Ergebnisse & Spiele 2021 Major League Soccer
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa. | 17.04.2021 | 14:00 | CF Montréal | 1.3 | 4–2 | 2.0 | Toronto FC | DRV PNK Stadium | Ismail Elfath | Spielbericht | ||
| Sa. | 17.04.2021 | 15:00 | LAFC | 3.2 | 2–0 | 0.8 | Austin | 4.900 | Banc of California Stadium | Alex Chilowicz | Spielbericht | |
| Sa. | 17.04.2021 | 15:00 | Orlando City | 1.4 | 0–0 | 1.2 | Atlanta Utd | 11.503 | Exploria Stadium | Jair Marrufo | Spielbericht | |
| Fr. | 16.04.2021 | 18:30 | Seattle Sounders | 3.2 | 4–0 | 1.3 | Minnesota Utd | 7.042 | Lumen Field | Joe Dickerson | Spielbericht | |
| Fr. | 16.04.2021 | 19:00 | Houston Dynamo | 1.7 | 2–1 | 1.2 | SJ Earthquakes | BBVA Stadium | Armando Villarreal | Spielbericht | ||
| So. | 18.04.2021 | 15:00 | Inter Miami | 2.9 | 2–3 | 1.7 | LA Galaxy | DRV PNK Stadium | Chris Penso | Spielbericht | ||
| So. | 18.04.2021 | 17:30 | Columbus Crew | 1.1 | 0–0 | 1.3 | Philadelphia Union | 5.180 | MAPFRE Stadium | Ramy Touchan | Spielbericht | |
| Sa. | 17.04.2021 | 19:00 | FC Dallas | 0.9 | 0–0 | 1.0 | Colorado Rapids | 8.621 | Toyota Stadium | Nima Saghafi | Spielbericht | |
| Sa. | 17.04.2021 | 19:30 | Nashville SC | 3.7 | 2–2 | 2.1 | FC Cincinnati | Nissan Stadium | Rubiel Vazquez | Spielbericht | ||
| Sa. | 17.04.2021 | 19:30 | Chicago Fire | 2.2 | 2–2 | 2.0 | NE Revolution | Soldier Field | Fotis Bazakos | Spielbericht | ||
| Sa. | 17.04.2021 | 20:00 | NY Red Bulls | 0.9 | 1–2 | 2.0 | Sporting KC | Red Bull Arena | Robert Sibiga | Spielbericht | ||
| Sa. | 17.04.2021 | 20:00 | D.C. United | 0.6 | 2–1 | 1.0 | NYCFC | 4.500 | Audi Field | Ted Unkel | Spielbericht | |
| So. | 18.04.2021 | 20:00 | Vancouver W'caps | 0.5 | 1–0 | 1.2 | Portland Timbers | Rio Tinto Stadium | Allen Chapman | Spielbericht | ||
| Fr. | 23.04.2021 | 18:30 | Sporting KC | 0.6 | 1–1 | 1.1 | Orlando City | Children's Mercy Park | Joe Dickerson | Spielbericht | ||
| Sa. | 24.04.2021 | 12:30 | SJ Earthquakes | 3.3 | 3–1 | 1.5 | FC Dallas | Earthquakes Stadium | Tim Ford | Spielbericht | ||
| Sa. | 24.04.2021 | 13:00 | NYCFC | 2.5 | 5–0 | 1.4 | FC Cincinnati | Yankee Stadium | Dave Gantar | Spielbericht | ||
| Sa. | 24.04.2021 | 13:00 | Nashville SC | 2.7 | 2–2 | 0.8 | CF Montréal | Nissan Stadium | Fotis Bazakos | Spielbericht | ||
| Sa. | 24.04.2021 | 15:00 | Toronto FC | 1.7 | 2–2 | 1.6 | Vancouver W'caps | Exploria Stadium | Jair Marrufo | Spielbericht | ||
| Sa. | 24.04.2021 | 15:00 | LAFC | 0.6 | 1–1 | 0.8 | Seattle Sounders | Banc of California Stadium | Armando Villarreal | Spielbericht | ||
| So. | 25.04.2021 | 14:30 | LA Galaxy | 2.0 | 3–2 | 1.2 | NY Red Bulls | Dignity Health Sports Park | Victor Rivas | Spielbericht | ||
| Sa. | 24.04.2021 | 19:00 | Colorado Rapids | 1.3 | 1–3 | 2.1 | Austin | Dick's Sporting Goods Park | Marcos de Oliveira | Spielbericht | ||
| Sa. | 24.04.2021 | 19:00 | Minnesota Utd | 1.7 | 1–2 | 1.4 | Real Salt Lake | 4.100 | Allianz Field | Drew Fischer | Spielbericht | |
| Sa. | 24.04.2021 | 19:30 | Portland Timbers | 2.6 | 2–1 | 1.2 | Houston Dynamo | Providence Park | Ismail Elfath | Spielbericht | ||
| Sa. | 24.04.2021 | 20:00 | NE Revolution | 0.2 | 1–0 | 0.3 | D.C. United | Gillette Stadium | Guido Gonzalez Jr. | Spielbericht | ||
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Sa. | 24.04.2021 | 20:00 | Atlanta Utd | 1.7 | 3–1 | 1.0 | Chicago Fire | 20.335 | Mercedes-Benz Stadium | Allen Chapman | Spielbericht | |
| Sa. | 24.04.2021 | 20:00 | Philadelphia Union | 0.9 | 1–2 | 1.0 | Inter Miami | 5.000 | Subaru Park | Alex Chilowicz | Spielbericht | |
| Sa. | 01.05.2021 | 12:00 | Real Salt Lake | 1.2 | 3–1 | 0.3 | Sporting KC | Rio Tinto Stadium | Dave Gantar | Spielbericht | ||
| Sa. | 01.05.2021 | 13:00 | NY Red Bulls | 1.6 | 2–0 | 0.3 | Chicago Fire | Red Bull Arena | Ted Unkel | Spielbericht | ||
| Sa. | 01.05.2021 | 14:30 | Houston Dynamo | 1.4 | 1–1 | 1.3 | LAFC | 7.850 | BBVA Stadium | Robert Sibiga | Spielbericht | |
| Sa. | 01.05.2021 | 15:00 | CF Montréal | 1.6 | 0–0 | 0.2 | Columbus Crew | DRV PNK Stadium | Tim Ford | Spielbericht | ||
| Sa. | 01.05.2021 | 19:00 | NE Revolution | 2.4 | 2–1 | 1.5 | Atlanta Utd | Gillette Stadium | Chris Penso | Spielbericht | ||
| Sa. | 01.05.2021 | 19:30 | Orlando City | 2.8 | 3–0 | 1.0 | FC Cincinnati | Exploria Stadium | Drew Fischer | Spielbericht | ||
| Sa. | 01.05.2021 | 19:30 | Philadelphia Union | 0.3 | 0–2 | 3.0 | NYCFC | Subaru Park | Ismail Elfath | Spielbericht | ||
| So. | 02.05.2021 | 12:00 | Nashville SC | 0.9 | 0–0 | 0.4 | Inter Miami | 13.855 | Nissan Stadium | Rosendo Mendoza | Spielbericht | |
| Sa. | 01.05.2021 | 19:00 | FC Dallas | 1.8 | 4–1 | 0.8 | Portland Timbers | 8.621 | Toyota Stadium | Alan Kelly | Spielbericht | |
| Sa. | 01.05.2021 | 19:00 | Minnesota Utd | 0.9 | 0–1 | 1.8 | Austin | 4.100 | Allianz Field | Ramy Touchan | Spielbericht | |
| Sa. | 01.05.2021 | 20:00 | SJ Earthquakes | 2.0 | 4–1 | 2.0 | D.C. United | Earthquakes Stadium | Kevin Stott | Spielbericht | ||
| So. | 02.05.2021 | 18:00 | Seattle Sounders | 2.1 | 3–0 | 0.9 | LA Galaxy | 7.148 | Lumen Field | Jair Marrufo | Spielbericht | |
| So. | 02.05.2021 | 20:00 | Vancouver W'caps | 0.7 | 0–1 | 2.0 | Colorado Rapids | Rio Tinto Stadium | Baldomero Toledo | Spielbericht | ||
| Sa. | 08.05.2021 | 12:00 | Vancouver W'caps | 1.5 | 2–0 | 1.5 | CF Montréal | Rio Tinto Stadium | Rosendo Mendoza | Spielbericht | ||
| Sa. | 08.05.2021 | 12:00 | Chicago Fire | 1.0 | 0–2 | 1.4 | Philadelphia Union | 6.457 | Soldier Field | Marcos de Oliveira | Spielbericht | |
| Sa. | 08.05.2021 | 12:30 | Nashville SC | 1.4 | 2–0 | 0.9 | NE Revolution | 12.510 | Nissan Stadium | Victor Rivas | Spielbericht | |
| Sa. | 08.05.2021 | 13:00 | NY Red Bulls | 1.7 | 2–0 | 0.4 | Toronto FC | Red Bull Arena | Guido Gonzalez Jr. | Spielbericht | ||
| Sa. | 08.05.2021 | 13:30 | Columbus Crew | 0.4 | 3–1 | 1.0 | D.C. United | 5.180 | MAPFRE Stadium | Silviu Petrescu | Spielbericht | |
| Sa. | 08.05.2021 | 14:30 | FC Dallas | 1.6 | 1–1 | 1.7 | Houston Dynamo | 8.749 | Toyota Stadium | Alex Chilowicz | Spielbericht | |
| Sa. | 08.05.2021 | 18:00 | Orlando City | 0.7 | 1–1 | 1.9 | NYCFC | 11.503 | Exploria Stadium | Robert Sibiga | Spielbericht | |
| Fr. | 07.05.2021 | 19:30 | Real Salt Lake | 1.1 | 1–2 | 2.0 | SJ Earthquakes | 10.448 | Rio Tinto Stadium | Fotis Bazakos | Spielbericht | |
| So. | 09.05.2021 | 12:00 | Portland Timbers | 1.7 | 1–2 | 2.4 | Seattle Sounders | Providence Park | Chris Penso | Spielbericht | ||
| So. | 09.05.2021 | 13:00 | Inter Miami | 2.2 | 1–1 | 1.3 | Atlanta Utd | 8.074 | DRV PNK Stadium | Joe Dickerson | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Sa. | 08.05.2021 | 17:00 | LA Galaxy | 1.0 | 2–1 | 1.2 | LAFC | 7.193 | Dignity Health Sports Park | Allen Chapman | Spielbericht | |
| So. | 09.05.2021 | 18:30 | Sporting KC | 3.6 | 2–1 | 0.9 | Austin | Children's Mercy Park | Ted Unkel | Spielbericht | ||
| Sa. | 08.05.2021 | 20:00 | Colorado Rapids | 1.2 | 3–2 | 1.3 | Minnesota Utd | Dick's Sporting Goods Park | Tim Ford | Spielbericht | ||
| Mi. | 12.05.2021 | 19:00 | Toronto FC | 2.2 | 2–0 | 0.7 | Columbus Crew | Exploria Stadium | Fotis Bazakos | Spielbericht | ||
| Mi. | 12.05.2021 | 19:30 | Philadelphia Union | 2.3 | 1–1 | 1.5 | NE Revolution | 5.000 | Subaru Park | Tori Penso | Spielbericht | |
| Mi. | 12.05.2021 | 19:30 | Inter Miami | 0.5 | 0–2 | 1.6 | CF Montréal | 8.220 | DRV PNK Stadium | Guido Gonzalez Jr. | Spielbericht | |
| Mi. | 12.05.2021 | 19:30 | Houston Dynamo | 1.5 | 1–0 | 2.1 | Sporting KC | 7.054 | BBVA Stadium | Chris Penso | Spielbericht | |
| Mi. | 12.05.2021 | 19:30 | SJ Earthquakes | 1.8 | 0–1 | 1.3 | Seattle Sounders | 5.000 | Earthquakes Stadium | Baldomero Toledo | Spielbericht | |
| Mi. | 12.05.2021 | 20:00 | Minnesota Utd | 1.6 | 1–0 | 0.8 | Vancouver W'caps | 4.100 | Allianz Field | Jon Freemon | Spielbericht | |
| Do. | 13.05.2021 | 20:00 | D.C. United | 1.4 | 1–0 | 1.8 | Chicago Fire | 3.935 | Audi Field | Ramy Touchan | Spielbericht | |
| Sa. | 15.05.2021 | 12:30 | LA Galaxy | 2.5 | 2–0 | 1.2 | Austin | 7.193 | Dignity Health Sports Park | Kevin Stott | Spielbericht | |
| Sa. | 15.05.2021 | 13:00 | NYCFC | 1.6 | 1–1 | 0.6 | Toronto FC | Yankee Stadium | Dave Gantar | Spielbericht | ||
| Sa. | 15.05.2021 | 19:00 | Atlanta Utd | 0.8 | 1–0 | 0.8 | CF Montréal | 40.116 | Mercedes-Benz Stadium | Silviu Petrescu | Spielbericht | |
| Sa. | 15.05.2021 | 19:30 | Philadelphia Union | 1.0 | 1–0 | 1.1 | NY Red Bulls | 5.000 | Subaru Park | Allen Chapman | Spielbericht | |
| So. | 16.05.2021 | 13:00 | Sporting KC | 3.2 | 3–0 | 1.1 | Vancouver W'caps | Children's Mercy Park | Alan Kelly | Spielbericht | ||
| So. | 16.05.2021 | 16:00 | FC Cincinnati | 1.2 | 2–3 | 1.9 | Inter Miami | 6.000 | TQL Stadium | Ramy Touchan | Spielbericht | |
| So. | 16.05.2021 | 18:00 | NE Revolution | 1.4 | 1–0 | 0.3 | Columbus Crew | Gillette Stadium | Robert Sibiga | Spielbericht | ||
| Sa. | 15.05.2021 | 19:00 | Colorado Rapids | 2.2 | 3–1 | 0.4 | Houston Dynamo | Dick's Sporting Goods Park | Victor Rivas | Spielbericht | ||
| Sa. | 15.05.2021 | 19:00 | SJ Earthquakes | 2.7 | 0–2 | 2.1 | Portland Timbers | Earthquakes Stadium | Tim Ford | Spielbericht | ||
| Sa. | 15.05.2021 | 19:00 | Minnesota Utd | 2.1 | 1–0 | 1.0 | FC Dallas | 4.100 | Allianz Field | Ted Unkel | Spielbericht | |
| Sa. | 15.05.2021 | 19:30 | Real Salt Lake | 0.8 | 0–0 | 1.0 | Nashville SC | 10.555 | Rio Tinto Stadium | Marcos de Oliveira | Spielbericht | |
| So. | 16.05.2021 | 18:30 | Seattle Sounders | 1.3 | 2–0 | 0.6 | LAFC | 7.173 | Lumen Field | Joe Dickerson | Spielbericht | |
| So. | 16.05.2021 | 20:00 | D.C. United | 0.9 | 0–1 | 0.6 | Orlando City | 5.280 | Audi Field | Alex Chilowicz | Spielbericht | |
| Sa. | 22.05.2021 | 12:30 | Portland Timbers | 3.3 | 3–0 | 1.2 | LA Galaxy | Providence Park | Alan Kelly | Spielbericht | ||
| Sa. | 22.05.2021 | 13:00 | CF Montréal | 2.6 | 1–2 | 1.5 | FC Cincinnati | DRV PNK Stadium | Fotis Bazakos | Spielbericht | ||
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Sa. | 22.05.2021 | 17:00 | Chicago Fire | 1.9 | 1–0 | 0.3 | Inter Miami | 10.844 | Soldier Field | Silviu Petrescu | Spielbericht | |
| Sa. | 22.05.2021 | 19:00 | Orlando City | 1.9 | 1–0 | 1.5 | Toronto FC | 11.525 | Exploria Stadium | Victor Rivas | Spielbericht | |
| Sa. | 22.05.2021 | 19:30 | NYCFC | 1.4 | 1–2 | 0.6 | Columbus Crew | 3.154 | Red Bull Arena | Drew Fischer | Spielbericht | |
| So. | 23.05.2021 | 13:30 | Seattle Sounders | 0.5 | 1–1 | 1.1 | Atlanta Utd | 11.011 | Lumen Field | Kevin Stott | Spielbericht | |
| Sa. | 22.05.2021 | 19:00 | FC Dallas | 2.9 | 2–2 | 1.1 | Real Salt Lake | 8.621 | Toyota Stadium | Joe Dickerson | Spielbericht | |
| Sa. | 22.05.2021 | 19:00 | SJ Earthquakes | 1.8 | 1–3 | 1.7 | Sporting KC | Earthquakes Stadium | Allen Chapman | Spielbericht | ||
| So. | 23.05.2021 | 19:15 | D.C. United | 1.2 | 0–1 | 1.2 | Philadelphia Union | 6.200 | Audi Field | Tim Ford | Spielbericht | |
| Sa. | 22.05.2021 | 19:30 | LAFC | 1.5 | 2–1 | 1.1 | Colorado Rapids | 10.483 | Banc of California Stadium | Ismail Elfath | Spielbericht | |
| Sa. | 22.05.2021 | 20:00 | NE Revolution | 3.7 | 3–1 | 1.2 | NY Red Bulls | Gillette Stadium | Jair Marrufo | Spielbericht | ||
| Sa. | 22.05.2021 | 20:00 | Houston Dynamo | 1.4 | 2–1 | 1.3 | Vancouver W'caps | 9.255 | BBVA Stadium | Dave Gantar | Spielbericht | |
| So. | 23.05.2021 | 20:00 | Nashville SC | 2.3 | 1–0 | 0.7 | Austin | 22.421 | Nissan Stadium | Chris Penso | Spielbericht | |
| Sa. | 29.05.2021 | 12:00 | Chicago Fire | 2.0 | 0–1 | 0.6 | CF Montréal | 6.680 | Soldier Field | Victor Rivas | Spielbericht | |
| Sa. | 29.05.2021 | 13:00 | NY Red Bulls | 1.7 | 2–1 | 1.2 | Orlando City | Red Bull Arena | Ismail Elfath | Spielbericht | ||
| Sa. | 29.05.2021 | 14:00 | LAFC | 2.3 | 1–2 | 1.0 | NYCFC | 10.703 | Banc of California Stadium | Kevin Stott | Spielbericht | |
| Sa. | 29.05.2021 | 15:00 | FC Cincinnati | 0.8 | 0–1 | 1.9 | NE Revolution | 11.000 | TQL Stadium | Dave Gantar | Spielbericht | |
| Sa. | 29.05.2021 | 15:00 | Columbus Crew | 1.1 | 2–1 | 1.0 | Toronto FC | 5.700 | MAPFRE Stadium | Allen Chapman | Spielbericht | |
| Sa. | 29.05.2021 | 15:30 | Atlanta Utd | 1.5 | 2–2 | 1.8 | Nashville SC | 40.748 | Mercedes-Benz Stadium | Alan Kelly | Spielbericht | |
| Sa. | 29.05.2021 | 16:00 | LA Galaxy | 1.6 | 1–0 | 1.9 | SJ Earthquakes | Dignity Health Sports Park | Joe Dickerson | Spielbericht | ||
| Sa. | 29.05.2021 | 19:00 | Colorado Rapids | 1.9 | 3–0 | 1.9 | FC Dallas | Dick's Sporting Goods Park | Guido Gonzalez Jr. | Spielbericht | ||
| So. | 30.05.2021 | 19:00 | Philadelphia Union | 2.8 | 3–0 | 1.2 | Portland Timbers | 6.635 | Subaru Park | Robert Sibiga | Spielbericht | |
| Sa. | 29.05.2021 | 19:30 | Real Salt Lake | 1.1 | 1–1 | 0.9 | Minnesota Utd | 10.853 | Rio Tinto Stadium | Jair Marrufo | Spielbericht | |
| Sa. | 29.05.2021 | 19:30 | Sporting KC | 2.3 | 3–2 | 2.1 | Houston Dynamo | 20.086 | Children's Mercy Park | Drew Fischer | Spielbericht | |
| Sa. | 29.05.2021 | 20:00 | Inter Miami | 0.7 | 0–3 | 2.2 | D.C. United | DRV PNK Stadium | Armando Villarreal | Spielbericht | ||
| So. | 30.05.2021 | 18:30 | Seattle Sounders | 1.0 | 0–0 | 0.9 | Austin | 12.895 | Lumen Field | Rosendo Mendoza | Spielbericht | |
| Sa. | 12.06.2021 | 14:00 | Sporting KC | 2.9 | 1–1 | 1.9 | Austin | 18.519 | Children's Mercy Park | Robert Sibiga | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Sa. | 19.06.2021 | 19:30 | FC Cincinnati | 2.2 | 0–2 | 0.8 | Colorado Rapids | 25.054 | TQL Stadium | Baldomero Toledo | Spielbericht | |
| Sa. | 19.06.2021 | 19:30 | NYCFC | 3.2 | 2–3 | 1.1 | NE Revolution | 4.929 | Red Bull Arena | Allen Chapman | Spielbericht | |
| Sa. | 19.06.2021 | 19:30 | Toronto FC | 2.4 | 2–3 | 1.3 | Orlando City | Exploria Stadium | Armando Villarreal | Spielbericht | ||
| Sa. | 19.06.2021 | 19:30 | Columbus Crew | 2.2 | 2–0 | 1.0 | Chicago Fire | 20.064 | MAPFRE Stadium | Alex Chilowicz | Spielbericht | |
| Fr. | 18.06.2021 | 20:00 | Real Salt Lake | 1.5 | 3–1 | 1.4 | Vancouver W'caps | 15.109 | Rio Tinto Stadium | Rubiel Vazquez | Spielbericht | |
| Fr. | 18.06.2021 | 20:00 | NY Red Bulls | 1.1 | 2–0 | 0.8 | Nashville SC | 10.173 | Red Bull Arena | Nima Saghafi | Spielbericht | |
| So. | 20.06.2021 | 14:00 | Atlanta Utd | 1.4 | 2–2 | 1.6 | Philadelphia Union | 42.523 | Mercedes-Benz Stadium | Ted Unkel | Spielbericht | |
| Sa. | 19.06.2021 | 18:00 | LA Galaxy | 1.4 | 1–2 | 1.6 | Seattle Sounders | 23.165 | Dignity Health Sports Park | Drew Fischer | Spielbericht | |
| Sa. | 19.06.2021 | 19:30 | FC Dallas | 1.0 | 1–1 | 2.1 | Minnesota Utd | 16.455 | Toyota Stadium | Marcos de Oliveira | Spielbericht | |
| Sa. | 19.06.2021 | 19:30 | Portland Timbers | 1.3 | 2–1 | 1.9 | Sporting KC | Providence Park | Alan Kelly | Spielbericht | ||
| Sa. | 19.06.2021 | 20:00 | Austin | 1.7 | 0–0 | 0.8 | SJ Earthquakes | Q2 Stadium | Ismail Elfath | Spielbericht | ||
| Sa. | 19.06.2021 | 20:00 | LAFC | 1.9 | 1–1 | 0.5 | Houston Dynamo | 22.043 | Banc of California Stadium | Joe Dickerson | Spielbericht | |
| Sa. | 19.06.2021 | 20:00 | D.C. United | 2.8 | 1–0 | 1.0 | Inter Miami | 16 | Audi Field | Fotis Bazakos | Spielbericht | |
| Di. | 22.06.2021 | 19:30 | Orlando City | 2.9 | 5–0 | 0.5 | SJ Earthquakes | 15.476 | Exploria Stadium | Chris Penso | Spielbericht | |
| Mi. | 23.06.2021 | 19:00 | NE Revolution | 1.6 | 3–2 | 1.5 | NY Red Bulls | Gillette Stadium | Robert Sibiga | Spielbericht | ||
| Mi. | 23.06.2021 | 19:30 | NYCFC | 2.2 | 1–0 | 0.3 | Atlanta Utd | 3.564 | Red Bull Arena | Ismail Elfath | Spielbericht | |
| Mi. | 23.06.2021 | 19:30 | Philadelphia Union | 0.5 | 1–0 | 0.5 | Columbus Crew | 16.234 | Subaru Park | Joe Dickerson | Spielbericht | |
| Mi. | 23.06.2021 | 19:00 | Minnesota Utd | 1.4 | 2–0 | 1.0 | Austin | 19.209 | Allianz Field | Silviu Petrescu | Spielbericht | |
| Mi. | 23.06.2021 | 19:00 | Seattle Sounders | 2.4 | 2–1 | 1.2 | Real Salt Lake | 24.652 | Lumen Field | Ted Unkel | Spielbericht | |
| Mi. | 23.06.2021 | 19:00 | Chicago Fire | 2.1 | 0–1 | 1.9 | FC Cincinnati | 5.926 | Soldier Field | Ismir Pekmic | Spielbericht | |
| Mi. | 23.06.2021 | 19:30 | Nashville SC | 2.4 | 3–2 | 1.7 | Toronto FC | 17.008 | Nissan Stadium | Ramy Touchan | Spielbericht | |
| Mi. | 23.06.2021 | 19:30 | Houston Dynamo | 1.9 | 2–2 | 1.6 | Portland Timbers | 10.791 | BBVA Stadium | Armando Villarreal | Spielbericht | |
| Mi. | 23.06.2021 | 19:30 | Sporting KC | 2.5 | 3–1 | 1.5 | Colorado Rapids | 18.690 | Children's Mercy Park | Dave Gantar | Spielbericht | |
| Mi. | 23.06.2021 | 19:30 | LAFC | 3.1 | 2–0 | 0.8 | FC Dallas | 22.510 | Banc of California Stadium | Rosendo Mendoza | Spielbericht | |
| Mi. | 23.06.2021 | 20:00 | CF Montréal | 0.2 | 0–0 | 2.8 | D.C. United | DRV PNK Stadium | Drew Fischer | Spielbericht | ||
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Mi. | 23.06.2021 | 20:30 | Vancouver W'caps | 1.2 | 1–2 | 1.0 | LA Galaxy | Rio Tinto Stadium | Tori Penso | Spielbericht | ||
| Sa. | 26.06.2021 | 16:30 | Sporting KC | 1.4 | 2–1 | 0.8 | LAFC | 20.213 | Children's Mercy Park | Chris Penso | Spielbericht | |
| Sa. | 26.06.2021 | 19:00 | Toronto FC | 0.5 | 0–2 | 1.4 | FC Cincinnati | Exploria Stadium | Rubiel Vazquez | Spielbericht | ||
| Fr. | 25.06.2021 | 20:00 | Inter Miami | 0.9 | 1–2 | 0.7 | Orlando City | 17.926 | DRV PNK Stadium | Allen Chapman | Spielbericht | |
| So. | 27.06.2021 | 15:30 | Atlanta Utd | 1.6 | 0–0 | 0.7 | NY Red Bulls | 42.575 | Mercedes-Benz Stadium | Alan Kelly | Spielbericht | |
| Sa. | 26.06.2021 | 18:00 | Real Salt Lake | 2.8 | 1–1 | 1.0 | Houston Dynamo | 13.588 | Rio Tinto Stadium | Nima Saghafi | Spielbericht | |
| So. | 27.06.2021 | 18:00 | NYCFC | 1.5 | 2–1 | 0.9 | D.C. United | 4.533 | Red Bull Arena | Robert Sibiga | Spielbericht | |
| Sa. | 26.06.2021 | 18:00 | Seattle Sounders | 2.5 | 2–2 | 1.6 | Vancouver W'caps | 25.603 | Lumen Field | Guido Gonzalez Jr. | Spielbericht | |
| Sa. | 26.06.2021 | 19:00 | Chicago Fire | 1.3 | 3–3 | 1.5 | Philadelphia Union | 7.308 | Soldier Field | Fotis Bazakos | Spielbericht | |
| Sa. | 26.06.2021 | 19:00 | SJ Earthquakes | 0.9 | 1–3 | 2.1 | LA Galaxy | 18.000 | Stanford Stadium | Armando Villarreal | Spielbericht | |
| Sa. | 26.06.2021 | 19:30 | Nashville SC | 2.1 | 1–1 | 0.6 | CF Montréal | 22.523 | Nissan Stadium | Jon Freemon | Spielbericht | |
| Sa. | 26.06.2021 | 20:30 | Portland Timbers | 1.8 | 0–1 | 2.6 | Minnesota Utd | Providence Park | Rosendo Mendoza | Spielbericht | ||
| So. | 27.06.2021 | 19:00 | Austin | 1.4 | 0–0 | 1.1 | Columbus Crew | 20.738 | Q2 Stadium | Ted Unkel | Spielbericht | |
| So. | 27.06.2021 | 20:00 | FC Dallas | 0.9 | 2–1 | 1.3 | NE Revolution | 14.889 | Toyota Stadium | Kevin Stott | Spielbericht | |
| Do. | 01.07.2021 | 20:30 | Austin | 1.7 | 4–1 | 0.6 | Portland Timbers | 20.738 | Q2 Stadium | Ted Unkel | Spielbericht | |
| Sa. | 03.07.2021 | 17:00 | Columbus Crew | 1.3 | 2–2 | 1.4 | NE Revolution | 20.407 | Lower.com Field | Alan Kelly | Spielbericht | |
| Sa. | 03.07.2021 | 17:30 | D.C. United | 3.1 | 7–1 | 1.2 | Toronto FC | 14.000 | Audi Field | Lukasz Szpala | Spielbericht | |
| Sa. | 03.07.2021 | 19:30 | Orlando City | 1.7 | 1–2 | 1.9 | NY Red Bulls | 19.009 | Exploria Stadium | Joe Dickerson | Spielbericht | |
| Sa. | 03.07.2021 | 19:30 | CF Montréal | 1.9 | 1–0 | 0.3 | Inter Miami | Red Bull Arena | Rosendo Mendoza | Spielbericht | ||
| Sa. | 03.07.2021 | 19:00 | Chicago Fire | 1.5 | 3–0 | 1.0 | Atlanta Utd | 14.898 | Soldier Field | Baldomero Toledo | Spielbericht | |
| Sa. | 03.07.2021 | 19:00 | Minnesota Utd | 2.8 | 2–2 | 0.8 | SJ Earthquakes | 19.687 | Allianz Field | Michael Radchuk | Spielbericht | |
| Sa. | 03.07.2021 | 19:00 | Nashville SC | 1.3 | 1–0 | 0.9 | Philadelphia Union | 21.822 | Nissan Stadium | Robert Sibiga | Spielbericht | |
| Sa. | 03.07.2021 | 19:30 | Houston Dynamo | 1.8 | 1–1 | 1.5 | FC Cincinnati | 20.021 | BBVA Stadium | Marcos de Oliveira | Spielbericht | |
| Sa. | 03.07.2021 | 20:00 | Real Salt Lake | 1.3 | 0–1 | 0.6 | LAFC | 18.253 | Rio Tinto Stadium | Silviu Petrescu | Spielbericht | |
| So. | 04.07.2021 | 19:00 | Colorado Rapids | 1.1 | 1–1 | 0.9 | Seattle Sounders | 17.104 | Dick's Sporting Goods Park | Kevin Stott | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| So. | 04.07.2021 | 19:30 | FC Dallas | 1.6 | 2–2 | 1.0 | Vancouver W'caps | 19.096 | Toyota Stadium | Ramy Touchan | Spielbericht | |
| So. | 04.07.2021 | 19:30 | LA Galaxy | 1.6 | 0–2 | 2.2 | Sporting KC | 23.556 | Dignity Health Sports Park | Alex Chilowicz | Spielbericht | |
| Mi. | 07.07.2021 | 19:00 | NE Revolution | 2.8 | 2–3 | 1.9 | Toronto FC | Gillette Stadium | Rosendo Mendoza | Spielbericht | ||
| Mi. | 07.07.2021 | 19:30 | CF Montréal | 2.3 | 2–1 | 0.6 | NYCFC | Exploria Stadium | Marcos de Oliveira | Spielbericht | ||
| Mi. | 07.07.2021 | 18:00 | Seattle Sounders | 2.2 | 2–0 | 0.8 | Houston Dynamo | 27.421 | Lumen Field | Robert Sibiga | Spielbericht | |
| Mi. | 07.07.2021 | 19:00 | Colorado Rapids | 1.6 | 2–0 | 0.7 | Minnesota Utd | Dick's Sporting Goods Park | Ted Unkel | Spielbericht | ||
| Mi. | 07.07.2021 | 19:00 | Chicago Fire | 1.6 | 3–1 | 2.6 | Orlando City | 8.002 | Soldier Field | Guido Gonzalez Jr. | Spielbericht | |
| Mi. | 07.07.2021 | 19:30 | LA Galaxy | 1.4 | 3–1 | 1.8 | FC Dallas | 16.453 | Dignity Health Sports Park | Alan Kelly | Spielbericht | |
| Mi. | 07.07.2021 | 20:00 | Austin | 0.7 | 0–2 | 2.0 | LAFC | 20.738 | Q2 Stadium | Ramy Touchan | Spielbericht | |
| Mi. | 07.07.2021 | 20:00 | Vancouver W'caps | 1.1 | 0–4 | 3.1 | Real Salt Lake | 12.009 | Rio Tinto Stadium | Alex Chilowicz | Spielbericht | |
| Fr. | 09.07.2021 | 19:30 | FC Cincinnati | 0.9 | 2–2 | 1.0 | Columbus Crew | 25.701 | TQL Stadium | Kevin Stott | Spielbericht | |
| Do. | 08.07.2021 | 19:30 | Nashville SC | 2.1 | 2–2 | 0.6 | Atlanta Utd | 22.913 | Nissan Stadium | Joe Dickerson | Spielbericht | |
| Do. | 08.07.2021 | 20:00 | NY Red Bulls | 2.1 | 1–1 | 0.9 | Philadelphia Union | 10.013 | Red Bull Arena | Victor Rivas | Spielbericht | |
| Sa. | 17.07.2021 | 17:00 | Atlanta Utd | 0.7 | 0–1 | 1.3 | NE Revolution | 42.517 | Mercedes-Benz Stadium | Victor Rivas | Spielbericht | |
| Sa. | 17.07.2021 | 19:30 | Philadelphia Union | 1.2 | 2–1 | 1.4 | D.C. United | 16.821 | Subaru Park | Alex Chilowicz | Spielbericht | |
| Sa. | 17.07.2021 | 19:30 | CF Montréal | 2.9 | 5–4 | 1.3 | FC Cincinnati | Stade Saputo | Silviu Petrescu | Spielbericht | ||
| Sa. | 17.07.2021 | 19:30 | Toronto FC | 0.7 | 1–1 | 1.3 | Orlando City | 7.000 | BMO Field | Marcos de Oliveira | Spielbericht | |
| Sa. | 17.07.2021 | 19:30 | Columbus Crew | 0.8 | 2–1 | 1.8 | NYCFC | 19.113 | Lower.com Field | Ramy Touchan | Spielbericht | |
| So. | 18.07.2021 | 13:00 | Minnesota Utd | 1.7 | 1–0 | 0.7 | Seattle Sounders | 19.679 | Allianz Field | Alan Kelly | Spielbericht | |
| Sa. | 17.07.2021 | 19:00 | Colorado Rapids | 0.8 | 1–1 | 0.4 | SJ Earthquakes | 14.664 | Dick's Sporting Goods Park | Rosendo Mendoza | Spielbericht | |
| Sa. | 17.07.2021 | 19:30 | Nashville SC | 3.4 | 5–1 | 1.9 | Chicago Fire | 23.113 | Nissan Stadium | Lukasz Szpala | Spielbericht | |
| Sa. | 17.07.2021 | 19:30 | Portland Timbers | 1.0 | 1–0 | 0.8 | FC Dallas | 23.255 | Providence Park | Joe Dickerson | Spielbericht | |
| Sa. | 17.07.2021 | 19:30 | LAFC | 4.8 | 2–1 | 0.9 | Real Salt Lake | 22.490 | Banc of California Stadium | Robert Sibiga | Spielbericht | |
| Sa. | 17.07.2021 | 20:00 | Vancouver W'caps | 1.5 | 2–1 | 0.8 | LA Galaxy | Rio Tinto Stadium | Ismir Pekmic | Spielbericht | ||
| Mi. | 21.07.2021 | 19:30 | Inter Miami | 1.2 | 0–5 | 3.3 | NE Revolution | 13.963 | DRV PNK Stadium | Robert Sibiga | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Mi. | 21.07.2021 | 19:30 | NYCFC | 1.9 | 1–0 | 0.5 | CF Montréal | 2.873 | Red Bull Arena | Ted Unkel | Spielbericht | |
| Mi. | 21.07.2021 | 19:30 | Toronto FC | 0.3 | 1–1 | 2.0 | NY Red Bulls | BMO Field | Silviu Petrescu | Spielbericht | ||
| Mi. | 21.07.2021 | 19:30 | Columbus Crew | 1.6 | 0–0 | 0.6 | Nashville SC | 18.395 | Lower.com Field | Rosendo Mendoza | Spielbericht | |
| Di. | 20.07.2021 | 20:00 | Vancouver W'caps | 0.7 | 0–0 | 0.3 | Houston Dynamo | Rio Tinto Stadium | Guido Gonzalez Jr. | Spielbericht | ||
| Mi. | 21.07.2021 | 19:00 | Chicago Fire | 0.6 | 2–2 | 2.2 | D.C. United | 8.306 | Soldier Field | Marcos de Oliveira | Spielbericht | |
| Mi. | 21.07.2021 | 19:00 | Colorado Rapids | 0.7 | 2–0 | 0.7 | FC Dallas | 8.321 | Dick's Sporting Goods Park | Jon Freemon | Spielbericht | |
| Do. | 22.07.2021 | 19:30 | Orlando City | 0.9 | 2–1 | 1.3 | Philadelphia Union | 15.432 | Exploria Stadium | Alan Kelly | Spielbericht | |
| Mi. | 21.07.2021 | 19:30 | Portland Timbers | 0.6 | 2–1 | 2.2 | LAFC | 23.500 | Providence Park | Victor Rivas | Spielbericht | |
| Mi. | 21.07.2021 | 19:30 | Sporting KC | 2.2 | 1–1 | 1.6 | SJ Earthquakes | 17.872 | Children's Mercy Park | Joe Dickerson | Spielbericht | |
| Mi. | 21.07.2021 | 20:00 | Real Salt Lake | 1.4 | 2–2 | 1.4 | LA Galaxy | 16.169 | Rio Tinto Stadium | Kevin Stott | Spielbericht | |
| Mi. | 21.07.2021 | 20:00 | FC Cincinnati | 1.0 | 1–1 | 1.9 | Atlanta Utd | 23.162 | TQL Stadium | Tori Penso | Spielbericht | |
| Do. | 22.07.2021 | 20:30 | Austin | 0.9 | 0–1 | 0.6 | Seattle Sounders | 20.738 | Q2 Stadium | Alex Chilowicz | Spielbericht | |
| Sa. | 24.07.2021 | 15:30 | Atlanta Utd | 1.8 | 0–1 | 1.7 | Columbus Crew | 67.507 | Mercedes-Benz Stadium | Robert Sibiga | Spielbericht | |
| So. | 25.07.2021 | 18:00 | NE Revolution | 1.4 | 2–1 | 1.8 | CF Montréal | 18.217 | Gillette Stadium | Alex Chilowicz | Spielbericht | |
| So. | 25.07.2021 | 18:00 | NYCFC | 3.9 | 5–0 | 0.6 | Orlando City | 13.503 | Yankee Stadium | Rosendo Mendoza | Spielbericht | |
| Sa. | 24.07.2021 | 19:00 | SJ Earthquakes | 1.1 | 1–1 | 0.7 | Houston Dynamo | 12.793 | Earthquakes Stadium | Ted Unkel | Spielbericht | |
| Sa. | 24.07.2021 | 19:00 | Chicago Fire | 3.9 | 1–2 | 0.8 | Toronto FC | 12.288 | Soldier Field | Victor Rivas | Spielbericht | |
| Sa. | 24.07.2021 | 19:00 | Minnesota Utd | 2.2 | 2–1 | 0.4 | Portland Timbers | 19.691 | Allianz Field | Marcos de Oliveira | Spielbericht | |
| So. | 25.07.2021 | 19:30 | Inter Miami | 1.1 | 1–1 | 1.6 | Philadelphia Union | 14.057 | DRV PNK Stadium | Joe Dickerson | Spielbericht | |
| Sa. | 24.07.2021 | 19:30 | LAFC | 1.0 | 2–2 | 1.2 | Vancouver W'caps | 22.049 | Banc of California Stadium | Kevin Stott | Spielbericht | |
| Sa. | 24.07.2021 | 19:30 | Nashville SC | 0.9 | 3–0 | 0.5 | FC Cincinnati | 23.832 | Nissan Stadium | Guido Gonzalez Jr. | Spielbericht | |
| Sa. | 24.07.2021 | 19:30 | FC Dallas | 1.7 | 4–0 | 1.4 | LA Galaxy | 14.812 | Toyota Stadium | Silviu Petrescu | Spielbericht | |
| Sa. | 24.07.2021 | 20:00 | Real Salt Lake | 1.0 | 3–0 | 0.5 | Colorado Rapids | 17.325 | Rio Tinto Stadium | Fotis Bazakos | Spielbericht | |
| So. | 25.07.2021 | 18:00 | Seattle Sounders | 0.9 | 1–3 | 1.1 | Sporting KC | 32.790 | Lumen Field | Ramy Touchan | Spielbericht | |
| So. | 25.07.2021 | 20:00 | D.C. United | 1.1 | 1–0 | 0.2 | NY Red Bulls | 15.912 | Audi Field | Alan Kelly | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Mi. | 28.07.2021 | 19:30 | LAFC | 2.2 | 2–2 | 1.1 | Minnesota Utd | 22.003 | Banc of California Stadium | Baldomero Toledo | Spielbericht | |
| Fr. | 30.07.2021 | 19:30 | NYCFC | 3.3 | 4–1 | 1.5 | Columbus Crew | Yankee Stadium | Alan Kelly | Spielbericht | ||
| Sa. | 31.07.2021 | 14:00 | Seattle Sounders | 1.0 | 0–1 | 0.6 | SJ Earthquakes | 32.704 | Lumen Field | Joe Dickerson | Spielbericht | |
| Sa. | 31.07.2021 | 18:00 | NY Red Bulls | 1.3 | 2–3 | 2.5 | NE Revolution | 13.444 | Red Bull Arena | Ramy Touchan | Spielbericht | |
| Fr. | 30.07.2021 | 19:00 | LA Galaxy | 3.0 | 4–1 | 1.0 | Portland Timbers | 15.644 | Dignity Health Sports Park | Robert Sibiga | Spielbericht | |
| Sa. | 31.07.2021 | 19:30 | FC Cincinnati | 1.7 | 0–0 | 0.5 | D.C. United | 25.060 | TQL Stadium | Rosendo Mendoza | Spielbericht | |
| Fr. | 30.07.2021 | 20:00 | Orlando City | 2.6 | 3–2 | 0.5 | Atlanta Utd | 18.910 | Exploria Stadium | Rubiel Vazquez | Spielbericht | |
| So. | 01.08.2021 | 18:00 | Philadelphia Union | 2.6 | 1–1 | 0.3 | Chicago Fire | 16.677 | Subaru Park | Michael Radchuk | Spielbericht | |
| Sa. | 31.07.2021 | 19:30 | Sporting KC | 1.7 | 1–2 | 1.1 | FC Dallas | 19.975 | Children's Mercy Park | Alex Chilowicz | Spielbericht | |
| Sa. | 31.07.2021 | 19:30 | Houston Dynamo | 1.4 | 0–0 | 1.4 | Real Salt Lake | 13.462 | BBVA Stadium | Guido Gonzalez Jr. | Spielbericht | |
| So. | 01.08.2021 | 19:30 | Toronto FC | 0.6 | 1–1 | 1.1 | Nashville SC | BMO Field | Fotis Bazakos | Spielbericht | ||
| Sa. | 31.07.2021 | 20:00 | Austin | 0.9 | 0–1 | 2.3 | Colorado Rapids | 20.738 | Q2 Stadium | Marcos de Oliveira | Spielbericht | |
| Sa. | 31.07.2021 | 20:00 | Vancouver W'caps | 1.7 | 2–2 | 1.2 | Minnesota Utd | Rio Tinto Stadium | Lukasz Szpala | Spielbericht | ||
| Sa. | 31.07.2021 | 20:00 | Inter Miami | 2.0 | 2–1 | 1.6 | CF Montréal | 14.303 | DRV PNK Stadium | Victor Rivas | Spielbericht | |
| Mi. | 04.08.2021 | 19:00 | NE Revolution | 0.6 | 0–0 | 0.5 | Nashville SC | 10.279 | Gillette Stadium | Silviu Petrescu | Spielbericht | |
| Mi. | 04.08.2021 | 19:30 | Philadelphia Union | 2.6 | 3–0 | 1.4 | Toronto FC | 14.303 | Subaru Park | Ted Unkel | Spielbericht | |
| Mi. | 04.08.2021 | 19:30 | Columbus Crew | 1.5 | 2–4 | 1.7 | D.C. United | 18.398 | Lower.com Field | Victor Rivas | Spielbericht | |
| Mi. | 04.08.2021 | 19:30 | CF Montréal | 1.6 | 2–2 | 1.8 | Atlanta Utd | 11.000 | Stade Saputo | Dave Gantar | Spielbericht | |
| Mi. | 04.08.2021 | 19:00 | Seattle Sounders | 2.0 | 1–1 | 1.2 | FC Dallas | 31.628 | Lumen Field | Fotis Bazakos | Spielbericht | |
| Mi. | 04.08.2021 | 19:00 | Chicago Fire | 0.3 | 0–0 | 1.4 | NYCFC | 8.371 | Soldier Field | Baldomero Toledo | Spielbericht | |
| Mi. | 04.08.2021 | 19:30 | Portland Timbers | 2.1 | 1–1 | 2.4 | SJ Earthquakes | 22.233 | Providence Park | Allen Chapman | Spielbericht | |
| Mi. | 04.08.2021 | 19:30 | LAFC | 2.3 | 1–4 | 2.0 | Sporting KC | 22.114 | Banc of California Stadium | Alan Kelly | Spielbericht | |
| Mi. | 04.08.2021 | 19:30 | LA Galaxy | 1.6 | 1–0 | 1.3 | Real Salt Lake | 15.544 | Dignity Health Sports Park | Nima Saghafi | Spielbericht | |
| Mi. | 04.08.2021 | 20:00 | Austin | 1.4 | 3–2 | 0.8 | Houston Dynamo | 20.738 | Q2 Stadium | Joe Dickerson | Spielbericht | |
| Mi. | 04.08.2021 | 20:00 | NY Red Bulls | 2.2 | 0–0 | 0.5 | FC Cincinnati | 9.203 | Red Bull Arena | Jon Freemon | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Mi. | 04.08.2021 | 20:00 | Orlando City | 1.0 | 1–1 | 0.2 | Inter Miami | 17.966 | Exploria Stadium | Armando Villarreal | Spielbericht | |
| Sa. | 07.08.2021 | 19:30 | FC Cincinnati | 1.2 | 1–1 | 1.2 | Orlando City | 24.113 | TQL Stadium | Fotis Bazakos | Spielbericht | |
| Sa. | 07.08.2021 | 19:30 | Columbus Crew | 1.7 | 2–3 | 2.7 | Atlanta Utd | 20.094 | Lower.com Field | Allen Chapman | Spielbericht | |
| So. | 08.08.2021 | 16:00 | SJ Earthquakes | 1.8 | 2–1 | 1.6 | LAFC | 18.000 | Earthquakes Stadium | Rubiel Vazquez | Spielbericht | |
| So. | 08.08.2021 | 17:00 | Chicago Fire | 1.1 | 2–1 | 1.3 | NY Red Bulls | 11.894 | Soldier Field | Guido Gonzalez Jr. | Spielbericht | |
| So. | 08.08.2021 | 18:00 | Inter Miami | 1.5 | 2–1 | 0.6 | Nashville SC | 14.062 | DRV PNK Stadium | Nima Saghafi | Spielbericht | |
| So. | 08.08.2021 | 18:00 | NE Revolution | 2.3 | 2–1 | 2.1 | Philadelphia Union | 17.054 | Gillette Stadium | Armando Villarreal | Spielbericht | |
| Sa. | 07.08.2021 | 19:00 | Colorado Rapids | 2.3 | 0–0 | 0.7 | Sporting KC | 11.753 | Dick's Sporting Goods Park | Ted Unkel | Spielbericht | |
| Sa. | 07.08.2021 | 19:00 | Minnesota Utd | 1.2 | 2–0 | 0.6 | Houston Dynamo | 19.625 | Allianz Field | Silviu Petrescu | Spielbericht | |
| Sa. | 07.08.2021 | 19:30 | FC Dallas | 1.1 | 2–0 | 1.2 | Austin | 16.625 | Toyota Stadium | Alan Kelly | Spielbericht | |
| Sa. | 07.08.2021 | 19:30 | Portland Timbers | 1.8 | 3–2 | 2.6 | Real Salt Lake | 23.577 | Providence Park | Rosendo Mendoza | Spielbericht | |
| Sa. | 07.08.2021 | 20:00 | Toronto FC | 2.5 | 2–2 | 1.3 | NYCFC | 9.331 | BMO Field | Robert Sibiga | Spielbericht | |
| So. | 08.08.2021 | 17:00 | LA Galaxy | 1.6 | 1–1 | 1.0 | Vancouver W'caps | 16.234 | Dignity Health Sports Park | Baldomero Toledo | Spielbericht | |
| So. | 08.08.2021 | 20:00 | D.C. United | 1.6 | 2–1 | 1.0 | CF Montréal | 14.169 | Audi Field | Marcos de Oliveira | Spielbericht | |
| Sa. | 14.08.2021 | 17:00 | Minnesota Utd | 2.0 | 0–1 | 1.6 | LA Galaxy | 19.787 | Allianz Field | Joe Dickerson | Spielbericht | |
| Fr. | 13.08.2021 | 19:30 | SJ Earthquakes | 1.0 | 0–0 | 1.0 | Vancouver W'caps | 11.967 | Earthquakes Stadium | Tim Ford | Spielbericht | |
| So. | 15.08.2021 | 16:00 | Atlanta Utd | 1.1 | 1–0 | 1.2 | LAFC | 67.503 | Mercedes-Benz Stadium | Chris Penso | Spielbericht | |
| So. | 15.08.2021 | 17:00 | Chicago Fire | 1.5 | 1–0 | 0.8 | Columbus Crew | 13.005 | Soldier Field | Nima Saghafi | Spielbericht | |
| So. | 15.08.2021 | 18:00 | Nashville SC | 2.1 | 5–2 | 0.9 | D.C. United | 20.022 | Nissan Stadium | Drew Fischer | Spielbericht | |
| Sa. | 14.08.2021 | 19:30 | Houston Dynamo | 2.7 | 1–3 | 1.8 | Colorado Rapids | 13.908 | BBVA Stadium | Rosendo Mendoza | Spielbericht | |
| Sa. | 14.08.2021 | 19:30 | FC Dallas | 1.7 | 0–2 | 0.9 | Sporting KC | 14.133 | Toyota Stadium | Armando Villarreal | Spielbericht | |
| Sa. | 14.08.2021 | 20:00 | Toronto FC | 1.1 | 1–2 | 1.3 | NE Revolution | BMO Field | Rubiel Vazquez | Spielbericht | ||
| Sa. | 14.08.2021 | 20:00 | NYCFC | 2.2 | 2–0 | 0.3 | Inter Miami | Red Bull Arena | Alex Chilowicz | Spielbericht | ||
| Sa. | 14.08.2021 | 20:00 | CF Montréal | 2.9 | 2–1 | 1.7 | NY Red Bulls | Stade Saputo | Allen Chapman | Spielbericht | ||
| Sa. | 14.08.2021 | 20:00 | Real Salt Lake | 1.5 | 1–0 | 1.1 | Austin | 17.506 | Rio Tinto Stadium | Dave Gantar | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| So. | 15.08.2021 | 19:00 | Portland Timbers | 1.8 | 2–6 | 2.4 | Seattle Sounders | 25.218 | Providence Park | Jair Marrufo | Spielbericht | |
| Mi. | 18.08.2021 | 19:00 | NE Revolution | 1.9 | 3–2 | 2.2 | D.C. United | 11.419 | Gillette Stadium | Ted Unkel | Spielbericht | |
| Mi. | 18.08.2021 | 19:00 | Atlanta Utd | 1.8 | 1–0 | 1.3 | Toronto FC | 42.502 | Mercedes-Benz Stadium | Alan Kelly | Spielbericht | |
| Mi. | 18.08.2021 | 19:30 | Philadelphia Union | 0.7 | 1–0 | 1.3 | NYCFC | 15.263 | Subaru Park | Drew Fischer | Spielbericht | |
| Di. | 17.08.2021 | 19:30 | SJ Earthquakes | 0.2 | 1–1 | 1.5 | Minnesota Utd | 10.353 | Earthquakes Stadium | Victor Rivas | Spielbericht | |
| Mi. | 18.08.2021 | 19:30 | FC Cincinnati | 0.9 | 0–0 | 0.4 | CF Montréal | 21.115 | TQL Stadium | Ramy Touchan | Spielbericht | |
| Di. | 17.08.2021 | 19:30 | LA Galaxy | 1.4 | 1–2 | 2.1 | Colorado Rapids | 15.101 | Dignity Health Sports Park | Silviu Petrescu | Spielbericht | |
| Mi. | 18.08.2021 | 19:30 | Inter Miami | 1.9 | 3–2 | 1.3 | Chicago Fire | 13.196 | DRV PNK Stadium | Baldomero Toledo | Spielbericht | |
| Mi. | 18.08.2021 | 19:30 | Sporting KC | 2.1 | 1–1 | 1.3 | Portland Timbers | 17.081 | Children's Mercy Park | Ismail Elfath | Spielbericht | |
| Mi. | 18.08.2021 | 19:30 | Nashville SC | 1.1 | 1–1 | 0.8 | Orlando City | 13.154 | Nissan Stadium | Fotis Bazakos | Spielbericht | |
| Mi. | 18.08.2021 | 19:30 | FC Dallas | 1.4 | 0–1 | 0.7 | Seattle Sounders | 11.535 | Toyota Stadium | Robert Sibiga | Spielbericht | |
| Mi. | 18.08.2021 | 20:00 | Austin | 0.9 | 1–2 | 2.3 | Vancouver W'caps | 20.738 | Q2 Stadium | Rosendo Mendoza | Spielbericht | |
| Mi. | 18.08.2021 | 20:00 | NY Red Bulls | 1.0 | 1–0 | 1.4 | Columbus Crew | 10.002 | Red Bull Arena | Chris Penso | Spielbericht | |
| Mi. | 18.08.2021 | 20:00 | Real Salt Lake | 1.0 | 2–1 | 1.4 | Houston Dynamo | 13.570 | Rio Tinto Stadium | Jair Marrufo | Spielbericht | |
| Sa. | 21.08.2021 | 14:30 | Minnesota Utd | 3.0 | 0–0 | 0.9 | Sporting KC | Allianz Field | Marcos de Oliveira | Spielbericht | ||
| Sa. | 21.08.2021 | 17:30 | Columbus Crew | 0.9 | 1–2 | 1.6 | Seattle Sounders | 19.401 | Lower.com Field | Joe Dickerson | Spielbericht | |
| Fr. | 20.08.2021 | 19:30 | LA Galaxy | 1.3 | 1–2 | 1.7 | SJ Earthquakes | 17.568 | Dignity Health Sports Park | Armando Villarreal | Spielbericht | |
| Sa. | 21.08.2021 | 19:00 | Vancouver W'caps | 1.5 | 2–1 | 3.9 | LAFC | BC Place Stadium | Alex Chilowicz | Spielbericht | ||
| Sa. | 21.08.2021 | 19:00 | Colorado Rapids | 1.7 | 2–1 | 1.9 | Real Salt Lake | 13.134 | Dick's Sporting Goods Park | Drew Fischer | Spielbericht | |
| Sa. | 21.08.2021 | 19:30 | Houston Dynamo | 2.3 | 2–2 | 0.9 | FC Dallas | 13.548 | BBVA Stadium | Allen Chapman | Spielbericht | |
| Sa. | 21.08.2021 | 20:00 | Austin | 3.0 | 3–1 | 1.0 | Portland Timbers | 20.738 | Q2 Stadium | Guido Gonzalez Jr. | Spielbericht | |
| Sa. | 21.08.2021 | 20:00 | Inter Miami | 2.8 | 3–1 | 0.8 | Toronto FC | 14.897 | DRV PNK Stadium | Jair Marrufo | Spielbericht | |
| Sa. | 21.08.2021 | 20:00 | NE Revolution | 1.8 | 4–1 | 0.9 | FC Cincinnati | 18.268 | Gillette Stadium | Fotis Bazakos | Spielbericht | |
| Sa. | 21.08.2021 | 20:00 | Orlando City | 0.9 | 1–0 | 1.4 | Chicago Fire | 15.538 | Exploria Stadium | Tim Ford | Spielbericht | |
| Sa. | 21.08.2021 | 20:00 | Philadelphia Union | 1.2 | 1–1 | 1.3 | CF Montréal | 14.794 | Subaru Park | Chris Penso | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Sa. | 21.08.2021 | 20:00 | D.C. United | 2.3 | 1–2 | 1.4 | Atlanta Utd | 17.180 | Audi Field | Nima Saghafi | Spielbericht | |
| Fr. | 27.08.2021 | 18:30 | Columbus Crew | 2.6 | 3–2 | 1.6 | FC Cincinnati | 19.949 | Lower.com Field | Robert Sibiga | Spielbericht | |
| Fr. | 27.08.2021 | 19:30 | CF Montréal | 2.7 | 3–1 | 0.5 | Toronto FC | Stade Saputo | Drew Fischer | Spielbericht | ||
| Sa. | 28.08.2021 | 15:30 | Atlanta Utd | 0.6 | 0–2 | 1.9 | Nashville SC | 42.506 | Mercedes-Benz Stadium | Rosendo Mendoza | Spielbericht | |
| Sa. | 28.08.2021 | 16:00 | LAFC | 2.9 | 3–3 | 1.3 | LA Galaxy | 22.032 | Banc of California Stadium | Allen Chapman | Spielbericht | |
| Sa. | 28.08.2021 | 18:00 | NY Red Bulls | 1.4 | 0–1 | 1.0 | Chicago Fire | 12.018 | Red Bull Arena | Victor Rivas | Spielbericht | |
| Sa. | 28.08.2021 | 19:30 | NYCFC | 1.9 | 2–0 | 1.3 | NE Revolution | Yankee Stadium | Kevin Stott | Spielbericht | ||
| Fr. | 27.08.2021 | 20:30 | Orlando City | 2.1 | 0–0 | 0.8 | Inter Miami | 17.817 | Exploria Stadium | Ismail Elfath | Spielbericht | |
| Sa. | 28.08.2021 | 20:00 | Sporting KC | 2.1 | 1–1 | 2.2 | Colorado Rapids | 19.883 | Children's Mercy Park | Fotis Bazakos | Spielbericht | |
| Sa. | 28.08.2021 | 20:00 | D.C. United | 2.8 | 3–1 | 0.4 | Philadelphia Union | 16.593 | Audi Field | Rubiel Vazquez | Spielbericht | |
| Sa. | 28.08.2021 | 20:00 | Houston Dynamo | 0.9 | 1–2 | 1.7 | Minnesota Utd | 14.521 | BBVA Stadium | Ted Unkel | Spielbericht | |
| So. | 29.08.2021 | 19:00 | Austin | 1.6 | 3–5 | 3.6 | FC Dallas | 20.738 | Q2 Stadium | Jair Marrufo | Spielbericht | |
| So. | 29.08.2021 | 19:00 | Vancouver W'caps | 2.0 | 4–1 | 1.0 | Real Salt Lake | 7.503 | BC Place Stadium | Ramy Touchan | Spielbericht | |
| So. | 29.08.2021 | 19:30 | Seattle Sounders | 1.5 | 0–2 | 1.4 | Portland Timbers | 45.737 | Lumen Field | Alan Kelly | Spielbericht | |
| Fr. | 03.09.2021 | 18:30 | Nashville SC | 1.0 | 3–1 | 1.7 | NYCFC | 20.126 | Nissan Stadium | Tim Ford | Spielbericht | |
| Fr. | 03.09.2021 | 19:30 | Philadelphia Union | 1.2 | 0–1 | 1.4 | NE Revolution | 15.152 | Subaru Park | Jair Marrufo | Spielbericht | |
| Sa. | 04.09.2021 | 16:00 | Vancouver W'caps | 2.0 | 2–1 | 1.4 | Austin | 9.223 | BC Place Stadium | Pierre-Luc Lauziere | Spielbericht | |
| Fr. | 03.09.2021 | 19:00 | Houston Dynamo | 1.2 | 0–2 | 2.1 | Portland Timbers | 9.872 | BBVA Stadium | Rubiel Vazquez | Spielbericht | |
| Fr. | 03.09.2021 | 19:00 | LAFC | 3.5 | 4–0 | 0.4 | Sporting KC | 22.018 | Banc of California Stadium | Drew Fischer | Spielbericht | |
| Sa. | 04.09.2021 | 19:30 | Orlando City | 1.6 | 3–2 | 0.8 | Columbus Crew | 15.366 | Exploria Stadium | Armando Villarreal | Spielbericht | |
| Sa. | 04.09.2021 | 18:00 | Real Salt Lake | 2.5 | 3–2 | 1.3 | FC Dallas | 15.882 | Rio Tinto Stadium | Baldomero Toledo | Spielbericht | |
| Sa. | 04.09.2021 | 19:00 | SJ Earthquakes | 1.3 | 0–1 | 1.5 | Colorado Rapids | 14.142 | Earthquakes Stadium | Joe Dickerson | Spielbericht | |
| Sa. | 04.09.2021 | 20:00 | FC Cincinnati | 0.7 | 0–1 | 1.1 | Inter Miami | 22.234 | TQL Stadium | Lukasz Szpala | Spielbericht | |
| Fr. | 10.09.2021 | 19:00 | Atlanta Utd | 1.3 | 3–0 | 0.4 | Orlando City | 42.507 | Mercedes-Benz Stadium | Victor Rivas | Spielbericht | |
| Sa. | 11.09.2021 | 14:00 | Seattle Sounders | 1.2 | 1–0 | 1.2 | Minnesota Utd | 33.130 | Lumen Field | Alex Chilowicz | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Sa. | 11.09.2021 | 15:30 | Colorado Rapids | 1.2 | 1–1 | 1.2 | LA Galaxy | 11.736 | Dick's Sporting Goods Park | Rosendo Mendoza | Spielbericht | |
| Sa. | 11.09.2021 | 19:00 | NE Revolution | 1.9 | 2–1 | 0.8 | NYCFC | 19.481 | Gillette Stadium | Chris Penso | Spielbericht | |
| Sa. | 11.09.2021 | 19:00 | NY Red Bulls | 0.7 | 1–1 | 2.0 | D.C. United | 12.574 | Red Bull Arena | Robert Sibiga | Spielbericht | |
| Fr. | 10.09.2021 | 19:00 | Vancouver W'caps | 1.2 | 0–1 | 0.9 | Portland Timbers | BC Place Stadium | Marcos de Oliveira | Spielbericht | ||
| Sa. | 11.09.2021 | 19:30 | Houston Dynamo | 1.6 | 3–0 | 1.1 | Austin | 14.070 | BBVA Stadium | Ismail Elfath | Spielbericht | |
| Sa. | 11.09.2021 | 19:30 | Sporting KC | 2.2 | 2–0 | 1.1 | Chicago Fire | 18.467 | Children's Mercy Park | Jon Freemon | Spielbericht | |
| Sa. | 11.09.2021 | 19:30 | FC Dallas | 1.4 | 1–1 | 1.6 | SJ Earthquakes | 15.237 | Toyota Stadium | Guido Gonzalez Jr. | Spielbericht | |
| Sa. | 11.09.2021 | 20:00 | Inter Miami | 0.7 | 1–0 | 0.6 | Columbus Crew | 15.014 | DRV PNK Stadium | Alan Kelly | Spielbericht | |
| Sa. | 11.09.2021 | 20:00 | CF Montréal | 0.9 | 0–1 | 1.1 | Nashville SC | Stade Saputo | Silviu Petrescu | Spielbericht | ||
| Sa. | 11.09.2021 | 20:00 | FC Cincinnati | 1.4 | 2–0 | 0.7 | Toronto FC | 22.636 | TQL Stadium | Dave Gantar | Spielbericht | |
| So. | 12.09.2021 | 19:30 | LAFC | 1.0 | 3–2 | 1.0 | Real Salt Lake | 22.130 | Banc of California Stadium | Ted Unkel | Spielbericht | |
| Di. | 14.09.2021 | 19:30 | NYCFC | 2.2 | 3–3 | 1.5 | FC Dallas | Yankee Stadium | Joe Dickerson | Spielbericht | ||
| Di. | 14.09.2021 | 19:30 | Columbus Crew | 1.5 | 2–1 | 1.0 | NY Red Bulls | 17.358 | Lower.com Field | Jair Marrufo | Spielbericht | |
| Di. | 14.09.2021 | 19:30 | Toronto FC | 1.0 | 0–1 | 1.7 | Inter Miami | 7.970 | BMO Field | Ramy Touchan | Spielbericht | |
| Mi. | 15.09.2021 | 19:00 | Atlanta Utd | 2.1 | 4–0 | 1.1 | FC Cincinnati | 42.501 | Mercedes-Benz Stadium | Drew Fischer | Spielbericht | |
| Mi. | 15.09.2021 | 19:30 | Orlando City | 0.7 | 2–4 | 1.7 | CF Montréal | 14.133 | Exploria Stadium | Rubiel Vazquez | Spielbericht | |
| Mi. | 15.09.2021 | 19:30 | D.C. United | 2.0 | 3–0 | 1.6 | Chicago Fire | 13.524 | Audi Field | Dave Gantar | Spielbericht | |
| Mi. | 15.09.2021 | 19:00 | Portland Timbers | 1.8 | 2–2 | 2.1 | Colorado Rapids | 16.808 | Providence Park | Armando Villarreal | Spielbericht | |
| Mi. | 15.09.2021 | 19:30 | Sporting KC | 1.9 | 4–0 | 0.9 | Minnesota Utd | 16.888 | Children's Mercy Park | Robert Sibiga | Spielbericht | |
| Mi. | 15.09.2021 | 19:30 | SJ Earthquakes | 1.2 | 3–4 | 2.6 | Real Salt Lake | 9.636 | Earthquakes Stadium | Nima Saghafi | Spielbericht | |
| Mi. | 15.09.2021 | 19:30 | LA Galaxy | 1.1 | 1–1 | 1.3 | Houston Dynamo | 15.341 | Dignity Health Sports Park | Kevin Stott | Spielbericht | |
| Mi. | 15.09.2021 | 20:00 | Austin | 1.3 | 1–2 | 2.5 | LAFC | 20.738 | Q2 Stadium | Tim Ford | Spielbericht | |
| Fr. | 17.09.2021 | 19:00 | Inter Miami | 0.1 | 0–4 | 3.3 | NY Red Bulls | 18.535 | DRV PNK Stadium | Guido Gonzalez Jr. | Spielbericht | |
| Sa. | 18.09.2021 | 15:30 | Atlanta Utd | 3.2 | 3–2 | 1.3 | D.C. United | 42.608 | Mercedes-Benz Stadium | Joe Dickerson | Spielbericht | |
| Sa. | 18.09.2021 | 19:00 | NE Revolution | 3.0 | 1–1 | 0.9 | Columbus Crew | 19.004 | Gillette Stadium | Allen Chapman | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Sa. | 18.09.2021 | 19:30 | Toronto FC | 1.2 | 2–1 | 1.8 | Nashville SC | 9.892 | BMO Field | Pierre-Luc Lauziere | Spielbericht | |
| Sa. | 18.09.2021 | 19:30 | FC Cincinnati | 0.9 | 1–2 | 1.4 | NYCFC | 21.978 | TQL Stadium | Ted Unkel | Spielbericht | |
| So. | 19.09.2021 | 13:00 | CF Montréal | 1.1 | 2–0 | 0.7 | Chicago Fire | Stade Saputo | Marcos de Oliveira | Spielbericht | ||
| So. | 19.09.2021 | 16:00 | Philadelphia Union | 2.1 | 3–1 | 0.7 | Orlando City | 15.032 | Subaru Park | Alan Kelly | Spielbericht | |
| So. | 19.09.2021 | 16:30 | Portland Timbers | 1.9 | 2–1 | 2.6 | LAFC | 21.311 | Providence Park | Chris Penso | Spielbericht | |
| Sa. | 18.09.2021 | 19:00 | Austin | 2.5 | 3–4 | 2.8 | SJ Earthquakes | 20.738 | Q2 Stadium | Baldomero Toledo | Spielbericht | |
| Sa. | 18.09.2021 | 19:00 | Minnesota Utd | 1.0 | 3–0 | 0.6 | LA Galaxy | 19.400 | Allianz Field | Jair Marrufo | Spielbericht | |
| Sa. | 18.09.2021 | 19:30 | Real Salt Lake | 1.9 | 1–0 | 0.5 | Seattle Sounders | 19.850 | Rio Tinto Stadium | Ismail Elfath | Spielbericht | |
| Sa. | 18.09.2021 | 20:30 | Houston Dynamo | 2.2 | 3–2 | 1.6 | FC Dallas | 12.353 | BBVA Stadium | Victor Rivas | Spielbericht | |
| So. | 19.09.2021 | 19:00 | Colorado Rapids | 2.1 | 1–1 | 0.9 | Vancouver W'caps | 8.454 | Dick's Sporting Goods Park | Rubiel Vazquez | Spielbericht | |
| Mi. | 22.09.2021 | 19:30 | Inter Miami | 0.9 | 1–5 | 3.3 | Nashville SC | 13.033 | DRV PNK Stadium | Jon Freemon | Spielbericht | |
| Mi. | 22.09.2021 | 19:00 | Chicago Fire | 2.8 | 2–3 | 1.9 | NE Revolution | 7.052 | Soldier Field | Lukasz Szpala | Spielbericht | |
| Mi. | 22.09.2021 | 20:00 | NY Red Bulls | 1.4 | 1–1 | 1.0 | NYCFC | 16.072 | Red Bull Arena | Ismail Elfath | Spielbericht | |
| Sa. | 25.09.2021 | 15:30 | Philadelphia Union | 1.5 | 1–0 | 0.3 | Atlanta Utd | Subaru Park | Robert Sibiga | Spielbericht | ||
| Sa. | 25.09.2021 | 19:00 | NE Revolution | 1.1 | 2–1 | 1.8 | Orlando City | 23.506 | Gillette Stadium | Rosendo Mendoza | Spielbericht | |
| Sa. | 25.09.2021 | 19:30 | NYCFC | 1.3 | 0–1 | 1.4 | NY Red Bulls | Yankee Stadium | Armando Villarreal | Spielbericht | ||
| Sa. | 25.09.2021 | 19:30 | D.C. United | 2.4 | 4–2 | 1.2 | FC Cincinnati | 16.069 | Audi Field | Chris Penso | Spielbericht | |
| Sa. | 25.09.2021 | 19:30 | Columbus Crew | 0.8 | 2–1 | 1.4 | CF Montréal | 19.423 | Lower.com Field | Nima Saghafi | Spielbericht | |
| So. | 26.09.2021 | 12:00 | Chicago Fire | 0.2 | 0–0 | 0.5 | Nashville SC | 15.915 | Soldier Field | Ismir Pekmic | Spielbericht | |
| Sa. | 25.09.2021 | 18:00 | Colorado Rapids | 0.7 | 0–0 | 0.5 | Toronto FC | 12.613 | Dick's Sporting Goods Park | Michael Radchuk | Spielbericht | |
| So. | 26.09.2021 | 18:00 | Sporting KC | 0.5 | 1–2 | 1.1 | Seattle Sounders | 19.248 | Children's Mercy Park | Joe Dickerson | Spielbericht | |
| Sa. | 25.09.2021 | 19:00 | Minnesota Utd | 1.3 | 2–0 | 1.6 | Houston Dynamo | 19.471 | Allianz Field | Allen Chapman | Spielbericht | |
| Sa. | 25.09.2021 | 19:00 | SJ Earthquakes | 1.7 | 2–0 | 1.3 | LAFC | 16.927 | Earthquakes Stadium | Jair Marrufo | Spielbericht | |
| Sa. | 25.09.2021 | 19:00 | Vancouver W'caps | 1.7 | 1–0 | 1.9 | FC Dallas | 16.927 | BC Place Stadium | Kevin Stott | Spielbericht | |
| Sa. | 25.09.2021 | 19:30 | Portland Timbers | 1.7 | 6–1 | 1.7 | Real Salt Lake | 21.579 | Providence Park | Fotis Bazakos | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| So. | 26.09.2021 | 20:30 | Austin | 1.0 | 2–0 | 1.2 | LA Galaxy | Q2 Stadium | Guido Gonzalez Jr. | Spielbericht | ||
| Mi. | 29.09.2021 | 19:00 | Toronto FC | 3.4 | 3–2 | 0.8 | FC Cincinnati | 5.110 | BMO Field | Silviu Petrescu | Spielbericht | |
| Mi. | 29.09.2021 | 19:00 | Atlanta Utd | 2.4 | 1–0 | 0.6 | Inter Miami | 42.519 | Mercedes-Benz Stadium | Ted Unkel | Spielbericht | |
| Mi. | 29.09.2021 | 19:30 | NY Red Bulls | 0.7 | 1–1 | 1.0 | Philadelphia Union | 9.193 | Red Bull Arena | Alex Chilowicz | Spielbericht | |
| Mi. | 29.09.2021 | 19:30 | CF Montréal | 1.8 | 1–4 | 1.9 | NE Revolution | Stade Saputo | Ismail Elfath | Spielbericht | ||
| Mi. | 29.09.2021 | 19:30 | D.C. United | 3.4 | 3–1 | 0.3 | Minnesota Utd | 12.262 | Audi Field | Ramy Touchan | Spielbericht | |
| Mi. | 29.09.2021 | 19:00 | Colorado Rapids | 1.2 | 3–0 | 0.5 | Austin | 8.582 | Dick's Sporting Goods Park | Michael Radchuk | Spielbericht | |
| Mi. | 29.09.2021 | 19:00 | Chicago Fire | 1.3 | 2–0 | 0.6 | NYCFC | 5.593 | Soldier Field | Baldomero Toledo | Spielbericht | |
| Mi. | 29.09.2021 | 19:00 | FC Dallas | 1.2 | 1–3 | 1.9 | Sporting KC | 12.387 | Toyota Stadium | Jair Marrufo | Spielbericht | |
| Mi. | 29.09.2021 | 19:30 | SJ Earthquakes | 0.8 | 1–3 | 2.2 | Seattle Sounders | 11.361 | Earthquakes Stadium | Allen Chapman | Spielbericht | |
| Mi. | 29.09.2021 | 19:30 | LAFC | 1.2 | 1–2 | 1.1 | Portland Timbers | 22.056 | Banc of California Stadium | Joe Dickerson | Spielbericht | |
| Mi. | 29.09.2021 | 19:30 | Nashville SC | 1.7 | 2–2 | 1.2 | Orlando City | 18.648 | Nissan Stadium | Drew Fischer | Spielbericht | |
| Mi. | 29.09.2021 | 19:30 | Real Salt Lake | 1.0 | 2–1 | 1.9 | LA Galaxy | 18.121 | Rio Tinto Stadium | Tori Penso | Spielbericht | |
| Mi. | 29.09.2021 | 20:00 | Houston Dynamo | 1.9 | 0–0 | 0.2 | Vancouver W'caps | 12.114 | BBVA Stadium | Alan Kelly | Spielbericht | |
| Sa. | 02.10.2021 | 14:30 | Austin | 3.1 | 2–1 | 1.3 | Real Salt Lake | Q2 Stadium | Rosendo Mendoza | Spielbericht | ||
| Sa. | 02.10.2021 | 19:00 | CF Montréal | 1.9 | 2–1 | 1.1 | Atlanta Utd | Stade Saputo | Fotis Bazakos | Spielbericht | ||
| Sa. | 02.10.2021 | 19:30 | FC Cincinnati | 0.5 | 0–1 | 1.3 | NY Red Bulls | 22.141 | TQL Stadium | Tim Ford | Spielbericht | |
| Sa. | 02.10.2021 | 19:30 | Orlando City | 1.4 | 2–1 | 0.6 | D.C. United | 16.848 | Exploria Stadium | Guido Gonzalez Jr. | Spielbericht | |
| So. | 03.10.2021 | 12:00 | NYCFC | 2.0 | 0–0 | 0.9 | Nashville SC | Red Bull Arena | Marcos de Oliveira | Spielbericht | ||
| So. | 03.10.2021 | 14:30 | Portland Timbers | 2.1 | 1–0 | 0.8 | Inter Miami | 22.006 | Providence Park | Robert Sibiga | Spielbericht | |
| So. | 03.10.2021 | 15:00 | Sporting KC | 3.5 | 4–2 | 1.9 | Houston Dynamo | 17.867 | Children's Mercy Park | Alex Chilowicz | Spielbericht | |
| So. | 03.10.2021 | 16:00 | Philadelphia Union | 1.2 | 3–0 | 1.4 | Columbus Crew | 15.578 | Subaru Park | Victor Rivas | Spielbericht | |
| So. | 03.10.2021 | 16:00 | Toronto FC | 2.7 | 3–1 | 0.8 | Chicago Fire | BMO Field | Nima Saghafi | Spielbericht | ||
| Sa. | 02.10.2021 | 19:00 | Vancouver W'caps | 2.5 | 3–0 | 0.6 | SJ Earthquakes | BC Place Stadium | Pierre-Luc Lauziere | Spielbericht | ||
| Sa. | 02.10.2021 | 19:00 | FC Dallas | 1.1 | 0–0 | 1.4 | Minnesota Utd | 17.231 | Toyota Stadium | Rubiel Vazquez | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| So. | 03.10.2021 | 17:00 | LA Galaxy | 1.6 | 1–1 | 1.3 | LAFC | 25.174 | Dignity Health Sports Park | Armando Villarreal | Spielbericht | |
| So. | 03.10.2021 | 19:00 | Seattle Sounders | 1.4 | 3–0 | 0.9 | Colorado Rapids | 31.425 | Lumen Field | Chris Penso | Spielbericht | |
| Sa. | 09.10.2021 | 18:00 | NY Red Bulls | 2.3 | 1–0 | 0.3 | Inter Miami | 17.516 | Red Bull Arena | Tori Penso | Spielbericht | |
| So. | 10.10.2021 | 15:00 | Minnesota Utd | 1.4 | 1–3 | 2.6 | Colorado Rapids | Allianz Field | Jon Freemon | Spielbericht | ||
| Sa. | 09.10.2021 | 18:00 | Seattle Sounders | 1.9 | 4–1 | 2.1 | Vancouver W'caps | 31.842 | Lumen Field | Ted Unkel | Spielbericht | |
| Sa. | 09.10.2021 | 20:00 | FC Cincinnati | 1.7 | 1–2 | 1.3 | Philadelphia Union | 21.674 | TQL Stadium | Lukasz Szpala | Spielbericht | |
| Sa. | 16.10.2021 | 12:30 | LAFC | 2.8 | 3–1 | 2.4 | SJ Earthquakes | 22.003 | Banc of California Stadium | Alan Kelly | Spielbericht | |
| Sa. | 16.10.2021 | 13:00 | CF Montréal | 0.8 | 2–2 | 0.2 | Philadelphia Union | Stade Saputo | Pierre-Luc Lauziere | Spielbericht | ||
| Sa. | 16.10.2021 | 18:00 | Columbus Crew | 2.5 | 4–0 | 0.7 | Inter Miami | 19.338 | Lower.com Field | Rubiel Vazquez | Spielbericht | |
| Sa. | 16.10.2021 | 19:00 | NE Revolution | 1.4 | 2–2 | 1.1 | Chicago Fire | 28.414 | Gillette Stadium | Joe Dickerson | Spielbericht | |
| Sa. | 16.10.2021 | 19:30 | FC Cincinnati | 0.6 | 0–1 | 1.1 | Orlando City | 22.488 | TQL Stadium | Marcos de Oliveira | Spielbericht | |
| Sa. | 16.10.2021 | 19:30 | Toronto FC | 1.4 | 0–2 | 1.8 | Atlanta Utd | 7.490 | BMO Field | Tim Ford | Spielbericht | |
| Sa. | 16.10.2021 | 19:30 | D.C. United | 1.1 | 0–0 | 0.3 | Nashville SC | 18.034 | Audi Field | Ismail Elfath | Spielbericht | |
| So. | 17.10.2021 | 13:00 | NY Red Bulls | 1.9 | 1–0 | 0.6 | NYCFC | 18.613 | Red Bull Arena | Jair Marrufo | Spielbericht | |
| Sa. | 16.10.2021 | 19:30 | Real Salt Lake | 1.2 | 3–1 | 0.7 | Colorado Rapids | Rio Tinto Stadium | Kevin Stott | Spielbericht | ||
| Sa. | 16.10.2021 | 19:30 | LA Galaxy | 3.1 | 2–1 | 0.4 | Portland Timbers | 15.322 | Dignity Health Sports Park | Victor Rivas | Spielbericht | |
| Sa. | 16.10.2021 | 19:30 | Houston Dynamo | 1.1 | 2–1 | 1.2 | Seattle Sounders | 14.265 | BBVA Stadium | Nima Saghafi | Spielbericht | |
| Sa. | 16.10.2021 | 20:00 | Austin | 1.5 | 0–1 | 1.8 | Minnesota Utd | 20.738 | Q2 Stadium | Michael Radchuk | Spielbericht | |
| So. | 17.10.2021 | 19:00 | Vancouver W'caps | 0.6 | 2–1 | 0.4 | Sporting KC | 10.990 | BC Place Stadium | Silviu Petrescu | Spielbericht | |
| Mi. | 20.10.2021 | 19:30 | FC Cincinnati | 2.6 | 3–4 | 2.3 | Chicago Fire | 21.369 | TQL Stadium | Jon Freemon | Spielbericht | |
| Mi. | 20.10.2021 | 19:30 | D.C. United | 2.1 | 2–3 | 1.9 | NE Revolution | 13.387 | Audi Field | Nima Saghafi | Spielbericht | |
| Mi. | 20.10.2021 | 19:30 | Atlanta Utd | 1.0 | 1–1 | 0.9 | NYCFC | 42.511 | Mercedes-Benz Stadium | Rubiel Vazquez | Spielbericht | |
| Mi. | 20.10.2021 | 19:30 | Orlando City | 1.4 | 1–1 | 0.8 | CF Montréal | 15.775 | Exploria Stadium | Robert Sibiga | Spielbericht | |
| Mi. | 20.10.2021 | 19:30 | Inter Miami | 1.5 | 3–0 | 0.7 | Toronto FC | DRV PNK Stadium | Armando Villarreal | Spielbericht | ||
| Mi. | 20.10.2021 | 19:00 | Portland Timbers | 1.2 | 2–3 | 1.8 | Vancouver W'caps | 16.722 | Providence Park | Guido Gonzalez Jr. | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Mi. | 20.10.2021 | 19:00 | FC Dallas | 2.0 | 2–3 | 1.8 | LAFC | 12.532 | Toyota Stadium | Chris Penso | Spielbericht | |
| Mi. | 20.10.2021 | 19:00 | Colorado Rapids | 1.2 | 1–1 | 1.4 | Seattle Sounders | 9.316 | Dick's Sporting Goods Park | Drew Fischer | Spielbericht | |
| Mi. | 20.10.2021 | 19:00 | Minnesota Utd | 1.5 | 3–2 | 2.2 | Philadelphia Union | Allianz Field | Allen Chapman | Spielbericht | ||
| Mi. | 20.10.2021 | 19:30 | Houston Dynamo | 2.1 | 0–3 | 1.8 | LA Galaxy | 13.798 | BBVA Stadium | Rosendo Mendoza | Spielbericht | |
| Mi. | 20.10.2021 | 19:30 | Nashville SC | 1.1 | 1–1 | 0.6 | Columbus Crew | 18.381 | Nissan Stadium | Alex Chilowicz | Spielbericht | |
| Mi. | 20.10.2021 | 19:30 | SJ Earthquakes | 2.6 | 4–0 | 1.0 | Austin | 12.035 | Earthquakes Stadium | Ismir Pekmic | Spielbericht | |
| Sa. | 23.10.2021 | 12:30 | Seattle Sounders | 1.7 | 1–2 | 1.2 | Sporting KC | 32.139 | Lumen Field | Ismail Elfath | Spielbericht | |
| Sa. | 23.10.2021 | 18:00 | Columbus Crew | 0.6 | 1–2 | 2.5 | NY Red Bulls | 17.891 | Lower.com Field | Alan Kelly | Spielbericht | |
| Sa. | 23.10.2021 | 19:30 | Philadelphia Union | 1.8 | 1–0 | 0.3 | Nashville SC | 18.575 | Subaru Park | Armando Villarreal | Spielbericht | |
| Sa. | 23.10.2021 | 19:30 | Toronto FC | 2.2 | 1–1 | 2.1 | CF Montréal | 8.095 | BMO Field | Allen Chapman | Spielbericht | |
| Sa. | 23.10.2021 | 19:30 | NYCFC | 3.1 | 6–0 | 0.7 | D.C. United | Yankee Stadium | Joe Dickerson | Spielbericht | ||
| So. | 24.10.2021 | 16:00 | Austin | 1.9 | 2–1 | 0.8 | Houston Dynamo | Q2 Stadium | Tim Ford | Spielbericht | ||
| Sa. | 23.10.2021 | 19:00 | SJ Earthquakes | 1.4 | 1–1 | 0.7 | Vancouver W'caps | 15.025 | Earthquakes Stadium | Marcos de Oliveira | Spielbericht | |
| Sa. | 23.10.2021 | 19:00 | Colorado Rapids | 1.4 | 2–0 | 0.4 | Portland Timbers | 12.200 | Dick's Sporting Goods Park | Ted Unkel | Spielbericht | |
| Sa. | 23.10.2021 | 19:00 | LA Galaxy | 2.0 | 2–2 | 1.5 | FC Dallas | 15.136 | Dignity Health Sports Park | Baldomero Toledo | Spielbericht | |
| Sa. | 23.10.2021 | 19:00 | Chicago Fire | 2.0 | 1–0 | 1.2 | Real Salt Lake | 31.308 | Soldier Field | Rosendo Mendoza | Spielbericht | |
| Sa. | 23.10.2021 | 19:00 | Minnesota Utd | 2.2 | 1–1 | 0.6 | LAFC | 19.406 | Allianz Field | Robert Sibiga | Spielbericht | |
| So. | 24.10.2021 | 19:30 | Orlando City | 2.0 | 2–2 | 1.3 | NE Revolution | 17.539 | Exploria Stadium | Chris Penso | Spielbericht | |
| Sa. | 23.10.2021 | 20:00 | Inter Miami | 2.1 | 5–1 | 1.8 | FC Cincinnati | 14.927 | DRV PNK Stadium | Drew Fischer | Spielbericht | |
| Mi. | 27.10.2021 | 19:00 | NE Revolution | 1.5 | 1–0 | 0.7 | Colorado Rapids | 10.199 | Gillette Stadium | Victor Rivas | Spielbericht | |
| Mi. | 27.10.2021 | 19:30 | Columbus Crew | 1.7 | 3–2 | 1.7 | Orlando City | 16.676 | Lower.com Field | Joe Dickerson | Spielbericht | |
| Mi. | 27.10.2021 | 19:30 | NYCFC | 2.1 | 1–0 | 0.5 | Chicago Fire | Red Bull Arena | Fotis Bazakos | Spielbericht | ||
| Di. | 26.10.2021 | 19:30 | LAFC | 1.1 | 3–0 | 1.7 | Seattle Sounders | 22.030 | Banc of California Stadium | Kevin Stott | Spielbericht | |
| Mi. | 27.10.2021 | 19:30 | Toronto FC | 1.3 | 2–2 | 2.0 | Philadelphia Union | 5.026 | BMO Field | Silviu Petrescu | Spielbericht | |
| Mi. | 27.10.2021 | 19:30 | Atlanta Utd | 1.5 | 2–1 | 2.1 | Inter Miami | 42.536 | Mercedes-Benz Stadium | Guido Gonzalez Jr. | Spielbericht | |
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| Mi. | 27.10.2021 | 19:30 | D.C. United | 0.9 | 1–0 | 2.2 | NY Red Bulls | 14.109 | Audi Field | Rubiel Vazquez | Spielbericht | |
| Mi. | 27.10.2021 | 19:30 | FC Cincinnati | 2.4 | 3–6 | 1.8 | Nashville SC | 20.581 | TQL Stadium | Ramy Touchan | Spielbericht | |
| Mi. | 27.10.2021 | 19:00 | Vancouver W'caps | 1.0 | 2–1 | 2.3 | Minnesota Utd | 10.833 | BC Place Stadium | Nima Saghafi | Spielbericht | |
| Mi. | 27.10.2021 | 19:00 | FC Dallas | 1.7 | 1–2 | 1.3 | Real Salt Lake | 12.486 | Toyota Stadium | Ismail Elfath | Spielbericht | |
| Mi. | 27.10.2021 | 19:00 | Portland Timbers | 3.2 | 2–0 | 1.2 | SJ Earthquakes | 16.086 | Providence Park | Alex Chilowicz | Spielbericht | |
| Mi. | 27.10.2021 | 19:30 | Sporting KC | 0.7 | 2–0 | 0.7 | LA Galaxy | 18.711 | Children's Mercy Park | Alan Kelly | Spielbericht | |
| Sa. | 30.10.2021 | 13:30 | Real Salt Lake | 2.3 | 3–4 | 2.7 | SJ Earthquakes | 15.553 | Rio Tinto Stadium | Jon Freemon | Spielbericht | |
| Sa. | 30.10.2021 | 13:30 | Inter Miami | 1.1 | 1–3 | 1.4 | NYCFC | 17.595 | DRV PNK Stadium | Rosendo Mendoza | Spielbericht | |
| Sa. | 30.10.2021 | 16:00 | NY Red Bulls | 1.4 | 1–0 | 0.9 | CF Montréal | 16.344 | Red Bull Arena | Chris Penso | Spielbericht | |
| Sa. | 30.10.2021 | 18:00 | Atlanta Utd | 2.4 | 1–1 | 0.9 | Toronto FC | 43.372 | Mercedes-Benz Stadium | Alex Chilowicz | Spielbericht | |
| Sa. | 30.10.2021 | 19:30 | D.C. United | 0.9 | 1–3 | 2.7 | Columbus Crew | 16.787 | Audi Field | Drew Fischer | Spielbericht | |
| So. | 31.10.2021 | 12:00 | Minnesota Utd | 1.8 | 2–1 | 0.6 | Sporting KC | Allianz Field | Victor Rivas | Spielbericht | ||
| So. | 31.10.2021 | 14:00 | Houston Dynamo | 0.6 | 0–1 | 0.4 | Colorado Rapids | 14.474 | BBVA Stadium | Guido Gonzalez Jr. | Spielbericht | |
| So. | 31.10.2021 | 16:00 | Orlando City | 1.0 | 1–1 | 0.8 | Nashville SC | 15.959 | Exploria Stadium | Allen Chapman | Spielbericht | |
| So. | 31.10.2021 | 19:30 | Philadelphia Union | 2.8 | 2–0 | 0.5 | FC Cincinnati | 13.488 | Subaru Park | Fotis Bazakos | Spielbericht | |
| Sa. | 30.10.2021 | 20:00 | FC Dallas | 1.6 | 2–1 | 0.5 | Austin | 16.080 | Toyota Stadium | Silviu Petrescu | Spielbericht | |
| Mo. | 01.11.2021 | 19:00 | Seattle Sounders | 1.4 | 1–1 | 1.1 | LA Galaxy | 32.781 | Lumen Field | Joe Dickerson | Spielbericht | |
| Di. | 02.11.2021 | 19:30 | LAFC | 3.1 | 1–1 | 0.8 | Vancouver W'caps | 22.221 | Banc of California Stadium | Alex Chilowicz | Spielbericht | |
| Mi. | 03.11.2021 | 19:30 | NY Red Bulls | 1.3 | 0–0 | 0.2 | Atlanta Utd | 15.934 | Red Bull Arena | Alan Kelly | Spielbericht | |
| Mi. | 03.11.2021 | 19:30 | CF Montréal | 1.3 | 2–0 | 0.7 | Houston Dynamo | Stade Saputo | Ted Unkel | Spielbericht | ||
| Mi. | 03.11.2021 | 20:00 | Austin | 2.0 | 3–1 | 0.7 | Sporting KC | 20.738 | Q2 Stadium | Nima Saghafi | Spielbericht | |
| Mi. | 03.11.2021 | 20:30 | Real Salt Lake | 2.2 | 1–3 | 1.8 | Portland Timbers | 18.405 | Rio Tinto Stadium | Chris Penso | Spielbericht | |
| So. | 07.11.2021 | 14:30 | Nashville SC | 1.0 | 1–1 | 1.6 | NY Red Bulls | 26.913 | Nissan Stadium | Drew Fischer | Spielbericht | |
| So. | 07.11.2021 | 15:00 | Portland Timbers | 4.2 | 3–0 | 0.4 | Austin | 23.127 | Providence Park | Rosendo Mendoza | Spielbericht | |
| So. | 07.11.2021 | 15:00 | SJ Earthquakes | 2.6 | 1–1 | 1.6 | FC Dallas | Earthquakes Stadium | Victor Rivas | Spielbericht | ||
| Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
| So. | 07.11.2021 | 15:00 | LA Galaxy | 2.1 | 3–3 | 2.6 | Minnesota Utd | 23.803 | Dignity Health Sports Park | Kevin Stott | Spielbericht | |
| So. | 07.11.2021 | 15:00 | Vancouver W'caps | 1.0 | 1–1 | 1.6 | Seattle Sounders | 25.117 | BC Place Stadium | Fotis Bazakos | Spielbericht | |
| So. | 07.11.2021 | 15:30 | NYCFC | 0.6 | 1–1 | 1.6 | Philadelphia Union | Yankee Stadium | Guido Gonzalez Jr. | Spielbericht | ||
| So. | 07.11.2021 | 15:30 | NE Revolution | 2.0 | 0–1 | 0.5 | Inter Miami | 31.635 | Gillette Stadium | Alan Kelly | Spielbericht | |
| So. | 07.11.2021 | 15:30 | CF Montréal | 1.4 | 0–2 | 0.7 | Orlando City | Stade Saputo | Armando Villarreal | Spielbericht | ||
| So. | 07.11.2021 | 15:30 | FC Cincinnati | 0.6 | 1–2 | 2.3 | Atlanta Utd | 23.663 | TQL Stadium | Nima Saghafi | Spielbericht | |
| So. | 07.11.2021 | 15:30 | Columbus Crew | 4.0 | 2–0 | 0.7 | Chicago Fire | 19.351 | Lower.com Field | Tim Ford | Spielbericht | |
| So. | 07.11.2021 | 15:30 | Toronto FC | 1.4 | 1–3 | 2.6 | D.C. United | 11.166 | BMO Field | Marcos de Oliveira | Spielbericht | |
| So. | 07.11.2021 | 16:00 | Colorado Rapids | 3.1 | 5–2 | 1.8 | LAFC | 16.292 | Dick's Sporting Goods Park | Allen Chapman | Spielbericht | |
| So. | 07.11.2021 | 17:00 | Sporting KC | 1.3 | 0–1 | 1.5 | Real Salt Lake | 19.022 | Children's Mercy Park | Ted Unkel | Spielbericht |
| Runde | Tag | Datum | Uhrzeit | Heim | xG | Ergebnis | xG | Auswärts | Zuschauerzahl | Spielort | Schiedsrichter | Spielbericht | Hinweise |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Erste Runde | Sa. | 20.11.2021 | 14:30 | Philadelphia Union | 2.0 | 1–0 | 0.9 | NY Red Bulls | 18.623 | Subaru Park | Fotis Bazakos | Spielbericht | Vorgeschriebene Nachspielzeit |
| Erste Runde | Sa. | 20.11.2021 | 16:00 | Sporting KC | 1.4 | 3–1 | 1.1 | Vancouver W'caps | 19.817 | Children's Mercy Park | Alan Kelly | Spielbericht | |
| Erste Runde | So. | 21.11.2021 | 14:30 | Portland Timbers | 2.3 | 3–1 | 1.7 | Minnesota Utd | 22.533 | Providence Park | Armando Villarreal | Spielbericht | |
| Erste Runde | So. | 21.11.2021 | 15:00 | NYCFC | 1.1 | 2–0 | 0.4 | Atlanta Utd | 25.267 | Yankee Stadium | Chris Penso | Spielbericht | |
| Erste Runde | Di. | 23.11.2021 | 19:00 | Nashville SC | 0.5 | 3–1 | 0.5 | Orlando City | 26.043 | Nissan Stadium | Ismail Elfath | Spielbericht | |
| Erste Runde | Di. | 23.11.2021 | 19:30 | Seattle Sounders | 1.1 | (5) 0–0 (6) | 0.0 | Real Salt Lake | 34.012 | Lumen Field | Joe Dickerson | Spielbericht | Real Salt Lake gewann durch Elfmeterschießen nach Verlängerung |
| Conference Halbfinale | Do. | 25.11.2021 | 14:30 | Colorado Rapids | 1.2 | 0–1 | 2.0 | Portland Timbers | 17.438 | Dick's Sporting Goods Park | Ted Unkel | Spielbericht | |
| Conference Halbfinale | So. | 28.11.2021 | 14:00 | Sporting KC | 1.0 | 1–2 | 1.1 | Real Salt Lake | 21.650 | Children's Mercy Park | Kevin Stott | Spielbericht | |
| Conference Halbfinale | So. | 28.11.2021 | 17:30 | Philadelphia Union | 2.0 | (2) 1–1 (0) | 0.9 | Nashville SC | 19.076 | Subaru Park | Allen Chapman | Spielbericht | Philadelphia Union gewann durch Elfmeterschießen nach Verlängerung |
| Conference Halbfinale | Di. | 30.11.2021 | 19:30 | NE Revolution | 1.1 | (3) 2–2 (5) | 0.9 | NYCFC | 25.509 | Gillette Stadium | Drew Fischer | Spielbericht | NYCFC gewann durch Elfmeterschießen nach Verlängerung |
| Conference Finale | Sa. | 04.12.2021 | 15:30 | Portland Timbers | 1.3 | 2–0 | 0.4 | Real Salt Lake | Providence Park | Alan Kelly | Spielbericht | ||
| Conference Finale | So. | 05.12.2021 | 15:00 | Philadelphia Union | 0.7 | 1–2 | 1.6 | NYCFC | 19.487 | Subaru Park | Ted Unkel | Spielbericht | |
| MLS Cup | Sa. | 11.12.2021 | 12:00 | Portland Timbers | 1.3 | (2) 1–1 (4) | 0.9 | NYCFC | 25.218 | Providence Park | Armando Villarreal | Spielbericht | NYCFC gewann durch Elfmeterschießen nach Verlängerung |
Über FBref.com
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