Scores & Fixtures 2016 Copa Libertadores
| Round | Wk | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| First stage | Tue | 2016-02-02 | 19:30 | Huracán ar | 1–0 | ve Caracas | Estadio Tomás Adolfo Ducó | Patricio Polic | Match Report | Leg 1 of 2 | ||
| First stage | Wed | 2016-02-03 | 18:45 | U César Vallejo pe | 1–1 | br São Paulo | Estadio Mansiche | Roddy Zambrano | Match Report | Leg 1 of 2 | ||
| First stage | Tue | 2016-02-02 | 21:45 | River Plate uy | 2–0 | cl U de Chile | Parque Federico Omar Saroldi | Patricio Loustau | Match Report | Leg 1 of 2 | ||
| First stage | Thu | 2016-02-04 | 17:30 | Independiente ec | 1–0 | py Guaraní | Estadio General Rumiñahui del Valle de L... | Juan Soto | Match Report | Leg 1 of 2 | ||
| First stage | Wed | 2016-02-03 | 20:15 | Puebla mx | 2–2 | ar Racing Club | Estadio Cuauhtémoc | Daniel Fedorczuk | Match Report | Leg 1 of 2 | ||
| First stage | Thu | 2016-02-04 | 20:45 | Oriente Petrolero bo | 1–3 | co Santa Fe | Estadio Ramón Aguilera Costas | Pericles Bassols Pegado Cortez | Match Report | Leg 1 of 2 | ||
| First stage | Tue | 2016-02-09 | 19:30 | U de Chile cl | 0–0 | uy River Plate | Estadio Nacional Julio Martínez Prádanos | Carlos Vera | Match Report | Leg 2 of 2; River Plate won | ||
| First stage | Tue | 2016-02-09 | 20:15 | Caracas ve | 2–1 | ar Huracán | Estadio Olímpico | Enrique Cáceres | Match Report | Leg 2 of 2; Huracán won | ||
| First stage | Wed | 2016-02-10 | 21:45 | São Paulo br | 1–0 | pe U César Vallejo | Estádio do Pacaembú | Christian Ferreyra | Match Report | Leg 2 of 2; São Paulo won | ||
| First stage | Thu | 2016-02-11 | 19:30 | Guaraní py | 2–1 | ec Independiente | Estadio Defensores del Chaco | Mauro Vigliano | Match Report | Leg 2 of 2; Independiente won | ||
| First stage | Wed | 2016-02-10 | 21:45 | Racing Club ar | 1–0 | mx Puebla | Estadio Presidente Juan Domingo Perón | Ricardo Marques Ribeiro | Match Report | Leg 2 of 2; Racing Club won | ||
| First stage | Thu | 2016-02-11 | 20:00 | Santa Fe co | 3–0 | bo Oriente Petrolero | Estadio Nemesio Camacho El Campín | Víctor Carrillo | Match Report | Leg 2 of 2; Santa Fe won | ||
| Second stage | 1 | Tue | 2016-02-16 | 20:45 | River Plate uy | 2–2 | br Palmeiras | Parque Federico Omar Saroldi | Julio Bascuñán | Match Report | ||
| Second stage | 1 | Wed | 2016-02-17 | 18:45 | Melgar pe | 1–2 | br Atlético Mineiro | Estadio de la Universidad Nacional San A... | Wilson Lamouroux | Match Report | ||
| Second stage | 1 | Wed | 2016-02-17 | 19:30 | São Paulo br | 0–1 | bo The Strongest | Estádio do Pacaembú | Mario Díaz de Vivar | Match Report | ||
| Second stage | 1 | Wed | 2016-02-17 | 20:45 | Cobresal cl | 0–1 | br Corinthians | Estadio El Cobre | Andrés Cunha | Match Report | ||
| Second stage | 1 | Tue | 2016-02-16 | 21:00 | Santa Fe co | 0–0 | py Cerro Porteño | Estadio Nemesio Camacho El Campín | Roberto García | Match Report | ||
| Second stage | 1 | Tue | 2016-02-16 | 21:30 | Dep Táchira ve | 2–1 | py Olimpia | Estadio Polideportivo de Pueblo Nuevo | Heber Roberto Lopes | Match Report | ||
| Second stage | 1 | Wed | 2016-02-17 | 20:00 | Toluca mx | 2–0 | br Grêmio | Estadio Nemesio Díez | Gery Vargas | Match Report | ||
| Second stage | 1 | Thu | 2016-02-18 | 19:45 | Sporting Cristal pe | 1–1 | uy Peñarol | Estadio Alberto Gallardo | Wilton Sampaio | Match Report | ||
| Second stage | 1 | Thu | 2016-02-18 | 19:45 | Independiente ec | 1–1 | cl Colo-Colo | Estadio General Rumiñahui del Valle de L... | José Argote | Match Report | ||
| Second stage | 1 | Thu | 2016-02-18 | 21:00 | UNAM mx | 4–2 | ec CS Emelec | Estadio Olímpico de Universitario | Diego Haro | Match Report | ||
| Second stage | 1 | Tue | 2016-02-23 | 17:30 | LDU de Quito ec | 2–0 | ar San Lorenzo | Jonathan Fuentes | Match Report | |||
| Second stage | 1 | Wed | 2016-02-24 | 19:30 | Racing Club ar | 4–1 | bo Bolívar | Estadio Presidente Juan Domingo Perón | Ulises Mereles | Match Report | ||
| Second stage | 2 | Wed | 2016-02-24 | 19:30 | Colo-Colo cl | 1–0 | pe Melgar | Estadio Monumental David Arellano | Julio Quintana | Match Report | ||
| Second stage | 1 | Tue | 2016-02-23 | 21:45 | Huracán ar | 0–2 | co Nacional | Estadio Tomás Adolfo Ducó | Roberto Tobar | Match Report | ||
| Second stage | 1 | Thu | 2016-02-25 | 19:30 | Rosario Central ar | 1–1 | uy Nacional | Estadio Dr. Lisandro de la Torre | Wilmar Roldán | Match Report | ||
| Second stage | 2 | Thu | 2016-02-25 | 19:30 | Cerro Porteño py | 2–1 | cl Cobresal | Estadio Defensores del Chaco | Néstor Pitana | Match Report | ||
| Second stage | 1 | Wed | 2016-02-24 | 19:45 | AD Cali co | 0–0 | ar Boca Juniors | Estadio Deportivo Cali | Pericles Bassols Pegado Cortez | Match Report | ||
| Second stage | 2 | Wed | 2016-02-24 | 21:45 | Atlético Mineiro br | 1–0 | ec Independiente | Estádio Raimundo Sampaio | Fernando Rapallini | Match Report | ||
| Second stage | 2 | Thu | 2016-02-25 | 19:45 | CS Emelec ec | 2–0 | ve Dep Táchira | Estadio Banco del Pacífico | Raúl Orozco | Match Report | ||
| Second stage | 1 | Thu | 2016-02-25 | 20:15 | Trujillanos ve | 0–4 | ar River Plate | Estadio José Alberto Pérez | Juan Bravo | Match Report | ||
| Second stage | 3 | Tue | 2016-03-01 | 15:15 | Melgar pe | 0–1 | ec Independiente | Estadio Mariano Melgar | Óscar Rojas | Match Report | ||
| Second stage | 2 | Tue | 2016-03-01 | 19:30 | Olimpia py | 0–2 | mx UNAM | Estadio Manuel Ferreira | Germán Delfino | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 16:15 | The Strongest bo | 2–1 | ve Trujillanos | Estadio Hernando Siles | Gustavo Murillo | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 19:30 | Nacional uy | 0–0 | uy River Plate | Estadio Gran Parque Central | Víctor Carrillo | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 19:30 | San Lorenzo ar | 1–1 | mx Toluca | Estadio Pedro Bidegaín | Enrique Osses | Match Report | ||
| Second stage | 2 | Tue | 2016-03-01 | 19:45 | Nacional co | 3–0 | pe Sporting Cristal | Estadio Atanasio Girardot | Óscar Maldonado | Match Report | ||
| Second stage | 2 | Tue | 2016-03-01 | 21:45 | Peñarol uy | 0–1 | ar Huracán | Estadio Centenario | César Arturo Ramos | Match Report | ||
| Second stage | 2 | Thu | 2016-03-03 | 19:30 | Boca Juniors ar | 0–0 | ar Racing Club | Estadio Alberto José Armando | Sandro Ricci | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 21:45 | Corinthians br | 1–0 | co Santa Fe | Arena Corinthians | Mauro Vigliano | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 21:45 | Grêmio br | 4–0 | ec LDU de Quito | Arena do Grêmio | Jesús Valenzuela | Match Report | ||
| Second stage | 2 | Thu | 2016-03-03 | 20:45 | Bolívar bo | 5–0 | co AD Cali | Estadio Hernando Siles | Klever Rojas | Match Report | ||
| Second stage | 2 | Thu | 2016-03-03 | 21:45 | Palmeiras br | 2–0 | ar Rosario Central | Allianz Parque | Enrique Cáceres | Match Report | ||
| Second stage | 3 | Tue | 2016-03-08 | 17:30 | CS Emelec ec | 2–2 | py Olimpia | Estadio Reales Tamarindos | Wilton Sampaio | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 17:15 | Cobresal cl | 1–2 | co Santa Fe | Estadio El Cobre | Juan Bravo | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 19:30 | Cerro Porteño py | 3–2 | br Corinthians | Estadio Defensores del Chaco | Diego Haro | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 19:30 | Rosario Central ar | 4–1 | uy River Plate | Estadio Dr. Lisandro de la Torre | Ulises Mereles | Match Report | ||
| Second stage | 3 | Tue | 2016-03-08 | 19:45 | Sporting Cristal pe | 3–2 | ar Huracán | Estadio Alberto Gallardo | Mario Díaz de Vivar | Match Report | ||
| Second stage | 3 | Tue | 2016-03-08 | 19:45 | Nacional co | 2–0 | uy Peñarol | Estadio Atanasio Girardot | Heber Roberto Lopes | Match Report | ||
| Second stage | 2 | Thu | 2016-03-10 | 19:30 | River Plate ar | 1–1 | br São Paulo | Estadio Monumental Antonio Vespucio Libe... | Julio Bascuñán | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 20:15 | Dep Táchira ve | 2–0 | mx UNAM | Estadio Polideportivo de Pueblo Nuevo | Jorge Baliño | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 21:45 | Palmeiras br | 1–2 | uy Nacional | Allianz Parque | Enrique Osses | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 21:45 | Grêmio br | 1–1 | ar San Lorenzo | Arena do Grêmio | Daniel Fedorczuk | Match Report | ||
| Second stage | 3 | Thu | 2016-03-10 | 19:45 | LDU de Quito ec | 1–2 | mx Toluca | Estadio de Liga Deportiva Universitaria | Wilson Lamouroux | Match Report | ||
| Second stage | 3 | Thu | 2016-03-10 | 20:45 | Bolívar bo | 1–1 | ar Boca Juniors | Estadio Hernando Siles | Andrés Cunha | Match Report | ||
| Second stage | 3 | Thu | 2016-03-10 | 21:45 | Colo-Colo cl | 0–0 | br Atlético Mineiro | Estadio Monumental David Arellano | Gery Vargas | Match Report | ||
| Second stage | 4 | Tue | 2016-03-15 | 17:30 | Independiente ec | 2–0 | pe Melgar | Estadio General Rumiñahui del Valle de L... | Raúl Orozco | Match Report | ||
| Second stage | 4 | Tue | 2016-03-15 | 17:30 | Santa Fe co | 3–0 | cl Cobresal | Estadio Nemesio Camacho El Campín | Óscar Maldonado | Match Report | ||
| Second stage | 3 | Wed | 2016-03-16 | 18:00 | Trujillanos ve | 1–1 | br São Paulo | Estadio José Alberto Pérez | Wilson Lamouroux | Match Report | ||
| Second stage | 3 | Wed | 2016-03-16 | 18:30 | The Strongest bo | 1–1 | ar River Plate | Estadio Hernando Siles | Julio Quintana | Match Report | ||
| Second stage | 4 | Tue | 2016-03-15 | 21:45 | San Lorenzo ar | 1–1 | br Grêmio | Estadio Pedro Bidegaín | Andrés Cunha | Match Report | ||
| Second stage | 4 | Tue | 2016-03-15 | 21:45 | Peñarol uy | 0–4 | co Nacional | Estadio Centenario | Julio Bascuñán | Match Report | ||
| Second stage | 4 | Thu | 2016-03-17 | 19:30 | River Plate uy | 1–3 | ar Rosario Central | Estadio Centenario | José Argote | Match Report | ||
| Second stage | 4 | Thu | 2016-03-17 | 19:30 | Olimpia py | 4–2 | ec CS Emelec | Estadio Defensores del Chaco | Darío Herrera | Match Report | ||
| Second stage | 4 | Wed | 2016-03-16 | 21:45 | Corinthians br | 2–0 | py Cerro Porteño | Arena Corinthians | Patricio Loustau | Match Report | ||
| Second stage | 4 | Wed | 2016-03-16 | 21:45 | Atlético Mineiro br | 3–0 | cl Colo-Colo | Estádio Raimundo Sampaio | Juan Soto | Match Report | ||
| Second stage | 3 | Thu | 2016-03-17 | 19:45 | AD Cali co | 2–2 | ar Racing Club | Estadio Deportivo Cali | Diego Haro | Match Report | ||
| Second stage | 4 | Thu | 2016-03-17 | 21:00 | UNAM mx | 4–1 | ve Dep Táchira | Estadio Olímpico Universitario de Colima | Ricardo Marques Ribeiro | Match Report | ||
| Second stage | 4 | Thu | 2016-03-17 | 21:45 | Nacional uy | 1–0 | br Palmeiras | Estadio Gran Parque Central | Luis Cordero | Match Report | ||
| Second stage | 5 | Tue | 2016-04-05 | 18:00 | Dep Táchira ve | 1–0 | ec CS Emelec | Estadio Polideportivo de Pueblo Nuevo | Christian Ferreyra | Match Report | ||
| Second stage | 4 | Tue | 2016-04-05 | 19:30 | Huracán ar | 4–2 | pe Sporting Cristal | Estadio Tomás Adolfo Ducó | Raphael Claus | Match Report | ||
| Second stage | 4 | Wed | 2016-04-06 | 19:30 | River Plate ar | 6–0 | bo The Strongest | Estadio Monumental Antonio Vespucio Libe... | Wilson Lamouroux | Match Report | ||
| Second stage | 4 | Tue | 2016-04-05 | 19:45 | Toluca mx | 2–1 | ec LDU de Quito | Estadio Nemesio Díez | José Argote | Match Report | ||
| Second stage | 4 | Tue | 2016-04-05 | 21:45 | São Paulo br | 6–0 | ve Trujillanos | Estádio do Morumbi | Ulises Mereles | Match Report | ||
| Second stage | 4 | Thu | 2016-04-07 | 19:30 | Boca Juniors ar | 3–1 | bo Bolívar | Estadio Alberto José Armando | Víctor Carrillo | Match Report | ||
| Second stage | 5 | Thu | 2016-04-07 | 19:30 | River Plate uy | 2–2 | uy Nacional | Estadio Centenario | Enrique Cáceres | Match Report | ||
| Second stage | 5 | Wed | 2016-04-06 | 19:45 | Santa Fe co | 1–1 | br Corinthians | Estadio Nemesio Camacho El Campín | Néstor Pitana | Match Report | ||
| Second stage | 5 | Wed | 2016-04-06 | 19:45 | Independiente ec | 3–2 | br Atlético Mineiro | Estadio General Rumiñahui del Valle de L... | Darío Herrera | Match Report | ||
| Second stage | 5 | Wed | 2016-04-06 | 21:45 | Rosario Central ar | 3–3 | br Palmeiras | Estadio Dr. Lisandro de la Torre | Juan Bravo | Match Report | ||
| Second stage | 5 | Wed | 2016-04-06 | 22:00 | UNAM mx | 4–1 | py Olimpia | Estadio Olímpico de Universitario | Julio Bascuñán | Match Report | ||
| Second stage | 5 | Thu | 2016-04-07 | 19:45 | Melgar pe | 1–2 | cl Colo-Colo | Estadio de la Universidad Nacional San A... | Luis Sánchez | Match Report | ||
| Second stage | 4 | Thu | 2016-04-07 | 21:45 | Racing Club ar | 4–2 | co AD Cali | Estadio Presidente Juan Domingo Perón | Heber Roberto Lopes | Match Report | ||
| Second stage | 5 | Tue | 2016-04-12 | 18:00 | Trujillanos ve | 2–1 | bo The Strongest | Estadio José Alberto Pérez | Patricio Polic | Match Report | ||
| Second stage | 5 | Tue | 2016-04-12 | 19:30 | Huracán ar | 0–0 | uy Peñarol | Estadio Tomás Adolfo Ducó | Jhon Álvarez | Match Report | ||
| Second stage | 5 | Wed | 2016-04-13 | 17:15 | Cobresal cl | 2–0 | py Cerro Porteño | Estadio El Cobre | Raúl Orozco | Match Report | ||
| Second stage | 6 | Wed | 2016-04-13 | 17:30 | CS Emelec ec | 2–3 | mx UNAM | Estadio Jocay | Fernando Rapallini | Match Report | ||
| Second stage | 6 | Wed | 2016-04-13 | 18:30 | Olimpia py | 4–0 | ve Dep Táchira | Estadio Manuel Ferreira | Leandro Pedro Vuaden | Match Report | ||
| Second stage | 5 | Wed | 2016-04-13 | 19:30 | Racing Club ar | 0–1 | ar Boca Juniors | Estadio Presidente Juan Domingo Perón | Luis Cordero | Match Report | ||
| Second stage | 5 | Tue | 2016-04-12 | 19:45 | Sporting Cristal pe | 0–1 | co Nacional | Juan Soto | Match Report | |||
| Second stage | 5 | Tue | 2016-04-12 | 19:45 | Toluca mx | 2–1 | ar San Lorenzo | Estadio Nemesio Díez | Wilmar Roldán | Match Report | ||
| Second stage | 6 | Thu | 2016-04-14 | 19:30 | Colo-Colo cl | 0–0 | ec Independiente | Estadio Monumental David Arellano | Patricio Loustau | Match Report | ||
| Second stage | 6 | Thu | 2016-04-14 | 19:30 | Atlético Mineiro br | 4–0 | pe Melgar | Estádio Raimundo Sampaio | Jesús Valenzuela | Match Report | ||
| Second stage | 5 | Wed | 2016-04-13 | 19:45 | LDU de Quito ec | 2–3 | br Grêmio | Estadio de Liga Deportiva Universitaria | Roberto Tobar | Match Report | ||
| Second stage | 5 | Wed | 2016-04-13 | 21:45 | São Paulo br | 2–1 | ar River Plate | Estádio do Morumbi | Andrés Cunha | Match Report | ||
| Second stage | 5 | Thu | 2016-04-14 | 19:45 | AD Cali co | 1–1 | bo Bolívar | Estadio Deportivo Cali | Julio Quintana | Match Report | ||
| Second stage | 6 | Thu | 2016-04-14 | 21:45 | Palmeiras br | 4–0 | uy River Plate | Allianz Parque | Óscar Maldonado | Match Report | ||
| Second stage | 6 | Thu | 2016-04-14 | 21:45 | Nacional uy | 0–2 | ar Rosario Central | Estadio Gran Parque Central | Roberto García | Match Report | ||
| Second stage | 6 | Tue | 2016-04-19 | 17:30 | Nacional co | 0–0 | ar Huracán | Estadio Atanasio Girardot | Enrique Osses | Match Report | ||
| Second stage | 6 | Tue | 2016-04-19 | 19:30 | Peñarol uy | 4–3 | pe Sporting Cristal | Estadio Campeón del Siglo | Luiz Flavio De Oliveira | Match Report | ||
| Second stage | 6 | Wed | 2016-04-20 | 18:30 | Bolívar bo | 1–1 | ar Racing Club | Estadio Hernando Siles | Fernando Guerrero | Match Report | ||
| Second stage | 6 | Wed | 2016-04-20 | 19:30 | Boca Juniors ar | 6–2 | co AD Cali | Estadio Alberto José Armando | Christian Ferreyra | Match Report | ||
| Second stage | 6 | Tue | 2016-04-19 | 21:45 | San Lorenzo ar | 1–1 | ec LDU de Quito | Estadio Pedro Bidegaín | Ulises Mereles | Match Report | ||
| Second stage | 6 | Tue | 2016-04-19 | 21:45 | Grêmio br | 1–0 | mx Toluca | Arena do Grêmio | Gustavo Murillo | Match Report | ||
| Second stage | 6 | Wed | 2016-04-20 | 20:45 | Cerro Porteño py | 1–0 | co Santa Fe | Estadio Defensores del Chaco | Heber Roberto Lopes | Match Report | ||
| Second stage | 6 | Wed | 2016-04-20 | 21:45 | Corinthians br | 6–0 | cl Cobresal | Arena Corinthians | Klever Rojas | Match Report | ||
| Second stage | 6 | Thu | 2016-04-21 | 20:45 | The Strongest bo | 1–1 | br São Paulo | Estadio Hernando Siles | Roberto Tobar | Match Report | ||
| Second stage | 6 | Thu | 2016-04-21 | 21:45 | River Plate ar | 4–3 | ve Trujillanos | Estadio Monumental Antonio Vespucio Libe... | Víctor Carrillo | Match Report | ||
| Round of 16 | Tue | 2016-04-26 | 19:30 | Huracán ar | 0–0 | co Nacional | Estadio Tomás Adolfo Ducó | Patricio Polic | Match Report | Leg 1 of 2 | ||
| Round of 16 | Wed | 2016-04-27 | 19:30 | Racing Club ar | 0–0 | br Atlético Mineiro | Estadio Presidente Juan Domingo Perón | Julio Quintana | Match Report | Leg 1 of 2 | ||
| Round of 16 | Tue | 2016-04-26 | 20:15 | Dep Táchira ve | 1–0 | mx UNAM | Estadio Polideportivo de Pueblo Nuevo | Óscar Maldonado | Match Report | Leg 1 of 2 | ||
| Round of 16 | Thu | 2016-04-28 | 17:30 | Independiente ec | 2–0 | ar River Plate | Estadio General Rumiñahui del Valle de L... | Heber Roberto Lopes | Match Report | Leg 1 of 2 | ||
| Round of 16 | Wed | 2016-04-27 | 21:45 | Grêmio br | 0–1 | ar Rosario Central | Arena do Grêmio | Víctor Carrillo | Match Report | Leg 1 of 2 | ||
| Round of 16 | Wed | 2016-04-27 | 21:45 | Nacional uy | 0–0 | br Corinthians | Estadio Gran Parque Central | Patricio Loustau | Match Report | Leg 1 of 2 | ||
| Round of 16 | Thu | 2016-04-28 | 20:45 | Cerro Porteño py | 1–2 | ar Boca Juniors | Estadio Defensores del Chaco | Francisco Chacon | Match Report | Leg 1 of 2 | ||
| Round of 16 | Thu | 2016-04-28 | 21:45 | São Paulo br | 4–0 | mx Toluca | Estádio do Morumbi | Jonathan Fuentes | Match Report | Leg 1 of 2 | ||
| Round of 16 | Wed | 2016-05-04 | 17:15 | Toluca mx | 3–1 | br São Paulo | Estadio Nemesio Díez | Wilson Lamouroux | Match Report | Leg 2 of 2; São Paulo won | ||
| Round of 16 | Wed | 2016-05-04 | 19:15 | River Plate ar | 1–0 | ec Independiente | Estadio Monumental Antonio Vespucio Libe... | Wilmar Roldán | Match Report | Leg 2 of 2; Independiente won | ||
| Round of 16 | Tue | 2016-05-03 | 19:45 | Nacional co | 4–2 | ar Huracán | Estadio Atanasio Girardot | José Argote | Match Report | Leg 2 of 2; Nacional won | ||
| Round of 16 | Tue | 2016-05-03 | 21:45 | UNAM mx | 2–0 | ve Dep Táchira | Estadio Olímpico de Universitario | Patricio Polic | Match Report | Leg 2 of 2; UNAM won | ||
| Round of 16 | Thu | 2016-05-05 | 19:15 | Rosario Central ar | 3–0 | br Grêmio | Estadio Dr. Lisandro de la Torre | Enrique Cáceres | Match Report | Leg 2 of 2; Rosario Central won | ||
| Round of 16 | Wed | 2016-05-04 | 21:45 | Corinthians br | 2–2 | uy Nacional | Arena Corinthians | Néstor Pitana | Match Report | Leg 2 of 2; Nacional won | ||
| Round of 16 | Wed | 2016-05-04 | 21:45 | Atlético Mineiro br | 2–1 | ar Racing Club | Estádio Raimundo Sampaio | Daniel Fedorczuk | Match Report | Leg 2 of 2; Atlético Mineiro won | ||
| Round of 16 | Thu | 2016-05-05 | 21:45 | Boca Juniors ar | 3–1 | py Cerro Porteño | Estadio Alberto José Armando | Wilton Sampaio | Match Report | Leg 2 of 2; Boca Juniors won | ||
| Quarter-finals | Thu | 2016-05-12 | 19:30 | Nacional uy | 1–1 | ar Boca Juniors | Estadio Gran Parque Central | Enrique Cáceres | Match Report | Leg 1 of 2 | ||
| Quarter-finals | Wed | 2016-05-11 | 21:45 | São Paulo br | 1–0 | br Atlético Mineiro | Estádio do Morumbi | Wilmar Roldán | Match Report | Leg 1 of 2 | ||
| Quarter-finals | Thu | 2016-05-12 | 21:45 | Rosario Central ar | 1–0 | co Nacional | Estadio Dr. Lisandro de la Torre | Sandro Ricci | Match Report | Leg 1 of 2 | ||
| Quarter-finals | Tue | 2016-05-17 | 19:45 | Independiente ec | 2–1 | mx UNAM | Estadio Olímpico Atahualpa | Mauro Vigliano | Match Report | Leg 1 of 2 | ||
| Quarter-finals | Thu | 2016-05-19 | 20:15 | Boca Juniors ar | (4) 1–1 (3) | uy Nacional | Estadio Alberto José Armando | Heber Roberto Lopes | Match Report | Leg 2 of 2; Boca Juniors won; Boca Juniors won on penalty kicks following extra time | ||
| Quarter-finals | Wed | 2016-05-18 | 21:45 | Atlético Mineiro br | 2–1 | br São Paulo | Estádio Raimundo Sampaio | Andrés Cunha | Match Report | Leg 2 of 2; São Paulo won | ||
| Quarter-finals | Thu | 2016-05-19 | 20:45 | Nacional co | 3–1 | ar Rosario Central | Estadio Atanasio Girardot | Daniel Fedorczuk | Match Report | Leg 2 of 2; Nacional won | ||
| Quarter-finals | Tue | 2016-05-24 | 19:45 | UNAM mx | (3) 2–1 (5) | ec Independiente | Estadio Olímpico de Universitario | Víctor Carrillo | Match Report | Leg 2 of 2; Independiente won; Independiente won on penalty kicks following extra time | ||
| Semi-finals | Wed | 2016-07-06 | 21:45 | São Paulo br | 0–2 | co Nacional | Estádio do Morumbi | Mauro Vigliano | Match Report | Leg 1 of 2 | ||
| Round | Wk | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
| Semi-finals | Thu | 2016-07-07 | 19:45 | Independiente ec | 2–1 | ar Boca Juniors | Estadio Olímpico Atahualpa | Wilmar Roldán | Match Report | Leg 1 of 2 | ||
| Semi-finals | Wed | 2016-07-13 | 19:45 | Nacional co | 2–1 | br São Paulo | Estadio Atanasio Girardot | Patricio Polic | Match Report | Leg 2 of 2; Nacional won | ||
| Semi-finals | Thu | 2016-07-14 | 21:45 | Boca Juniors ar | 2–3 | ec Independiente | Estadio Alberto José Armando | Daniel Fedorczuk | Match Report | Leg 2 of 2; Independiente won | ||
| Finals | Wed | 2016-07-20 | 19:45 | Independiente ec | 1–1 | co Nacional | Estadio Olímpico Atahualpa | Enrique Cáceres | Match Report | Leg 1 of 2 | ||
| Finals | Wed | 2016-07-27 | 19:45 | Nacional co | 1–0 | ec Independiente | Estadio Atanasio Girardot | Néstor Pitana | Match Report | Leg 2 of 2; Nacional won |
| Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Tue | 2016-02-02 | 19:30 | Huracán ar | 1–0 | ve Caracas | Estadio Tomás Adolfo Ducó | Patricio Polic | Match Report | Leg 1 of 2 | |
| Wed | 2016-02-03 | 18:45 | U César Vallejo pe | 1–1 | br São Paulo | Estadio Mansiche | Roddy Zambrano | Match Report | Leg 1 of 2 | |
| Tue | 2016-02-02 | 21:45 | River Plate uy | 2–0 | cl U de Chile | Parque Federico Omar Saroldi | Patricio Loustau | Match Report | Leg 1 of 2 | |
| Thu | 2016-02-04 | 17:30 | Independiente ec | 1–0 | py Guaraní | Estadio General Rumiñahui del Valle de L... | Juan Soto | Match Report | Leg 1 of 2 | |
| Wed | 2016-02-03 | 20:15 | Puebla mx | 2–2 | ar Racing Club | Estadio Cuauhtémoc | Daniel Fedorczuk | Match Report | Leg 1 of 2 | |
| Thu | 2016-02-04 | 20:45 | Oriente Petrolero bo | 1–3 | co Santa Fe | Estadio Ramón Aguilera Costas | Pericles Bassols Pegado Cortez | Match Report | Leg 1 of 2 | |
| Tue | 2016-02-09 | 19:30 | U de Chile cl | 0–0 | uy River Plate | Estadio Nacional Julio Martínez Prádanos | Carlos Vera | Match Report | Leg 2 of 2; River Plate won | |
| Tue | 2016-02-09 | 20:15 | Caracas ve | 2–1 | ar Huracán | Estadio Olímpico | Enrique Cáceres | Match Report | Leg 2 of 2; Huracán won | |
| Wed | 2016-02-10 | 21:45 | São Paulo br | 1–0 | pe U César Vallejo | Estádio do Pacaembú | Christian Ferreyra | Match Report | Leg 2 of 2; São Paulo won | |
| Thu | 2016-02-11 | 19:30 | Guaraní py | 2–1 | ec Independiente | Estadio Defensores del Chaco | Mauro Vigliano | Match Report | Leg 2 of 2; Independiente won | |
| Wed | 2016-02-10 | 21:45 | Racing Club ar | 1–0 | mx Puebla | Estadio Presidente Juan Domingo Perón | Ricardo Marques Ribeiro | Match Report | Leg 2 of 2; Racing Club won | |
| Thu | 2016-02-11 | 20:00 | Santa Fe co | 3–0 | bo Oriente Petrolero | Estadio Nemesio Camacho El Campín | Víctor Carrillo | Match Report | Leg 2 of 2; Santa Fe won |
| Round | Wk | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Second stage | 1 | Tue | 2016-02-16 | 20:45 | River Plate uy | 2–2 | br Palmeiras | Parque Federico Omar Saroldi | Julio Bascuñán | Match Report | ||
| Second stage | 1 | Wed | 2016-02-17 | 18:45 | Melgar pe | 1–2 | br Atlético Mineiro | Estadio de la Universidad Nacional San A... | Wilson Lamouroux | Match Report | ||
| Second stage | 1 | Wed | 2016-02-17 | 19:30 | São Paulo br | 0–1 | bo The Strongest | Estádio do Pacaembú | Mario Díaz de Vivar | Match Report | ||
| Second stage | 1 | Wed | 2016-02-17 | 20:45 | Cobresal cl | 0–1 | br Corinthians | Estadio El Cobre | Andrés Cunha | Match Report | ||
| Second stage | 1 | Tue | 2016-02-16 | 21:00 | Santa Fe co | 0–0 | py Cerro Porteño | Estadio Nemesio Camacho El Campín | Roberto García | Match Report | ||
| Second stage | 1 | Tue | 2016-02-16 | 21:30 | Dep Táchira ve | 2–1 | py Olimpia | Estadio Polideportivo de Pueblo Nuevo | Heber Roberto Lopes | Match Report | ||
| Second stage | 1 | Wed | 2016-02-17 | 20:00 | Toluca mx | 2–0 | br Grêmio | Estadio Nemesio Díez | Gery Vargas | Match Report | ||
| Second stage | 1 | Thu | 2016-02-18 | 19:45 | Sporting Cristal pe | 1–1 | uy Peñarol | Estadio Alberto Gallardo | Wilton Sampaio | Match Report | ||
| Second stage | 1 | Thu | 2016-02-18 | 19:45 | Independiente ec | 1–1 | cl Colo-Colo | Estadio General Rumiñahui del Valle de L... | José Argote | Match Report | ||
| Second stage | 1 | Thu | 2016-02-18 | 21:00 | UNAM mx | 4–2 | ec CS Emelec | Estadio Olímpico de Universitario | Diego Haro | Match Report | ||
| Second stage | 1 | Tue | 2016-02-23 | 17:30 | LDU de Quito ec | 2–0 | ar San Lorenzo | Jonathan Fuentes | Match Report | |||
| Second stage | 1 | Wed | 2016-02-24 | 19:30 | Racing Club ar | 4–1 | bo Bolívar | Estadio Presidente Juan Domingo Perón | Ulises Mereles | Match Report | ||
| Second stage | 2 | Wed | 2016-02-24 | 19:30 | Colo-Colo cl | 1–0 | pe Melgar | Estadio Monumental David Arellano | Julio Quintana | Match Report | ||
| Second stage | 1 | Tue | 2016-02-23 | 21:45 | Huracán ar | 0–2 | co Nacional | Estadio Tomás Adolfo Ducó | Roberto Tobar | Match Report | ||
| Second stage | 1 | Thu | 2016-02-25 | 19:30 | Rosario Central ar | 1–1 | uy Nacional | Estadio Dr. Lisandro de la Torre | Wilmar Roldán | Match Report | ||
| Second stage | 2 | Thu | 2016-02-25 | 19:30 | Cerro Porteño py | 2–1 | cl Cobresal | Estadio Defensores del Chaco | Néstor Pitana | Match Report | ||
| Second stage | 1 | Wed | 2016-02-24 | 19:45 | AD Cali co | 0–0 | ar Boca Juniors | Estadio Deportivo Cali | Pericles Bassols Pegado Cortez | Match Report | ||
| Second stage | 2 | Wed | 2016-02-24 | 21:45 | Atlético Mineiro br | 1–0 | ec Independiente | Estádio Raimundo Sampaio | Fernando Rapallini | Match Report | ||
| Second stage | 2 | Thu | 2016-02-25 | 19:45 | CS Emelec ec | 2–0 | ve Dep Táchira | Estadio Banco del Pacífico | Raúl Orozco | Match Report | ||
| Second stage | 1 | Thu | 2016-02-25 | 20:15 | Trujillanos ve | 0–4 | ar River Plate | Estadio José Alberto Pérez | Juan Bravo | Match Report | ||
| Second stage | 3 | Tue | 2016-03-01 | 15:15 | Melgar pe | 0–1 | ec Independiente | Estadio Mariano Melgar | Óscar Rojas | Match Report | ||
| Second stage | 2 | Tue | 2016-03-01 | 19:30 | Olimpia py | 0–2 | mx UNAM | Estadio Manuel Ferreira | Germán Delfino | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 16:15 | The Strongest bo | 2–1 | ve Trujillanos | Estadio Hernando Siles | Gustavo Murillo | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 19:30 | Nacional uy | 0–0 | uy River Plate | Estadio Gran Parque Central | Víctor Carrillo | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 19:30 | San Lorenzo ar | 1–1 | mx Toluca | Estadio Pedro Bidegaín | Enrique Osses | Match Report | ||
| Second stage | 2 | Tue | 2016-03-01 | 19:45 | Nacional co | 3–0 | pe Sporting Cristal | Estadio Atanasio Girardot | Óscar Maldonado | Match Report | ||
| Second stage | 2 | Tue | 2016-03-01 | 21:45 | Peñarol uy | 0–1 | ar Huracán | Estadio Centenario | César Arturo Ramos | Match Report | ||
| Second stage | 2 | Thu | 2016-03-03 | 19:30 | Boca Juniors ar | 0–0 | ar Racing Club | Estadio Alberto José Armando | Sandro Ricci | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 21:45 | Grêmio br | 4–0 | ec LDU de Quito | Arena do Grêmio | Jesús Valenzuela | Match Report | ||
| Second stage | 2 | Wed | 2016-03-02 | 21:45 | Corinthians br | 1–0 | co Santa Fe | Arena Corinthians | Mauro Vigliano | Match Report | ||
| Second stage | 2 | Thu | 2016-03-03 | 20:45 | Bolívar bo | 5–0 | co AD Cali | Estadio Hernando Siles | Klever Rojas | Match Report | ||
| Second stage | 2 | Thu | 2016-03-03 | 21:45 | Palmeiras br | 2–0 | ar Rosario Central | Allianz Parque | Enrique Cáceres | Match Report | ||
| Second stage | 3 | Tue | 2016-03-08 | 17:30 | CS Emelec ec | 2–2 | py Olimpia | Estadio Reales Tamarindos | Wilton Sampaio | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 17:15 | Cobresal cl | 1–2 | co Santa Fe | Estadio El Cobre | Juan Bravo | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 19:30 | Cerro Porteño py | 3–2 | br Corinthians | Estadio Defensores del Chaco | Diego Haro | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 19:30 | Rosario Central ar | 4–1 | uy River Plate | Estadio Dr. Lisandro de la Torre | Ulises Mereles | Match Report | ||
| Second stage | 3 | Tue | 2016-03-08 | 19:45 | Nacional co | 2–0 | uy Peñarol | Estadio Atanasio Girardot | Heber Roberto Lopes | Match Report | ||
| Second stage | 3 | Tue | 2016-03-08 | 19:45 | Sporting Cristal pe | 3–2 | ar Huracán | Estadio Alberto Gallardo | Mario Díaz de Vivar | Match Report | ||
| Second stage | 2 | Thu | 2016-03-10 | 19:30 | River Plate ar | 1–1 | br São Paulo | Estadio Monumental Antonio Vespucio Libe... | Julio Bascuñán | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 20:15 | Dep Táchira ve | 2–0 | mx UNAM | Estadio Polideportivo de Pueblo Nuevo | Jorge Baliño | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 21:45 | Grêmio br | 1–1 | ar San Lorenzo | Arena do Grêmio | Daniel Fedorczuk | Match Report | ||
| Second stage | 3 | Wed | 2016-03-09 | 21:45 | Palmeiras br | 1–2 | uy Nacional | Allianz Parque | Enrique Osses | Match Report | ||
| Second stage | 3 | Thu | 2016-03-10 | 19:45 | LDU de Quito ec | 1–2 | mx Toluca | Estadio de Liga Deportiva Universitaria | Wilson Lamouroux | Match Report | ||
| Second stage | 3 | Thu | 2016-03-10 | 20:45 | Bolívar bo | 1–1 | ar Boca Juniors | Estadio Hernando Siles | Andrés Cunha | Match Report | ||
| Second stage | 3 | Thu | 2016-03-10 | 21:45 | Colo-Colo cl | 0–0 | br Atlético Mineiro | Estadio Monumental David Arellano | Gery Vargas | Match Report | ||
| Second stage | 4 | Tue | 2016-03-15 | 17:30 | Independiente ec | 2–0 | pe Melgar | Estadio General Rumiñahui del Valle de L... | Raúl Orozco | Match Report | ||
| Second stage | 4 | Tue | 2016-03-15 | 17:30 | Santa Fe co | 3–0 | cl Cobresal | Estadio Nemesio Camacho El Campín | Óscar Maldonado | Match Report | ||
| Second stage | 3 | Wed | 2016-03-16 | 18:00 | Trujillanos ve | 1–1 | br São Paulo | Estadio José Alberto Pérez | Wilson Lamouroux | Match Report | ||
| Second stage | 3 | Wed | 2016-03-16 | 18:30 | The Strongest bo | 1–1 | ar River Plate | Estadio Hernando Siles | Julio Quintana | Match Report | ||
| Second stage | 4 | Tue | 2016-03-15 | 21:45 | San Lorenzo ar | 1–1 | br Grêmio | Estadio Pedro Bidegaín | Andrés Cunha | Match Report | ||
| Second stage | 4 | Tue | 2016-03-15 | 21:45 | Peñarol uy | 0–4 | co Nacional | Estadio Centenario | Julio Bascuñán | Match Report | ||
| Second stage | 4 | Thu | 2016-03-17 | 19:30 | Olimpia py | 4–2 | ec CS Emelec | Estadio Defensores del Chaco | Darío Herrera | Match Report | ||
| Second stage | 4 | Thu | 2016-03-17 | 19:30 | River Plate uy | 1–3 | ar Rosario Central | Estadio Centenario | José Argote | Match Report | ||
| Second stage | 4 | Wed | 2016-03-16 | 21:45 | Corinthians br | 2–0 | py Cerro Porteño | Arena Corinthians | Patricio Loustau | Match Report | ||
| Second stage | 4 | Wed | 2016-03-16 | 21:45 | Atlético Mineiro br | 3–0 | cl Colo-Colo | Estádio Raimundo Sampaio | Juan Soto | Match Report | ||
| Second stage | 3 | Thu | 2016-03-17 | 19:45 | AD Cali co | 2–2 | ar Racing Club | Estadio Deportivo Cali | Diego Haro | Match Report | ||
| Second stage | 4 | Thu | 2016-03-17 | 21:00 | UNAM mx | 4–1 | ve Dep Táchira | Estadio Olímpico Universitario de Colima | Ricardo Marques Ribeiro | Match Report | ||
| Second stage | 4 | Thu | 2016-03-17 | 21:45 | Nacional uy | 1–0 | br Palmeiras | Estadio Gran Parque Central | Luis Cordero | Match Report | ||
| Second stage | 5 | Tue | 2016-04-05 | 18:00 | Dep Táchira ve | 1–0 | ec CS Emelec | Estadio Polideportivo de Pueblo Nuevo | Christian Ferreyra | Match Report | ||
| Second stage | 4 | Tue | 2016-04-05 | 19:30 | Huracán ar | 4–2 | pe Sporting Cristal | Estadio Tomás Adolfo Ducó | Raphael Claus | Match Report | ||
| Second stage | 4 | Wed | 2016-04-06 | 19:30 | River Plate ar | 6–0 | bo The Strongest | Estadio Monumental Antonio Vespucio Libe... | Wilson Lamouroux | Match Report | ||
| Second stage | 4 | Tue | 2016-04-05 | 19:45 | Toluca mx | 2–1 | ec LDU de Quito | Estadio Nemesio Díez | José Argote | Match Report | ||
| Second stage | 4 | Tue | 2016-04-05 | 21:45 | São Paulo br | 6–0 | ve Trujillanos | Estádio do Morumbi | Ulises Mereles | Match Report | ||
| Second stage | 4 | Thu | 2016-04-07 | 19:30 | Boca Juniors ar | 3–1 | bo Bolívar | Estadio Alberto José Armando | Víctor Carrillo | Match Report | ||
| Second stage | 5 | Thu | 2016-04-07 | 19:30 | River Plate uy | 2–2 | uy Nacional | Estadio Centenario | Enrique Cáceres | Match Report | ||
| Second stage | 5 | Wed | 2016-04-06 | 19:45 | Santa Fe co | 1–1 | br Corinthians | Estadio Nemesio Camacho El Campín | Néstor Pitana | Match Report | ||
| Second stage | 5 | Wed | 2016-04-06 | 19:45 | Independiente ec | 3–2 | br Atlético Mineiro | Estadio General Rumiñahui del Valle de L... | Darío Herrera | Match Report | ||
| Second stage | 5 | Wed | 2016-04-06 | 21:45 | Rosario Central ar | 3–3 | br Palmeiras | Estadio Dr. Lisandro de la Torre | Juan Bravo | Match Report | ||
| Second stage | 5 | Wed | 2016-04-06 | 22:00 | UNAM mx | 4–1 | py Olimpia | Estadio Olímpico de Universitario | Julio Bascuñán | Match Report | ||
| Second stage | 5 | Thu | 2016-04-07 | 19:45 | Melgar pe | 1–2 | cl Colo-Colo | Estadio de la Universidad Nacional San A... | Luis Sánchez | Match Report | ||
| Second stage | 4 | Thu | 2016-04-07 | 21:45 | Racing Club ar | 4–2 | co AD Cali | Estadio Presidente Juan Domingo Perón | Heber Roberto Lopes | Match Report | ||
| Second stage | 5 | Tue | 2016-04-12 | 18:00 | Trujillanos ve | 2–1 | bo The Strongest | Estadio José Alberto Pérez | Patricio Polic | Match Report | ||
| Second stage | 5 | Tue | 2016-04-12 | 19:30 | Huracán ar | 0–0 | uy Peñarol | Estadio Tomás Adolfo Ducó | Jhon Álvarez | Match Report | ||
| Second stage | 5 | Wed | 2016-04-13 | 17:15 | Cobresal cl | 2–0 | py Cerro Porteño | Estadio El Cobre | Raúl Orozco | Match Report | ||
| Second stage | 6 | Wed | 2016-04-13 | 17:30 | CS Emelec ec | 2–3 | mx UNAM | Estadio Jocay | Fernando Rapallini | Match Report | ||
| Second stage | 6 | Wed | 2016-04-13 | 18:30 | Olimpia py | 4–0 | ve Dep Táchira | Estadio Manuel Ferreira | Leandro Pedro Vuaden | Match Report | ||
| Second stage | 5 | Wed | 2016-04-13 | 19:30 | Racing Club ar | 0–1 | ar Boca Juniors | Estadio Presidente Juan Domingo Perón | Luis Cordero | Match Report | ||
| Second stage | 5 | Tue | 2016-04-12 | 19:45 | Sporting Cristal pe | 0–1 | co Nacional | Juan Soto | Match Report | |||
| Second stage | 5 | Tue | 2016-04-12 | 19:45 | Toluca mx | 2–1 | ar San Lorenzo | Estadio Nemesio Díez | Wilmar Roldán | Match Report | ||
| Second stage | 6 | Thu | 2016-04-14 | 19:30 | Atlético Mineiro br | 4–0 | pe Melgar | Estádio Raimundo Sampaio | Jesús Valenzuela | Match Report | ||
| Second stage | 6 | Thu | 2016-04-14 | 19:30 | Colo-Colo cl | 0–0 | ec Independiente | Estadio Monumental David Arellano | Patricio Loustau | Match Report | ||
| Second stage | 5 | Wed | 2016-04-13 | 19:45 | LDU de Quito ec | 2–3 | br Grêmio | Estadio de Liga Deportiva Universitaria | Roberto Tobar | Match Report | ||
| Second stage | 5 | Wed | 2016-04-13 | 21:45 | São Paulo br | 2–1 | ar River Plate | Estádio do Morumbi | Andrés Cunha | Match Report | ||
| Second stage | 5 | Thu | 2016-04-14 | 19:45 | AD Cali co | 1–1 | bo Bolívar | Estadio Deportivo Cali | Julio Quintana | Match Report | ||
| Second stage | 6 | Thu | 2016-04-14 | 21:45 | Nacional uy | 0–2 | ar Rosario Central | Estadio Gran Parque Central | Roberto García | Match Report | ||
| Second stage | 6 | Thu | 2016-04-14 | 21:45 | Palmeiras br | 4–0 | uy River Plate | Allianz Parque | Óscar Maldonado | Match Report | ||
| Second stage | 6 | Tue | 2016-04-19 | 17:30 | Nacional co | 0–0 | ar Huracán | Estadio Atanasio Girardot | Enrique Osses | Match Report | ||
| Second stage | 6 | Tue | 2016-04-19 | 19:30 | Peñarol uy | 4–3 | pe Sporting Cristal | Estadio Campeón del Siglo | Luiz Flavio De Oliveira | Match Report | ||
| Second stage | 6 | Wed | 2016-04-20 | 18:30 | Bolívar bo | 1–1 | ar Racing Club | Estadio Hernando Siles | Fernando Guerrero | Match Report | ||
| Second stage | 6 | Wed | 2016-04-20 | 19:30 | Boca Juniors ar | 6–2 | co AD Cali | Estadio Alberto José Armando | Christian Ferreyra | Match Report | ||
| Second stage | 6 | Tue | 2016-04-19 | 21:45 | Grêmio br | 1–0 | mx Toluca | Arena do Grêmio | Gustavo Murillo | Match Report | ||
| Second stage | 6 | Tue | 2016-04-19 | 21:45 | San Lorenzo ar | 1–1 | ec LDU de Quito | Estadio Pedro Bidegaín | Ulises Mereles | Match Report | ||
| Second stage | 6 | Wed | 2016-04-20 | 20:45 | Cerro Porteño py | 1–0 | co Santa Fe | Estadio Defensores del Chaco | Heber Roberto Lopes | Match Report | ||
| Second stage | 6 | Wed | 2016-04-20 | 21:45 | Corinthians br | 6–0 | cl Cobresal | Arena Corinthians | Klever Rojas | Match Report | ||
| Second stage | 6 | Thu | 2016-04-21 | 20:45 | The Strongest bo | 1–1 | br São Paulo | Estadio Hernando Siles | Roberto Tobar | Match Report | ||
| Second stage | 6 | Thu | 2016-04-21 | 21:45 | River Plate ar | 4–3 | ve Trujillanos | Estadio Monumental Antonio Vespucio Libe... | Víctor Carrillo | Match Report |
| Round | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Round of 16 | Tue | 2016-04-26 | 19:30 | Huracán ar | 0–0 | co Nacional | Estadio Tomás Adolfo Ducó | Patricio Polic | Match Report | Leg 1 of 2 | |
| Round of 16 | Wed | 2016-04-27 | 19:30 | Racing Club ar | 0–0 | br Atlético Mineiro | Estadio Presidente Juan Domingo Perón | Julio Quintana | Match Report | Leg 1 of 2 | |
| Round of 16 | Tue | 2016-04-26 | 20:15 | Dep Táchira ve | 1–0 | mx UNAM | Estadio Polideportivo de Pueblo Nuevo | Óscar Maldonado | Match Report | Leg 1 of 2 | |
| Round of 16 | Thu | 2016-04-28 | 17:30 | Independiente ec | 2–0 | ar River Plate | Estadio General Rumiñahui del Valle de L... | Heber Roberto Lopes | Match Report | Leg 1 of 2 | |
| Round of 16 | Wed | 2016-04-27 | 21:45 | Grêmio br | 0–1 | ar Rosario Central | Arena do Grêmio | Víctor Carrillo | Match Report | Leg 1 of 2 | |
| Round of 16 | Wed | 2016-04-27 | 21:45 | Nacional uy | 0–0 | br Corinthians | Estadio Gran Parque Central | Patricio Loustau | Match Report | Leg 1 of 2 | |
| Round of 16 | Thu | 2016-04-28 | 20:45 | Cerro Porteño py | 1–2 | ar Boca Juniors | Estadio Defensores del Chaco | Francisco Chacon | Match Report | Leg 1 of 2 | |
| Round of 16 | Thu | 2016-04-28 | 21:45 | São Paulo br | 4–0 | mx Toluca | Estádio do Morumbi | Jonathan Fuentes | Match Report | Leg 1 of 2 | |
| Round of 16 | Wed | 2016-05-04 | 17:15 | Toluca mx | 3–1 | br São Paulo | Estadio Nemesio Díez | Wilson Lamouroux | Match Report | Leg 2 of 2; São Paulo won | |
| Round of 16 | Wed | 2016-05-04 | 19:15 | River Plate ar | 1–0 | ec Independiente | Estadio Monumental Antonio Vespucio Libe... | Wilmar Roldán | Match Report | Leg 2 of 2; Independiente won | |
| Round of 16 | Tue | 2016-05-03 | 19:45 | Nacional co | 4–2 | ar Huracán | Estadio Atanasio Girardot | José Argote | Match Report | Leg 2 of 2; Nacional won | |
| Round of 16 | Tue | 2016-05-03 | 21:45 | UNAM mx | 2–0 | ve Dep Táchira | Estadio Olímpico de Universitario | Patricio Polic | Match Report | Leg 2 of 2; UNAM won | |
| Round of 16 | Thu | 2016-05-05 | 19:15 | Rosario Central ar | 3–0 | br Grêmio | Estadio Dr. Lisandro de la Torre | Enrique Cáceres | Match Report | Leg 2 of 2; Rosario Central won | |
| Round of 16 | Wed | 2016-05-04 | 21:45 | Atlético Mineiro br | 2–1 | ar Racing Club | Estádio Raimundo Sampaio | Daniel Fedorczuk | Match Report | Leg 2 of 2; Atlético Mineiro won | |
| Round of 16 | Wed | 2016-05-04 | 21:45 | Corinthians br | 2–2 | uy Nacional | Arena Corinthians | Néstor Pitana | Match Report | Leg 2 of 2; Nacional won | |
| Round of 16 | Thu | 2016-05-05 | 21:45 | Boca Juniors ar | 3–1 | py Cerro Porteño | Estadio Alberto José Armando | Wilton Sampaio | Match Report | Leg 2 of 2; Boca Juniors won | |
| Quarter-finals | Thu | 2016-05-12 | 19:30 | Nacional uy | 1–1 | ar Boca Juniors | Estadio Gran Parque Central | Enrique Cáceres | Match Report | Leg 1 of 2 | |
| Quarter-finals | Wed | 2016-05-11 | 21:45 | São Paulo br | 1–0 | br Atlético Mineiro | Estádio do Morumbi | Wilmar Roldán | Match Report | Leg 1 of 2 | |
| Quarter-finals | Thu | 2016-05-12 | 21:45 | Rosario Central ar | 1–0 | co Nacional | Estadio Dr. Lisandro de la Torre | Sandro Ricci | Match Report | Leg 1 of 2 | |
| Quarter-finals | Tue | 2016-05-17 | 19:45 | Independiente ec | 2–1 | mx UNAM | Estadio Olímpico Atahualpa | Mauro Vigliano | Match Report | Leg 1 of 2 | |
| Quarter-finals | Thu | 2016-05-19 | 20:15 | Boca Juniors ar | (4) 1–1 (3) | uy Nacional | Estadio Alberto José Armando | Heber Roberto Lopes | Match Report | Leg 2 of 2; Boca Juniors won; Boca Juniors won on penalty kicks following extra time | |
| Quarter-finals | Wed | 2016-05-18 | 21:45 | Atlético Mineiro br | 2–1 | br São Paulo | Estádio Raimundo Sampaio | Andrés Cunha | Match Report | Leg 2 of 2; São Paulo won | |
| Quarter-finals | Thu | 2016-05-19 | 20:45 | Nacional co | 3–1 | ar Rosario Central | Estadio Atanasio Girardot | Daniel Fedorczuk | Match Report | Leg 2 of 2; Nacional won | |
| Quarter-finals | Tue | 2016-05-24 | 19:45 | UNAM mx | (3) 2–1 (5) | ec Independiente | Estadio Olímpico de Universitario | Víctor Carrillo | Match Report | Leg 2 of 2; Independiente won; Independiente won on penalty kicks following extra time | |
| Semi-finals | Wed | 2016-07-06 | 21:45 | São Paulo br | 0–2 | co Nacional | Estádio do Morumbi | Mauro Vigliano | Match Report | Leg 1 of 2 | |
| Semi-finals | Thu | 2016-07-07 | 19:45 | Independiente ec | 2–1 | ar Boca Juniors | Estadio Olímpico Atahualpa | Wilmar Roldán | Match Report | Leg 1 of 2 | |
| Semi-finals | Wed | 2016-07-13 | 19:45 | Nacional co | 2–1 | br São Paulo | Estadio Atanasio Girardot | Patricio Polic | Match Report | Leg 2 of 2; Nacional won | |
| Semi-finals | Thu | 2016-07-14 | 21:45 | Boca Juniors ar | 2–3 | ec Independiente | Estadio Alberto José Armando | Daniel Fedorczuk | Match Report | Leg 2 of 2; Independiente won | |
| Finals | Wed | 2016-07-20 | 19:45 | Independiente ec | 1–1 | co Nacional | Estadio Olímpico Atahualpa | Enrique Cáceres | Match Report | Leg 1 of 2 | |
| Finals | Wed | 2016-07-27 | 19:45 | Nacional co | 1–0 | ec Independiente | Estadio Atanasio Girardot | Néstor Pitana | Match Report | Leg 2 of 2; Nacional won |
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