Willem II Stadion | Siemen Mulder | Match Report | |
| 17 | Sun | 2015-12-20 | 14:30 | Heerenveen | 0–4 | ADO Den Haag | 23,122 | Abe Lenstra Stadion | Jeroen Manschot | Match Report | |
| 17 | Sun | 2015-12-20 | 16:45 | Ajax | 2–1 | De Graafschap | 50,882 | Johan Cruyff ArenA | Richard Liesveld | Match Report | |
| 18 | Fri | 2016-01-15 | 20:00 | Twente | 4–0 | Heracles Almelo | 28,900 | De Grolsch Veste | Kevin Blom | Match Report | |
| 18 | Sat | 2016-01-16 | 18:30 | Cambuur | 0–2 | Vitesse | 9,508 | Cambuurstadion | Eric Braamhaar | Match Report | |
| 18 | Sat | 2016-01-16 | 19:45 | Zwolle | 5–2 | Heerenveen | 12,320 | MAC³PARK Stadion | Martin van den Kerkhof | Match Report | |
| 18 | Sat | 2016-01-16 | 19:45 | Roda JC | 0–1 | AZ Alkmaar | 13,516 | Parkstad Limburg Stadion | Allard Lindhout | Match Report | |
| 18 | Sat | 2016-01-16 | 20:45 | De Graafschap | 2–0 | Excelsior | 10,253 | Stadion De Vijverberg | Dennis Higler | Match Report | |
| 18 | Sun | 2016-01-17 | 12:30 | ADO Den Haag | 0–1 | Ajax | 14,561 | Cars Jeans Stadion | Pol van Boekel | Match Report | |
| 18 | Sun | 2016-01-17 | 14:30 | Feyenoord | 0–2 | PSV Eindhoven | 47,500 | Stadion Feijenoord | Danny Makkelie | Match Report | |
| 18 | Sun | 2016-01-17 | 14:30 | Groningen | 1–4 | Utrecht | 20,545 | Hitachi Capital Mobility Stadion | Björn Kuipers | Match Report | |
| 18 | Sun | 2016-01-17 | 16:45 | NEC Nijmegen | 1–0 | Willem II | 11,682 | Goffertstadion | Jochem Kamphuis | Match Report | |
| 19 | Fri | 2016-01-22 | 20:00 | Groningen | 0–0 | NEC Nijmegen | 20,163 | Hitachi Capital Mobility Stadion | Bas Nijhuis | Match Report | |
| 19 | Sat | 2016-01-23 | 18:30 | Heracles Almelo | 2–1 | De Graafschap | 10,451 | Polman Stadion | Siemen Mulder | Match Report | |
| 19 | Sat | 2016-01-23 | 19:45 | Excelsior | 0–1 | Roda JC | 3,500 | Van Donge & De Roo Stadion | Ed Janssen | Match Report | |
| 19 | Sat | 2016-01-23 | 19:45 | Ajax | 1–0 | Vitesse | 48,533 | Johan Cruyff ArenA | Björn Kuipers | Match Report | |
| 19 | Sat | 2016-01-23 | 20:45 | Heerenveen | 3–1 | Willem II | 22,150 | Abe Lenstra Stadion | Danny Makkelie | Match Report | |
| 19 | Sun | 2016-01-24 | 12:30 | AZ Alkmaar | 4–2 | Feyenoord | 15,127 | AFAS Stadion | Richard Liesveld | Match Report | |
| 19 | Sun | 2016-01-24 | 14:30 | Utrecht | 1–0 | Zwolle | 21,715 | Stadion Galgenwaard | Kevin Blom | Match Report | |
| 19 | Sun | 2016-01-24 | 14:30 | PSV Eindhoven | 4–2 | Twente | 33,000 | Philips Stadion | Pol van Boekel | Match Report | |
| 19 | Sun | 2016-01-24 | 16:45 | ADO Den Haag | 2–1 | Cambuur | 10,342 | Cars Jeans Stadion | Serdar Gözübüyük | Match Report | |
| 20 | Tue | 2016-01-26 | 18:30 | Willem II | 1–1 | Groningen | 12,000 | Koning Willem II Stadion | Allard Lindhout | Match Report | |
| 20 | Tue | 2016-01-26 | 20:45 | Ajax | 0–0 | Heracles Almelo | 44,517 | Johan Cruyff ArenA | Dennis Higler | Match Report | |
| 20 | Wed | 2016-01-27 | 18:30 | AZ Alkmaar | 3–1 | Cambuur | 14,017 | AFAS Stadion | Jeroen Manschot | Match Report | |
| 20 | Wed | 2016-01-27 | 18:30 | NEC Nijmegen | 2–0 | Twente | 10,958 | Goffertstadion | Edwin van de Graaf | Match Report | |
| 20 | Wed | 2016-01-27 | 19:45 | De Graafschap | 3–1 | ADO Den Haag | 9,763 | Stadion De Vijverberg | Martin van den Kerkhof | Match Report | |
| 20 | Wed | 2016-01-27 | 20:45 | Vitesse | 1–1 | Zwolle | 14,876 | GelreDome | Ed Janssen | Match Report | |
| 20 | Wed | 2016-01-27 | 20:45 | Excelsior | 1–3 | PSV Eindhoven | 3,700 | Van Donge & De Roo Stadion | Bas Nijhuis | Match Report | |
| 20 | Thu | 2016-01-28 | 18:30 | Roda JC | 1–0 | Utrecht | 13,605 | Parkstad Limburg Stadion | Danny Makkelie | Match Report | |
| 20 | Thu | 2016-01-28 | 20:45 | Feyenoord | 1–2 | Heerenveen | 47,500 | Stadion Feijenoord | Pol van Boekel | Match Report | |
| 21 | Fri | 2016-01-29 | 20:00 | Willem II | 0–0 | Heracles Almelo | 13,100 | Koning Willem II Stadion | Ed Janssen | Match Report | |
| 21 | Sat | 2016-01-30 | 18:30 | Vitesse | 0–0 | Excelsior | 20,112 | GelreDome | Jeroen Manschot | Match Report | |
| 21 | Sat | 2016-01-30 | 19:45 | PSV Eindhoven | 4–2 | De Graafschap | 32,500 | Philips Stadion | Björn Kuipers | Match Report | |
| 21 | Sat | 2016-01-30 | 19:45 | Zwolle | 1–3 | Groningen | 12,225 | MAC³PARK Stadion | Dennis Higler | Match Report | |
| 21 | Sat | 2016-01-30 | 20:45 | NEC Nijmegen | 0–3 | AZ Alkmaar | 12,130 | Goffertstadion | Martin van den Kerkhof | Match Report | |
| 21 | Sun | 2016-01-31 | 12:30 | Roda JC | 2–2 | Ajax | 17,654 | Parkstad Limburg Stadion | Serdar Gözübüyük | Match Report | |
| 21 | Sun | 2016-01-31 | 14:30 | Cambuur | 0–1 | Heerenveen | 10,000 | Cambuurstadion | Richard Liesveld | Match Report | |
| 21 | Sun | 2016-01-31 | 14:30 | Feyenoord | 0–2 | ADO Den Haag | 47,500 | Stadion Feijenoord | Danny Makkelie | Match Report | |
| 21 | Sun | 2016-01-31 | 16:45 | Twente | 3–1 | Utrecht | 24,400 | De Grolsch Veste | Siemen Mulder | Match Report | |
| 22 | Fri | 2016-02-05 | 20:00 | Excelsior | 0–0 | Willem II | 3,500 | Van Donge & De Roo Stadion | Edwin van de Graaf | Match Report | |
| 22 | Sat | 2016-02-06 | 18:30 | ADO Den Haag | 2–2 | Roda JC | 11,349 | Cars Jeans Stadion | Siemen Mulder | Match Report | |
| 22 | Sat | 2016-02-06 | 19:45 | AZ Alkmaar | 1–0 | Vitesse | 15,006 | AFAS Stadion | Bas Nijhuis | Match Report | |
| 22 | Sat | 2016-02-06 | 19:45 | Heerenveen | 1–3 | Twente | 23,125 | Abe Lenstra Stadion | Dennis Higler | Match Report | |
| 22 | Sat | 2016-02-06 | 20:45 | Heracles Almelo | 2–0 | Zwolle | 10,543 | Polman Stadion | Pol van Boekel | Match Report | |
| 22 | Sun | 2016-02-07 | 12:30 | Ajax | 2–1 | Feyenoord | 51,875 | Johan Cruyff ArenA | Kevin Blom | Match Report | |
| 22 | Sun | 2016-02-07 | 14:30 | De Graafschap | 1–1 | NEC Nijmegen | 10,123 | Stadion De Vijverberg | Allard Lindhout | Match Report | |
| 22 | Sun | 2016-02-07 | 14:30 | Groningen | 2–0 | Cambuur | 20,743 | Hitachi Capital Mobility Stadion | Danny Makkelie | Match Report | |
| 22 | Sun | 2016-02-07 | 16:45 | Utrecht | 0–2 | PSV Eindhoven | 19,224 | Stadion Galgenwaard | Serdar Gözübüyük | Match Report | |
| 23 | Fri | 2016-02-12 | 20:00 | Cambuur | 0–2 | Utrecht | 9,710 | Cambuurstadion | Bas Nijhuis | Match Report | |
| 23 | Sat | 2016-02-13 | 18:30 | Heracles Almelo | 3–6 | AZ Alkmaar | 11,096 | Polman Stadion | Björn Kuipers | Match Report | |
| 23 | Sat | 2016-02-13 | 19:45 | Willem II | 0–0 | De Graafschap | 12,000 | Koning Willem II Stadion | Pol van Boekel | Match Report | |
| 23 | Sat | 2016-02-13 | 19:45 | Roda JC | 0–1 | Twente | 15,012 | Parkstad Limburg Stadion | Jeroen Manschot | Match Report | |
| 23 | Sat | 2016-02-13 | 20:45 | Vitesse | 3–0 | Heerenveen | 15,234 | GelreDome | Siemen Mulder | Match Report | |
| 23 | Sun | 2016-02-14 | 12:30 | Groningen | 1–2 | Ajax | 22,107 | Hitachi Capital Mobility Stadion | Richard Liesveld | Match Report | |
| 23 | Sun | 2016-02-14 | 14:30 | Zwolle | 3–1 | Feyenoord | 12,500 | MAC³PARK Stadion | Serdar Gözübüyük | Match Report | |
| 23 | Sun | 2016-02-14 | 14:30 | Excelsior | 2–4 | ADO Den Haag | 3,519 | Van Donge & De Roo Stadion | Ed Janssen | Match Report | |
| 23 | Sun | 2016-02-14 | 16:45 | NEC Nijmegen | 0–3 | PSV Eindhoven | 12,353 | Goffertstadion | Kevin Blom | Match Report | |
| 24 | Fri | 2016-02-19 | 20:00 | ADO Den Haag | 0–2 | Zwolle | 11,784 | Cars Jeans Stadion | Jeroen Manschot | Match Report | |
| 24 | Sat | 2016-02-20 | 18:30 | AZ Alkmaar | 4–1 | Groningen | 16,325 | AFAS Stadion | Kevin Blom | Match Report | |
| 24 | Sat | 2016-02-20 | 19:45 | PSV Eindhoven | 2–0 | Heracles Almelo | 33,400 | Philips Stadion | Danny Makkelie | Match Report | |
| 24 | Sat | 2016-02-20 | 19:45 | Heerenveen | 1–1 | NEC Nijmegen | 22,412 | Abe Lenstra Stadion | Ed Janssen | Match Report | |
| 24 | Sat | 2016-02-20 | 20:45 | Twente | 3–0 | Cambuur | 25,200 | De Grolsch Veste | Allard Lindhout | Match Report | |
| 24 | Sun | 2016-02-21 | 12:30 | De Graafschap | 2–2 | Vitesse | 12,218 | Stadion De Vijverberg | Serdar Gözübüyük | Match Report | |
| 24 | Sun | 2016-02-21 | 14:30 | Utrecht | 2–1 | Willem II | 17,398 | Stadion Galgenwaard | Martin van den Kerkhof | Match Report | |
| 24 | Sun | 2016-02-21 | 14:30 | Ajax | 3–0 | Excelsior | 48,800 | Johan Cruyff ArenA | Dennis Higler | Match Report | |
| 24 | Sun | 2016-02-21 | 16:45 | Feyenoord | 1–1 | Roda JC | 47,500 | Stadion Feijenoord | Richard Liesveld | Match Report | |
| 25 | Fri | 2016-02-26 | 20:00 | Excelsior | 2–0 | NEC Nijmegen | 3,523 | Van Donge & De Roo Stadion | Björn Kuipers | Match Report | |
| 25 | Sat | 2016-02-27 | 18:30 | Twente | 2–0 | Groningen | 25,200 | De Grolsch Veste | Martin van den Kerkhof | Match Report | |
| 25 | Sat | 2016-02-27 | 19:45 | PSV Eindhoven | 2–0 | ADO Den Haag | 33,500 | Philips Stadion | Dennis Higler | Match Report | |
| 25 | Sat | 2016-02-27 | 19:45 | Cambuur | 1–0 | Zwolle | 9,775 | Cambuurstadion | Siemen Mulder | Match Report | |
| 25 | Sat | 2016-02-27 | 20:45 | Vitesse | 0–1 | Willem II | 15,987 | GelreDome | Richard Liesveld | Match Report | |
| 25 | Sun | 2016-02-28 | 12:30 | Heracles Almelo | 0–5 | Roda JC | 10,055 | Polman Stadion | Edwin van de Graaf | Match Report | |
| 25 | Sun | 2016-02-28 | 14:30 | De Graafschap | 0–1 | Heerenveen | 12,314 | Stadion De Vijverberg | Kevin Blom | Match Report | |
| 25 | Sun | 2016-02-28 | 14:30 | Utrecht | 1–2 | Feyenoord | 18,512 | Stadion Galgenwaard | Pol van Boekel | Match Report | |
| 25 | Sun | 2016-02-28 | 16:45 | Ajax | 4–1 | AZ Alkmaar | 51,313 | Johan Cruyff ArenA | Serdar Gözübüyük | Match Report | |
| 26 | Fri | 2016-03-04 | 20:00 | ADO Den Haag | 2–1 | Twente | 13,128 | Cars Jeans Stadion | Kevin Blom | Match Report | |
| 26 | Sat | 2016-03-05 | 18:30 | Zwolle | 2–1 | De Graafschap | 12,250 | MAC³PARK Stadion | Edwin van de Graaf | Match Report | |
| 26 | Sat | 2016-03-05 | 19:45 | Groningen | 0–3 | PSV Eindhoven | 21,983 | Hitachi Capital Mobility Stadion | Pol van Boekel | Match Report | |
| 26 | Sat | 2016-03-05 | 20:45 | Heerenveen | 0–4 | Utrecht | 21,300 | Abe Lenstra Stadion | Serdar Gözübüyük | Match Report | |
| 26 | Sun | 2016-03-06 | 12:30 | NEC Nijmegen | 1–0 | Heracles Almelo | 12,438 | Goffertstadion | Jeroen Manschot | Match Report | |
| 26 | Sun | 2016-03-06 | 14:30 | AZ Alkmaar | 2–0 | Excelsior | 15,050 | AFAS Stadion | Bas Nijhuis | Match Report | |
| 26 | Sun | 2016-03-06 | 14:30 | Willem II | 0–4 | Ajax | 14,500 | Koning Willem II Stadion | Danny Makkelie | Match Report | |
| 26 | Sun | 2016-03-06 | 14:30 | Roda JC | 1–2 | Vitesse | 15,184 | Parkstad Limburg Stadion | Allard Lindhout | Match Report | |
| 26 | Sun | 2016-03-06 | 16:45 | Feyenoord | 3–1 | Cambuur | 47,500 | Stadion Feijenoord | Dennis Higler | Match Report | |
| 27 | Fri | 2016-03-11 | 20:00 | De Graafschap | 3–0 | Roda JC | 12,032 | Stadion De Vijverberg | Ed Janssen | Match Report | |
| 27 | Sat | 2016-03-12 | 18:30 | Twente | 2–1 | Zwolle | 27,200 | De Grolsch Veste | Danny Makkelie | Match Report | |
| 27 | Sat | 2016-03-12 | 19:45 | Willem II | 0–2 | AZ Alkmaar | 12,000 | Koning Willem II Stadion | Edwin van de Graaf | Match Report | |
| 27 | Sat | 2016-03-12 | 19:45 | PSV Eindhoven | 1–1 | Heerenveen | 34,100 | Philips Stadion | Richard Liesveld | Match Report | |
| 27 | Sat | 2016-03-12 | 20:45 | Excelsior | 2–1 | Groningen | 3,605 | Van Donge & De Roo Stadion | Serdar Gözübüyük | Match Report | |
| 27 | Sun | 2016-03-13 | 12:30 | Utrecht | 2–2 | ADO Den Haag | 14,164 | Stadion Galgenwaard | Siemen Mulder | Match Report | |
| 27 | Sun | 2016-03-13 | 14:30 | Heracles Almelo | 3–1 | Cambuur | 10,627 | Polman Stadion | Jochem Kamphuis | Match Report | |
| 27 | Sun | 2016-03-13 | 14:30 | Vitesse | 0–2 | Feyenoord | 20,000 | GelreDome | Björn Kuipers | Match Report | |
| 27 | Sun | 2016-03-13 | 16:45 | Ajax | 2–2 | NEC Nijmegen | 50,168 | Johan Cruyff ArenA | Pol van Boekel | Match Report | |
| 28 | Fri | 2016-03-18 | 20:00 | Utrecht | 2–1 | Excelsior | 16,081 | Stadion Galgenwaard | Edwin van de Graaf | Match Report | |
| 28 | Sat | 2016-03-19 | 18:30 | Heerenveen | 0–1 | Heracles Almelo | 24,500 | Abe Lenstra Stadion | Allard Lindhout | Match Report | |
| 28 | Sat | 2016-03-19 | 19:45 | Zwolle | 4–1 | Willem II | 12,185 | MAC³PARK Stadion | Jochem Kamphuis | Match Report | |
| 28 | Sat | 2016-03-19 | 19:45 | Feyenoord | 3–1 | De Graafschap | 47,000 | Stadion Feijenoord | Bas Nijhuis | Match Report | |
| 28 | Sat | 2016-03-19 | 20:45 | Cambuur | 0–1 | Roda JC | 9,762 | Cambuurstadion | Danny Makkelie | Match Report | |
| 28 | Sun | 2016-03-20 | 12:30 | Twente | 2–2 | AZ Alkmaar | 25,000 | De Grolsch Veste | Pol van Boekel | Match Report | |
| 28 | Sun | 2016-03-20 | 14:30 | ADO Den Haag | 1–0 | NEC Nijmegen | 10,784 | Cars Jeans Stadion | Martin van den Kerkhof | Match Report | |
| 28 | Sun | 2016-03-20 | 14:30 | Groningen | 0–3 | Vitesse | 21,331 | Hitachi Capital Mobility Stadion | Ed Janssen | Match Report | |
| 28 | Sun | 2016-03-20 | 16:45 | PSV Eindhoven | 0–2 | Ajax | 35,000 | Philips Stadion | Björn Kuipers | Match Report | |
| 29 | Sat | 2016-04-02 | 18:30 | De Graafschap | 2–2 | Cambuur | 12,600 | Stadion De Vijverberg | Pol van Boekel | Match Report | |
| 29 | Sat | 2016-04-02 | 18:30 | Heracles Almelo | 1–1 | Utrecht | 12,011 | Polman Stadion | Martin van den Kerkhof | Match Report | |
| 29 | Sat | 2016-04-02 | 19:45 | AZ Alkmaar | 2–4 | PSV Eindhoven | 17,052 | AFAS Stadion | Serdar Gözübüyük | Match Report | |
| 29 | Sat | 2016-04-02 | 20:45 | Willem II | 2–3 | Twente | 13,110 | Koning Willem II Stadion | Dennis Higler | Match Report | |
| 29 | Sat | 2016-04-02 | 20:45 | Feyenoord | 3–0 | Excelsior | 46,500 | Stadion Feijenoord | Richard Liesveld | Match Report | |
| 29 | Sun | 2016-04-03 | 12:30 | NEC Nijmegen | 2–1 | Vitesse | 12,500 | Goffertstadion | Danny Makkelie | Match Report | |
| 29 | Sun | 2016-04-03 | 14:30 | ADO Den Haag | 0–1 | Groningen | 11,891 | Cars Jeans Stadion | Bas Nijhuis | Match Report | |
| 29 | Sun | 2016-04-03 | 14:30 | Roda JC | 1–2 | Heerenveen | 15,259 | Parkstad Limburg Stadion | Björn Kuipers | Match Report | |
| 29 | Sun | 2016-04-03 | 16:45 | Ajax | 3–0 | Zwolle | 51,862 | Johan Cruyff ArenA | Kevin Blom | Match Report | |
| 30 | Fri | 2016-04-08 | 20:00 | Zwolle | 3–1 | Roda JC | 12,500 | MAC³PARK Stadion | Siemen Mulder | Match Report | |
| 30 | Sat | 2016-04-09 | 18:30 | Excelsior | 1–3 | Heracles Almelo | 3,750 | Van Donge & De Roo Stadion | Björn Kuipers | Match Report | |
| 30 | Sat | 2016-04-09 | 19:45 | Vitesse | 2–2 | ADO Den Haag | 16,298 | GelreDome | Jochem Kamphuis | Match Report | |
| 30 | Sat | 2016-04-09 | 19:45 | Cambuur | 0–1 | Ajax | 10,000 | Cambuurstadion | Pieter Vink | Match Report | |
| 30 | Sat | 2016-04-09 | 20:45 | PSV Eindhoven | 2–0 | Willem II | 34,500 | Philips Stadion | Bas Nijhuis | Match Report | |
| 30 | Sun | 2016-04-10 | 12:30 | Heerenveen | 4–2 | AZ Alkmaar | 23,100 | Abe Lenstra Stadion | Kevin Blom | Match Report | |
| 30 | Sun | 2016-04-10 | 14:30 | Groningen | 3–1 | De Graafschap | 22,425 | Hitachi Capital Mobility Stadion | Jeroen Manschot | Match Report | |
| 30 | Sun | 2016-04-10 | 14:30 | Utrecht | 3–1 | NEC Nijmegen | 18,729 | Stadion Galgenwaard | Ed Janssen | Match Report | |
| 30 | Sun | 2016-04-10 | 16:45 | Twente | 0–1 | Feyenoord | 27,600 | De Grolsch Veste | Serdar Gözübüyük | Match Report | |
| 31 | Fri | 2016-04-15 | 20:00 | De Graafschap | 1–1 | Twente | 12,600 | Stadion De Vijverberg | Allard Lindhout | Match Report | |
| 31 | Sat | 2016-04-16 | 18:30 | Vitesse | 1–1 | Heracles Almelo | 21,231 | GelreDome | Bas Nijhuis | Match Report | |
| 31 | Sat | 2016-04-16 | 19:45 | AZ Alkmaar | 5–1 | Zwolle | 16,341 | AFAS Stadion | Jeroen Manschot | Match Report | |
| 31 | Sat | 2016-04-16 | 19:45 | Feyenoord | 1–1 | Groningen | 47,500 | Stadion Feijenoord | Dennis Higler | Match Report | |
| 31 | Sat | 2016-04-16 | 20:45 | Roda JC | 0–3 | PSV Eindhoven | 17,159 | Parkstad Limburg Stadion | Kevin Blom | Match Report | |
| 31 | Sun | 2016-04-17 | 12:30 | Ajax | 2–2 | Utrecht | 51,768 | Johan Cruyff ArenA | Danny Makkelie | Match Report | |
| 31 | Sun | 2016-04-17 | 14:30 | NEC Nijmegen | 2–1 | Cambuur | 12,334 | Goffertstadion | Siemen Mulder | Match Report | |
| 31 | Sun | 2016-04-17 | 14:30 | Willem II | 0–2 | ADO Den Haag | 13,100 | Koning Willem II Stadion | Ed Janssen | Match Report | |
| 31 | Sun | 2016-04-17 | 16:45 | Excelsior | 1–1 | Heerenveen | 3,750 | Van Donge & De Roo Stadion | Edwin van de Graaf | Match Report | |
| 32 | Tue | 2016-04-19 | 18:30 | Groningen | 1–0 | Roda JC | 20,798 | Hitachi Capital Mobility Stadion | Martin van den Kerkhof | Match Report | |
| 32 | Tue | 2016-04-19 | 20:45 | PSV Eindhoven | 2–0 | Vitesse | 34,000 | Philips Stadion | Pieter Vink | Match Report | |
| 32 | Wed | 2016-04-20 | 18:30 | Zwolle | 2–0 | NEC Nijmegen | 12,352 | MAC³PARK Stadion | Edwin van de Graaf | Match Report | |
| 32 | Wed | 2016-04-20 | 18:30 | Utrecht | 0–2 | De Graafschap | 19,431 | Stadion Galgenwaard | Jochem Kamphuis | Match Report | |
| 32 | Wed | 2016-04-20 | 19:45 | Heracles Almelo | 2–2 | Feyenoord | 12,024 | Polman Stadion | Danny Makkelie | Match Report | |
| 32 | Wed | 2016-04-20 | 20:45 | Heerenveen | 0–2 | Ajax | 25,950 | Abe Lenstra Stadion | Serdar Gözübüyük | Match Report | |
| 32 | Wed | 2016-04-20 | 20:45 | Twente | 2–0 | Excelsior | 24,500 | De Grolsch Veste | Ed Janssen | Match Report | |
| 32 | Thu | 2016-04-21 | 18:30 | Cambuur | 1–1 | Willem II | 9,600 | Cambuurstadion | Kevin Blom | Match Report | |
| 32 | Thu | 2016-04-21 | 18:30 | ADO Den Haag | 1–2 | AZ Alkmaar | 13,128 | Cars Jeans Stadion | Siemen Mulder | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | Willem II | 0–1 | Feyenoord | 13,670 | Koning Willem II Stadion | Pieter Vink | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | NEC Nijmegen | 1–2 | Roda JC | 12,145 | Goffertstadion | Jochem Kamphuis | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | AZ Alkmaar | 4–1 | De Graafschap | 16,799 | AFAS Stadion | Dennis Higler | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | Excelsior | 2–2 | Zwolle | 3,750 | Van Donge & De Roo Stadion | Bas Nijhuis | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | Ajax | 4–0 | Twente | 51,727 | Johan Cruyff ArenA | Kevin Blom | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | PSV Eindhoven | 6–2 | Cambuur | 34,000 | Philips Stadion | Björn Kuipers | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | Heracles Almelo | 1–1 | ADO Den Haag | 11,681 | Polman Stadion | Jeroen Manschot | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | Vitesse | 1–3 | Utrecht | 18,121 | GelreDome | Serdar Gözübüyük | Match Report | |
| 33 | Sun | 2016-05-01 | 14:30 | Heerenveen | 1–2 | Groningen | 25,385 | Abe Lenstra Stadion | Danny Makkelie | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | Roda JC | 2–3 | Willem II | 16,805 | Parkstad Limburg Stadion | Danny Makkelie | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | Feyenoord | 1–0 | NEC Nijmegen | 46,000 | Stadion Feijenoord | Ed Janssen | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | De Graafschap | 1–1 | Ajax | 12,600 | Stadion De Vijverberg | Björn Kuipers | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | Groningen | 2–1 | Heracles Almelo | 22,206 | Hitachi Capital Mobility Stadion | Pieter Vink | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | Twente | 2–2 | Vitesse | 26,500 | De Grolsch Veste | Reinold Wiedemeijer | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | Zwolle | 1–3 | PSV Eindhoven | 12,500 | MAC³PARK Stadion | Pol van Boekel | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | ADO Den Haag | 1–1 | Heerenveen | 12,753 | Cars Jeans Stadion | Kevin Blom | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | Utrecht | 1–3 | AZ Alkmaar | 20,792 | Stadion Galgenwaard | Bas Nijhuis | Match Report | |
| 34 | Sun | 2016-05-08 | 14:30 | Cambuur | 0–2 | Excelsior | 8,650 | Cambuurstadion | Dennis Higler | Match Report |
| Round | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Semi-finals | Thu | 2016-05-12 | 18:30 | Groningen | 2–1 | Heracles Almelo | 20,477 | Hitachi Capital Mobility Stadion | Ed Janssen | Match Report | Leg 1 of 2 |
| Semi-finals | Thu | 2016-05-12 | 20:45 | Zwolle | 0–0 | Utrecht | 8,125 | MAC³PARK Stadion | Kevin Blom | Match Report | Leg 1 of 2 |
| Semi-finals | Sun | 2016-05-15 | 12:30 | Heracles Almelo | 5–1 | Groningen | 10,744 | Polman Stadion | Pol van Boekel | Match Report | Leg 2 of 2; Heracles Almelo won; Required Extra Time |
| Semi-finals | Sun | 2016-05-15 | 14:30 | Utrecht | 5–2 | Zwolle | 15,126 | Stadion Galgenwaard | Dennis Higler | Match Report | Leg 2 of 2; Utrecht won |
| Finals | Thu | 2016-05-19 | 20:45 | Heracles Almelo | 1–1 | Utrecht | 11,521 | Polman Stadion | Pieter Vink | Match Report | Leg 1 of 2 |
| Finals | Sun | 2016-05-22 | 14:30 | Utrecht | 0–2 | Heracles Almelo | 18,980 | Stadion Galgenwaard | Björn Kuipers | Match Report | Leg 2 of 2; Heracles Almelo won |
| Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Mon | 2016-05-02 | 20:00 | Almere City | 4–1 | Emmen | 2,200 | Yanmar Stadion | Martin van den Kerkhof | Match Report | Leg 1 of 2 |
| Mon | 2016-05-02 | 20:00 | MVV Maastricht | 2–1 | Volendam | 4,326 | De Geusselt | Allard Lindhout | Match Report | Leg 1 of 2 |
| Fri | 2016-05-06 | 18:30 | Emmen | 1–4 | Almere City | 2,580 | De Oude Meerdijk | Jeroen Manschot | Match Report | Leg 2 of 2; Almere City won |
| Fri | 2016-05-06 | 20:45 | Volendam | 1–2 | MVV Maastricht | 3,590 | Kras Stadion | Bas Nijhuis | Match Report | Leg 2 of 2; MVV Maastricht won |
| Fri | 2016-05-13 | 18:30 | MVV Maastricht | 0–1 | De Graafschap | 7,733 | De Geusselt | Danny Makkelie | Match Report | Leg 1 of 2 |
| Fri | 2016-05-13 | 19:45 | FC Eindhoven | 1–0 | NAC Breda | 4,711 | Jan Louwers Stadion | Siemen Mulder | Match Report | Leg 1 of 2 |
| Fri | 2016-05-13 | 19:45 | Go Ahead Eag | 1–0 | VVV-Venlo | 9,320 | De Adelaarshorst | Edwin van de Graaf | Match Report | Leg 1 of 2 |
| Fri | 2016-05-13 | 20:45 | Almere City | 0–1 | Willem II | 3,200 | Yanmar Stadion | Allard Lindhout | Match Report | Leg 1 of 2 |
| Mon | 2016-05-16 | 12:30 | De Graafschap | 2–1 | MVV Maastricht | Stadion De Vijverberg | Siemen Mulder | Match Report | Leg 2 of 2; De Graafschap won | |
| Mon | 2016-05-16 | 14:30 | VVV-Venlo | 2–2 | Go Ahead Eag | Seacon Stadion De Koel | Pieter Vink | Match Report | Leg 2 of 2; Go Ahead Eag won | |
| Mon | 2016-05-16 | 14:30 | NAC Breda | 2–0 | FC Eindhoven | Rat Verlegh Stadion | Jeroen Manschot | Match Report | Leg 2 of 2; NAC Breda won | |
| Mon | 2016-05-16 | 16:45 | Willem II | 5–2 | Almere City | Koning Willem II Stadion | Bas Nijhuis | Match Report | Leg 2 of 2; Willem II won | |
| Thu | 2016-05-19 | 18:30 | NAC Breda | 2–1 | Willem II | 17,500 | Rat Verlegh Stadion | Dennis Higler | Match Report | Leg 1 of 2 |
| Thu | 2016-05-19 | 19:45 | Go Ahead Eag | 4–1 | De Graafschap | 9,689 | De Adelaarshorst | Bas Nijhuis | Match Report | Leg 1 of 2 |
| Sun | 2016-05-22 | 12:30 | De Graafschap | 1–1 | Go Ahead Eag | 12,381 | Stadion De Vijverberg | Kevin Blom | Match Report | Leg 2 of 2; Go Ahead Eag won |
| Sun | 2016-05-22 | 16:45 | Willem II | 3–1 | NAC Breda | Koning Willem II Stadion | Danny Makkelie | Match Report | Leg 2 of 2; Willem II won |
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